JPS5967208A - Disinfectant composition - Google Patents

Abstract

PURPOSE:The titled composition that is obtained by combining trichloroisocyanuric acid with a combination of isocyanuric acid and magnesium oxide or hydroxide or with magnesium or calcium isocyanurate, thus showing increased storage stability with H<+> concentration inhibited from increasing. CONSTITUTION:The titled composition is obtained by combining (A) 100pts.wt. of trichloroisocyanuric acid (TCCA) with (B) a combination of 100pts.wt. of isocyanuric acid and 5-80pts.wt. of MgO or Mg(OH)2 or (C) 5-100pts.wt. of magnesium or calcium cyanurate. The resultant composition can prevent the hydrogen ion concentration from increasing in a closed aqueous system by continuous use of TCCA and is kept stably for a long period of time in the preparation forms of dust, granules, pills or tablets, even under wet conditions. The magnesium or calcium salt of cyanuric acid is preferably di- or tri-salt.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a disinfectant composition containing trichloroin cyanuric acid that prevents an increase in hydrogen ion concentration during use and has good storage stability.

Conventionally, compared to sodium hypochlorite solution or highly bleached powder (main ingredient secondary calcium hypochlorite), chlorinated incyanuric acid compounds have a stable active chlorine (residual chlorine) supplied to water, so less It is useful in a wide range of fields because it requires only a small amount of use, does not contain calcium hydroxide or calcium carbonate like highly bleached powder, is completely soluble, and has strong sterilizing power. A chlorinated isocyanuric acid compound containing 2% trichloroincyanuric acid (hereinafter referred to as TOOA) can be used as a disinfectant for wastewater, pool water, cooling water, etc., or as a slime control agent.
It is used in large quantities in the form of powder, granules, two tablets, etc.

However, TOOA is a closed water system with stored water 2
For example, when supplying stagnant water such as cooling water or pool water for sterilization and slime control, continuously or intermittently for a long period of time, TOOA may accumulate in the stagnant water and increase the hydrogen ion concentration. be. For example, this tendency is remarkable in water with low alkalinity such as rainwater. In addition, in water that is relatively easily contaminated, such as cooling water, residual chlorine is consumed quickly, and therefore the amount of TOOA supplied also increases, leading to an increase in the hydrogen ion concentration in the water. If the hydrogen ion concentration increases, equipment will be corroded, which is undesirable.

Therefore, in order to prevent the hydrogen ion concentration of the stored water from increasing, the solution is to regularly spray IJum (carbonate), but the pH is measured and the amount of sodium carbonate is gradually added. The method is complicated.

Research on preventing the increase in hydrogen ion concentration due to the continuous use of T(EOAi) in the above closed water system has not been conducted much, but in order to improve the solubility of TcCA or tahadichloroisocyanuric acid, Compositions containing alkaline substances have been proposed.

For example, it has low solubility in products commonly sold outside Japan (the United States), that is, its dissolution rate is slow.

By incorporating sodium carbonate, an alkaline substance, it is intended to speed up the dissolution rate and increase the elution of active chlorine from the water. However, the tablets are unstable when wet with water and emit nitrogen chloride gas, which is explosive. That is.

It must be handled with care, and storage is strictly prohibited.

In addition, Japanese Patent Publication No. 57-25004 discloses tablets containing trichloroisocyanuric acid as the main ingredient, with the intention of making the dissolution rate of TCOA more user-friendly. K)'i has been proposed, and the molded tablet disintegrates and disperses in water, but the stability of single tablets during storage is still low, and the decomposition of available chlorine and generation of nitrogen chloride are high. It's a trench.
It has very low stability when wet with water, which is not desirable.

As mentioned above, TCOA itself is highly reactive and is therefore unstable against most substances. .

With the aim of obtaining a composition with good storage stability, we conducted extensive research into the sensitive physical properties of TOOA and the mechanism of nitrogen chloride production, and surprisingly, we found that TOOA, which is extremely sensitive to alkaline substances, The present inventors have discovered that by blending a specific alkaline substance with incyanuric acid, or by blending a specific cyanuric acid salt with TCCA, an extremely stable blend can be achieved, leading to the completion of the present invention.

That is, 9 The present invention provides the following A) for 100 parts by weight of TOOA.
or B) A sterilization and disinfection characterized by blending A) 5 to 10 parts of incyanuric acid and 5 to 80 parts by weight of magnesium oxide or magnesium hydroxide.B) 5 to 100 parts by weight of magnesium salt or calcium salt of cyanuric acid. It is a drug composition.

When only magnesium oxide or magnesium hydroxide is added to ToCA, an increase in hydrogen ion concentration due to continuous use of TOOA can be prevented, but stability is poor during storage, especially when wet with water (humidity). , the generation of nitrogen chloride gas, etc. is significant. (See Comparative Example) However, magnesium oxide or magnesium hydroxide was often added alone to TCCAK, and incyanuric acid was also used in combination. The combination of three components not only suppresses the increase in hydrogen ion concentration in a closed aqueous system, but also provides an extremely stable composition even during long-term storage and humidity.

