JPS5953425A - Vaginal lubricant - Google Patents

Abstract

PURPOSE:To provide the titled agent useful for the normalization of the microbial flora in vagina and the humectation and lubrication of vagina, by using whey or its treated material as an active component. CONSTITUTION:The agent contains whey or its treated material as an active component. The bacteria in the vagina are composed mostly of doederlein vaginal bacili having the physiological protective mechanism and the self-cleaning activity to protect the upper genitalia from infection with bacteria; however, the microbial flora in the vagina sometimes becomes to an undesirable state after menopause, etc. Further, a mucous liquid is secreted in the vagina generally by the effective sexual stimulus to facilitate the coitus; however, one may feel the difficulty, etc. in the coitus by the insufficient secretion caused by various external conditions and age, etc. It has been found that whey is effective for the normalization of the microbial flora in the vagina and the humectation and lubrication of the vagina. The whey includes any wheys such as the one obtained by adding an acid to milk, and separating the coagulated product. The prepared whey is absorbed in a tampon, and used as an insertion agent.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to an agent effective for vaginal cleansing or moist digestion.

More specifically, the present invention relates to a vaginal moisturizing lubricant containing poei or a processed product of poei as a sexual component.

In general, ovarian hormones are involved in the metabolism of vaginal wall dryness,
In particular, the mucous membrane of infants and young children who are in a state of sexual quiescence, which is controlled by nistrogien, is thin, and when the sex hormone I'i'i movement during puberty becomes active, the thickness of the men's cortical layer becomes less than 1 thick.
After sexual maturation, if enough nistrogien is secreted, the vagina becomes naturally protective.
It not only keeps the vagina juicy and healthy, but also prevents the growth of 14 pathogenic bacteria in the vagina. )'s thin+'tT
It has the effect of subtracting 1ν and preventing it. This is my vagina r7
+Made L1. This means that during sexual growth, the skin of a disabled person thickens and at the same time contains dalicogen in the epithelial cells, but the amount of glycogen in the exfoliated epithelium is 4J7! The decomposition product J is the decomposition product J, and lactic acid is produced by the action of intravaginal bacteria.
& increases, which favors the growth of non-pathogenic Daederlein's microorganisms, and ultimately kills 4.1 microorganisms and pathogenic microorganisms.

According to Bergey's Manual (194B), this bacterial group includes Bacillus vaginae.
, H, vaF tal is -1o+g+s,
H,vp)<1nalis.

Ac 1dol) aCteriu+n doederl
i++ic, Lactobacillus
-t18+Ierlein.

L., acidophylns, etc. were said to be included.

In 1960, 1GO8A investigated the vaginal bacteria of 21 insecure women [7, 65 strains of Lactobacillus 1'if[1~,
As a result of classifying 21 of these stocks (remaining 14 stocks V1
death i), 14 strains are Lacidol + hilus, 2
The other is IJ, CRRelvar rb+nunn8us
, 4 strains were L-formcnti, 1 strain.

From the fact that celloMos++s -Ca-), Dede, lreline vaginal rod bacteria, acidoi+hi
lus f: It was assumed that the main ingredient was lactic acid. (J
, gen, IVHcrnhiol 25197)
It was, Bt! This is also adopted in the 8th edition of rgey's Marmal.

In this way, +j in the vagina, lll l! j is mainly occupied by this Daederlein IFn rod, or
Only 110 non-Chihei native bacteria were mixed in.

Furthermore, at birth, intravaginal r [sterile, but in a short period of time]
After the infiltration of the page, after 2 to 6 weeks, it changes to Daederlein's bacteria group, and then, at the age of puberty, cocci, streptococci, coryneformes/cacteria, etc.
＋慴 etc. are added, and these are dominantly proliferating. Before menarche, these two phases undergo a gradual change [7], and lactobacillus α4 becomes predominant, then dark blue, then stencil, and infection-protective factor 1.
It will be more useful than ever.

Reprimand 1. Therefore, when Nishiki enters menopause L 1, it changes again, and changes to a mixed phase containing cocci and continuous button-shaped bulbs, just like in Sishoma.
, in the history &-, 1-, lk' (inner may become unfavorable four-phase °C).

