JPS5967971A - Nuclear magnetic resonance apparatus - Google Patents
Nuclear magnetic resonance apparatusInfo
- Publication number
- JPS5967971A JPS5967971A JP57178539A JP17853982A JPS5967971A JP S5967971 A JPS5967971 A JP S5967971A JP 57178539 A JP57178539 A JP 57178539A JP 17853982 A JP17853982 A JP 17853982A JP S5967971 A JPS5967971 A JP S5967971A
- Authority
- JP
- Japan
- Prior art keywords
- magnetic field
- magnetic resonance
- nuclear magnetic
- resonance apparatus
- static magnetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
(57)【要約】本公報は電子出願前の出願データであるた
め要約のデータは記録されません。(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.
Description
【発明の詳細な説明】
［唖明の属する技術分野］
この発明は核磁気共鳴を利用して、生体内の悪性腫瘍な
どを治療する装置に関する。DETAILED DESCRIPTION OF THE INVENTION [Technical field to which the present invention pertains] This invention relates to a device for treating malignant tumors in a living body using nuclear magnetic resonance.
［従来技術とその問題点］
この発明に関係の深い従来技術例としては、放射線治療
装置、レーザー治療装置、マイクロウェーブハイパサー
ミア装置などがある。これらの装置は、放射線（高エネ
ルギーＸ線、電子線など）、レーザー光、マイクロウェ
ーブなどのエネルギーと生体内部あるいは表面との相互
作用により悪性腫瘍などを治療することを目的としてい
る。そして、現在までに臨床的にそれを９の成果は収め
ている。しかしながら問題点としては、エネルギーを目
標とする悪性腫瘍のみに集中させることが困難であり、
正常細胞の損傷が生じたり、生体内部への適用がむずか
しいなどの欠点を有する。[Prior art and its problems] Examples of prior art closely related to the present invention include radiation therapy equipment, laser therapy equipment, and microwave hyperthermia equipment. These devices are intended to treat malignant tumors and the like through the interaction of energy such as radiation (high-energy X-rays, electron beams, etc.), laser light, microwaves, etc., with the interior or surface of a living body. To date, nine clinical results have been achieved. However, the problem is that it is difficult to concentrate energy only on the target malignant tumor.
It has drawbacks such as damage to normal cells and difficulty in applying it inside a living body.
［発明の目的］
この発明は上述した各種治療装置の欠点を改良したもの
で、エネルギーを生体内部の任意の個所に集中させるこ
とのできる核磁気共鳴治療装置を提供することを目的と
する。[Object of the Invention] This invention improves the drawbacks of the various treatment devices described above, and aims to provide a nuclear magnetic resonance treatment device that can concentrate energy at any desired location inside a living body.
［発明の概要］
核磁気共鳴現象によるエネルギー吸収は、静磁場強度に
よシ決定される周波数で変化する磁場によりなされる。SUMMARY OF THE INVENTION Energy absorption by nuclear magnetic resonance phenomena is accomplished by a magnetic field that varies at a frequency determined by the static magnetic field strength.
したがって生体内での静磁場を発生させる静磁場発生器
と、変化磁場を発生させる変化磁場発生器を組み合せる
ことにより、生体内の特定の領域（悪性腫瘍などの領域
）のみに核磁気共鳴を起こさせエネルギーを吸収させる
ことができる。本発明の装置はこのような原理により動
作するものであり、静磁場の空間的強度分布と変化磁場
の周波数は悪性腫瘍などの幾可学的形状により設定され
る。Therefore, by combining a static magnetic field generator that generates a static magnetic field in the living body and a variable magnetic field generator that generates a changing magnetic field, nuclear magnetic resonance can be applied only to a specific region within the living body (region such as a malignant tumor). It can wake up and absorb energy. The device of the present invention operates on this principle, and the spatial intensity distribution of the static magnetic field and the frequency of the changing magnetic field are set depending on the geometrical shape of a malignant tumor or the like.