[7. 5 to 100 parts by weight of isocyanuric acid, and 10 to 50 parts by weight of magnesium oxide, and 5 to 5 parts by weight of magnesium hydroxide.
~80 parts by weight, preferably 5 to 50 parts by weight.

Of course, magnesium oxide and magnesium hydroxide may be combined at the same time. Outside the range of this formulation, i.e. T
Based on 100 parts by weight of CcA.

If incyanuric acid is less than 5 parts by weight or if magnesium oxide, slaked or magnesium hydroxide is mixed in more than 80 parts by weight, long-term storage and wet stability will decrease; If the amount of magnesium oxide salt and magnesium hydroxide is more than 5 parts by weight or less than 5 parts by weight, the increase in hydrogen ion concentration in the closed water system due to TCOA cannot be suppressed.

By using magnesium salt or calcium salt of cyanuric acid for TOOA as a convenient formulation, it is also possible to suppress the increase in hydrogen ion concentration in a closed water system caused by TOOA.

The magnesium T4 or calcium salt of cyanuric acid used in the present invention can be produced by various methods. This is a γL product obtained by reacting a slurry at room temperature. The resulting salt of cyanuric acid can be converted into a monosalt CM(OtN+0s)Is)x, depending on the molar ratio of isocyanuric acid and the corresponding oxide or hydroxide.
M u Ca also fiMgf], di-salt CM* (
C+N+O+H)z 〕+ )ri salt [M+ (C+ N
*O*L] is obtained. Di- and tri-salts are preferred for use in the present invention. 5 to 10 parts by weight of fiU, TccA in which magnesium salt of cyanuric acid or calcium salt of cyanuric acid is blended with TOOA.
0 parts by weight, preferably 1 to 6 parts by weight.

Of course, it is okay to use the calcium salt of cyanuric acid and the magnesium salt of cyanuric acid at the same time. Outside the range of this formulation, i.e. 5% by weight of magnesium salt or calcium salt of cyanuric acid based on the weight part of TcoAloo.
Below.

TOOA increased the hydrogen ion concentration and reduced it.
If it is more than 0 part by weight, it is not stable when wetted with water, that is, when wet, and the generation of nitrogen chloride increases, which is undesirable. It goes without saying that a calcium salt or a magnesium salt of cyanuric acid should be added to the composition of isocyanuric acid and magnesium oxide or magnesium hydroxide for the TOOA described above.

As described above, even when the blended compositions a and 'rcaA of the present invention are continuously supplied for a long period of time in a closed water storage tank, the increase in hydrogen ion concentration can be suppressed, and the blended composition is stable. It can be saved to . The combination composition is in its initial state.

It may be in any desired dosage form, such as particulates or two round tablets, and additional excipients such as binders, fluidizers, and lubricants, and auxiliary agents such as disintegrants may be added to the granulation. A filler may be added to adjust the concentration as appropriate.

The present invention will be described in detail below with reference to Examples and Comparative Examples, but the technical scope of the present application is not limited thereto.

Example 1 TOOA with a particle size of 50 to 350μ and a water content of 021%,
70 parts by weight and 2 particle diameters of 20-200μ.

A powder composition was prepared by uniformly mixing 20 parts of cylinuric acid with a water content of 0.19% and 10 parts by weight of magnesium oxide (trial grade), and the following evaluation tests were conducted.

Evaluation test (Δ) Evaluation of hydrogen ion concentration; Take the amount that makes the presence of TC (EA) in the formulation 50,
Add to this t) H7,32,M alkalinity (value calculated by converting the total amount of carbonates, etc. contained in water into calcium carbonate by using methyl orange as an indicator and a strong acid) 32 m9/l of tap water After adding 1 t of water and stirring for 1 hour, the aqueous solution was added.

After being left at 65° C. for one week and most of the residual chlorine decomposed, pH' (r) was measured using an OH meter.

The results are shown in Table 1.

(B) Evaluation of storage stability; Internal volume 500mI! A 10th container containing 202 containers of mixed powder is sealed with a rubber stopper in a three-way glass container, and valve-sealing glass stoppers are attached to the 20th and 30th containers to close the container.
It was stored stationary in a constant temperature bath at 35°C for 20 days. Then the second
Connect the conduit for dry nitrogen gas to No. 0, and connect the conduit leading to the 100g (1% ol) l-IJ resin bath solution to No. The decomposed gas generated and accumulated in the container is absorbed into the orthotolidine solution, and the degree of coloring of the bath liquid is adjusted to a wavelength of 440.
The amount of generated decomposition gases (chlorine, nitrogen chloride) was determined by measuring the absorbance of yellow light at 10 nm using a full spectrophotometer. The results are shown in Table 1.