［発明の効果］
本発明の装置によ）、生体内部の治療すべき特定領域の
みにエネルギーを集中させることができ、正常細胞への
損傷が生じない。又、生体深部への適用も容易である。[Effects of the Invention] With the device of the present invention, energy can be concentrated only in a specific region to be treated inside a living body, and normal cells are not damaged. Furthermore, it is easy to apply to deep parts of the body.
、［発明の実施例］
本発明の実施例を第１図に示す。図中、１は生体、２は
静磁場発生器、３は高周波磁場発生器、４．５は電磁石
の極、６は電磁コイルをそれぞれ示す。この装置の動作
原理を第２図を用いて説明する。図中７は正常部分、８
は悪性腫瘍部分である。説明を簡単にするために、最初
にＸ方向の領域について考えてみる。図に示されている
ように静磁場ＨはＸに対して減少関数になるように静磁
場発生器が調節されている。このとき悪性腫瘍の領域Ｘ
１ ＜ Ｘ≦Ｘ２に対してＨ１≦Ｈ≦Ｈ２が成立する
。, [Embodiments of the Invention] An embodiment of the present invention is shown in FIG. In the figure, 1 is a living body, 2 is a static magnetic field generator, 3 is a high frequency magnetic field generator, 4.5 is a pole of an electromagnet, and 6 is an electromagnetic coil. The operating principle of this device will be explained using FIG. In the figure, 7 is the normal part, 8
is the malignant tumor part. To simplify the explanation, first consider the region in the X direction. The static magnetic field generator is adjusted so that the static magnetic field H is a decreasing function of X as shown in the figure. At this time, the area of malignant tumor
H1≦H≦H2 holds true for 1<X≦X2.
しだがって核磁気共鳴現象の理論から、高周波磁場発生
器より周波数ｆが−Ｈ，＜ｆ ＜−５Ｈ２なる条件２π
を満足するような変化磁場を静磁場と垂直方向に印加す
ると、領域ｘ１≦Ｘ≦ｘ２に存在する水素核（プロトン
）に対してエネルギー吸収が生ずる。Therefore, from the theory of nuclear magnetic resonance phenomena, if a high-frequency magnetic field generator applies a changing magnetic field such that the frequency f satisfies the condition 2π of -H, < f < -5H2 in the direction perpendicular to the static magnetic field, the area x1 Energy absorption occurs for hydrogen nuclei (protons) present in ≦X≦x2.
（ここでγは磁気回転比： ｇｙｒｏｍａｇｎｅｔｉｃ
ｒａｔｉｏを表わしている。）このようなエネルギー
吸収により悪性腫瘍部分は生化学的な変化を受けると同
時に温度が上昇し、すでに臨床学的に経験されているよ
うに悪性腫瘍の進行が抑制される。(Here, γ is the gyromagnetic ratio: gyromagnetic
It represents the ratio. ) Due to such energy absorption, the malignant tumor region undergoes biochemical changes and at the same time its temperature rises, suppressing the progression of the malignant tumor as has already been clinically experienced.
上述の説明を三次元的に拡張すると次のようになる。ま
ず、静磁場発生器２により生体内の正常部分領域に対し
てはＨ（Ｘ、Ｙ、Ｚ）がＨ（Ｈ１又けＨ〉Ｈ２となるよ
う、又、悪性腫瘍領域に対しては、［１＜Ｈ＜Ｈ２とな
るようにする。この状態において周波数ｆが−Ｈ１＜
ｆ ＜、；−Ｈ２なる高周波磁場を靜２π
磁場に対して垂直に印加すると、悪性腫瘍領域において
のみエネルギーの吸収が生ずる。Expanding the above explanation three-dimensionally results in the following. First, the static magnetic field generator 2 is used to adjust H (X, Y, Z) for a normal partial region in a living body so that H (H1 spans H>H2), and for a malignant tumor region to [ 1<H<H2.In this state, the frequency f becomes -H1<H2.
When a high-frequency magnetic field with f<,;-H2 is applied perpendicularly to the quiet 2π magnetic field, energy absorption occurs only in the malignant tumor region.
［発明の他の実施例］
悪性腫瘍部分のより効果的なエネルギー集中を生じさせ
るために、電磁極や電磁コイルの多数化や°、それらの
平行移動、回転移動を行なわせる機能を付加することが
可能である。[Other embodiments of the invention] In order to more effectively concentrate energy in the malignant tumor area, a function is added to increase the number of electromagnetic poles and electromagnetic coils, and to move them parallelly and rotationally. is possible.
第１図は本発明の一実施例を示す図、第２図は本発明の
詳細な説明するだめの図である。
１・・・生体、２・・静磁場発生器、
３・・・高周波磁場発生器、４，５ 電磁石の極、６
・・・電磁コイル、７・・正常部分、８・・・悪性腫瘍
部分。
第 １ 図
第２図
俊ＩFIG. 1 is a diagram showing one embodiment of the present invention, and FIG. 2 is a diagram for explaining the present invention in detail. 1... Biological body, 2... Static magnetic field generator, 3... High frequency magnetic field generator, 4, 5 Electromagnet pole, 6
...Electromagnetic coil, 7.. Normal part, 8.. Malignant tumor part. Figure 1 Figure 2 Shun I
Claims (2)
発生させるための静磁場発生器と、被検体内空間に任意
の周波数で任意の強度を有する変化磁場を発生させるだ
めの変化磁場発生器とを備え、被検体内の特定の部分の
みにエネルギー吸収を起こさせうるようにしたことを特
徴とする核磁気共鳴装置。(1) A static magnetic field generator for generating a static magnetic field with arbitrary intensity distribution in the internal space of the subject, and a changing magnetic field for generating a changing magnetic field with arbitrary intensity at any frequency in the internal space of the subject. A nuclear magnetic resonance apparatus characterized in that it is equipped with a generator and is capable of causing energy absorption only in a specific part within a subject.
変化磁場発生器で発生される磁場とは互いに直交するこ
とを特徴とする特許請求の範囲第１項記載の核磁気共鳴
装置。(2) The nuclear magnetic resonance apparatus according to claim 1, wherein the static magnetic field generated by the static magnetic field generator and the magnetic field generated by the variable magnetic field generator are orthogonal to each other. .
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57178539A JPS5967971A (en) | 1982-10-13 | 1982-10-13 | Nuclear magnetic resonance apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57178539A JPS5967971A (en) | 1982-10-13 | 1982-10-13 | Nuclear magnetic resonance apparatus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5967971A true JPS5967971A (en) | 1984-04-17 |
Family
ID=16050242
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP57178539A Pending JPS5967971A (en) | 1982-10-13 | 1982-10-13 | Nuclear magnetic resonance apparatus |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5967971A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62194841A (en) * | 1986-02-20 | 1987-08-27 | 工業技術院長 | Local examination treatment apparatus by nmr |
| JPWO2018097185A1 (en) * | 2016-11-24 | 2019-06-27 | 公立大学法人横浜市立大学 | Cancer treatment equipment |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54158988A (en) * | 1978-05-31 | 1979-12-15 | Makudonarudo Sutoraku Jieemusu | Method of picking up image information from body |
| JPS5569044A (en) * | 1978-11-16 | 1980-05-24 | Emi Ltd | Inspection method and device using nuclear magnetic resonance |
-
1982
- 1982-10-13 JP JP57178539A patent/JPS5967971A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54158988A (en) * | 1978-05-31 | 1979-12-15 | Makudonarudo Sutoraku Jieemusu | Method of picking up image information from body |
| JPS5569044A (en) * | 1978-11-16 | 1980-05-24 | Emi Ltd | Inspection method and device using nuclear magnetic resonance |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62194841A (en) * | 1986-02-20 | 1987-08-27 | 工業技術院長 | Local examination treatment apparatus by nmr |
| JPWO2018097185A1 (en) * | 2016-11-24 | 2019-06-27 | 公立大学法人横浜市立大学 | Cancer treatment equipment |
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