(C) Evaluation of wet stability; 101 powders were added to an Erlenmeyer flask with a stopper and an internal volume of 5Qa7.
Enter. The water is drained 1ornI! Pour it on the surface of the end,
The container was sealed tightly and stored in a constant temperature bath 1 at 65° C. for 15 minutes, then opened, and the gas produced in the solution was determined by a sensitivity test. The results are shown in Table 1.

Examples 2 to 5 and Comparative Examples 1 to 9 The compositions shown in Table IJ were combined in the same manner as in Example 1 to form powder formulations and as in Example 1.

An evaluation test was conducted.

We also evaluated the powdered formulation in tablet form. For tabletting, add powder to 30 mm f or 25 mm f,
Rotary tablet press produces approximately 400 cr/crl pressure.
A continuous tablet compression method was used from Vc. In this way, diameter 30 ya i, thickness 17M1 weight 202 or diameter 2
A cylindrical tablet with a length of 5 mm, a thickness of 12 mm, and a weight of 9 mm was made.

Tablet No. 202 was used for evaluation of storage stability. Tablet No. 202 was used for evaluation of wet stability.

Table 1: 1) OA; Cyanuric acid 2) ◎; After opening the bottle, the odor is extremely weak or barely noticeable.

O; There was a slight pungent odor after opening the bottle.

L; There was a strong pungent odor after opening the bottle.

△　;　There is no yellow color inside the flask.

There is a pungent odor similar to that of a closed bottle.

×; The inside of the flask turns yellow due to significant generation of 2 decomposition gas during storage.

As shown in Table 1, TOOA, cyanuric acid.

With the three-component system of magnesium oxide or magnesium hydroxide, the decrease in U and pH is small, that is, the increase in hydrogen ion concentration is small, and the stability of each powder tablet is high. T.O.
Although stability is high with OA alone, a decrease in pH is observed. Furthermore, when only cyanuric acid is added to ToOA, T.

The trend is similar to that of OA only.

On the other hand, TOOA contains alkaline substances (Na, co, )
When 'jz is blended alone, the decrease in p)I can be suppressed, but the storage stability and wet stability are extremely reduced.

It is dangerous if it gets wet with water during storage.

Furthermore, even in a combination of six ingredients: TOOA, cyanuric acid, magnesium oxide, and magnesium hydroxide, cyanuric acid is extremely low.

If the amount of magnesium hydroxide is too large, the stability will decrease in either case.

Examples 6 to 1o and Comparative Examples 1o to 16 With the compositions shown in Table 2, powders were uniformly blended in the same manner as in Example 1, and two tablets were made for evaluation.

The results are shown in Table-2. Similarly, the magnesium, calcium and sodium salts of cyanuric acid used were obtained as follows.

Magnesium salt of cyanuric acid; 1 mol of isocyanuric acid, particle size 2o~200μ, water content 0.19%, magnesium hydroxide powder (first grade reagent)
1.5 mol was added to 2 tons of water, reacted in an aqueous slurry system, and dehydrated and dried.

Free moisture 15% (crystal water 8%) Particle size 40-150
μ Calcium salt of cyanuric acid; 2. Magnesium hydroxide was replaced with calcium hydroxide, the reaction was carried out in the same manner, and the product was dehydrated and dried.

Free moisture 1.2% (crystalline water 14%) Particle size 40-15
0 μ Sodium salt of cyanuric acid: 1 mole of the above isocyanuric acid and 3 moles of sodium hydroxide were added to 6 tons of water, reacted in a homogeneous aqueous system, crystallized by cooling, and obtained by dehydrating and drying.

Free moisture 1.5% Particle size 20-150μ Table -2 1) (!A-Mg + Magnesium salt of cylindrical acid 2
) ('!A-Oa ; Calcium salt of cyanuric acid 3
) 0A-Na; Sodium salt of cyanuric acid 15- Table 2 shows 'l' as shown in Pos. When COA, magnesium salt of cyanuric acid, or calcium salt of cyanuric acid is used, As shown in the comparative example, when the sodium salt of TOOAK cyanuric acid is blended, although it has the effect of suppressing the pH drop, it is found that the stability decreases. Alternatively, even if the calcium salt of cyanuric acid is used in an extremely small amount, the stability is good, but it is not possible to suppress the pH drop.

On the other hand, excessive blending reduces the stability of To('!A).

Patent applicant: Nissan Chemical Industries, Ltd. 16-

Claims (1)

[Scope of Claims] 1. The following A) or B) based on 100 parts by weight of trichloroin cyanuric acid A) 5 to 100 mt parts of isocyanuric acid and 5 to 80 parts by weight of magnesium oxide or magnesium hydroxide B) Cyanuric acid A sterilizing disinfectant composition comprising 5 to 100 parts by weight of a magnesium salt or a calcium salt of an acid.