-: jj R”
i', 'F Before the increase in psychogenic impotence due to K,
Is it because of interest in sexual medicine?

In general, if effective sexual stimulation is added, fLlj gap, viscous in the liver? l't tlk is divided into a sex act in a circle t1t
However, its viscous line is similar to that of the Bartholin gland, which fulfills its seventh function.
``Tsu Jl / (1, However, according to recent findings, Bartholin l'l J: Ri's secretion 1.1-4 M +
At the 2nd degree, the main character is the dilation of the veins surrounding the vagina and the exudation of I7 from it.
) 11 has arrived.

However, due to various external factors, age, etc.
l Difficulty in performing IIF acts due to lack of secretions during excitement, It
('4: Don't do it, there's a new problem] It's been a long time since I've had a problem.

The present inventors sought to royalize the bacterial flora in the vagina and reduce the amount of moisture in the vagina.
By using the treated product as an active ingredient, I'
l'l'? , 1.1. 'I was able to say J.

The present invention also uses whey 17<Hazonodokoro1jl! The whey used in this product is the whey obtained by adding acid to milk and dividing the coagulate. It contains all kinds of poei, such as whey that is separated by adding rennet to milk for t1Σ and coagulating it, and whey that is obtained by culturing lactic acid bacteria in milk and separating the coagulated product.

In the case of adding acid, add 1M acid, lactic acid, etc. to milk and make it expand to about pII = 4.6. If you leave it for a while, k<iJs will precipitate, so use the supernatant as whey. Can be separated.

In the case of 65% net/net, add 1,000,000 units of rennet to milk heated to about 50°C and add several al/kg of black]t
! In addition, for 1 to 6 hours, the aggregates precipitate and can be separated as whey.

Add each milk starter to milk (incubate at 25-65°C,
+l (= 5.2) As the curds congeal, it can be separated to obtain whey. (Special) (Among lactic acid bacteria, Lactonocylus nigriti black 85
1. When using li"ER+vl PA5851, the fermented milk becomes viscous, so it is not necessary to add a thickener, and excellent whey can be obtained.

The whey obtained in this way can be used as it is, but it can also be treated with , history, e, 1, jin's component power 11 can be calculated.

In the proteolytic enzyme treatment, 1) 11 of whey is 4~
5, so for example, Proctorbi (Meiji Seika),
+lbt Iqv i' such as Morsin (Kusshin Mulberry)!
i;, 1 It is preferable to use a white matter digestive enzyme agent. these"
・Very few moments during h drafting 11 poei, for example 5~i o
o my% culm 1 (cold JJn L), if heated to about 55 to 55°C, the protein will be separated for about 5 to 20 hours.

By enzymatic decomposition, proteins are reduced to 1111 low-molecular-weight butide and L-amino acids, resulting in data-y' tr
y line + I'l'r is good for the growth of bacteria (its level is out of honor 3, it is broken, and generally the protein's filtrate is
11. +'(The suction from the wall is 11 t1 stronger, so 41(
It is also effective in preventing allergies caused by white υl. In addition, if albumin or clopurine, which is a member of the 11'11'-membered solution, remains in the final process, thermal condensation f,!,J will occur. In this way, it is preferable to adjust the osmotic pressure of whey or e1 whey treatment. The osmotic pressure of serum is 275-290 mOsm/L, but in this city it is 300-40 mOsm/L, considering that it is diluted in the vagina.
DrnOsm/'tlA# is i-approved.

For whey or whey processed products, add carbohydrate-based thickeners such as CMC, sl/lium alginate, etc., and reduce the viscosity to 150-6.
I like that it can be adjusted so that it becomes a 0D cps culm.

iu・'J' You can use it as a go-between by adding it to an IP V1 tampon, or you can use it to increase your hunger and apply it to 11, or you can put it in a capsule and use it for sitting.

(I do not show the actual implementation of this book.

Fruit 61ij l tari milk, detltr 'i'1. Shift Bacillus niculutii A 851 cultured in FM-pulled? M-PA
5 (added 10% starter of 451 and heated at 1°C at
0 hour drunkenness 1 degree "Cultured ribs, centrifuged minute Pri#shi, approx. 50
% of whey at 11v rate.

The obtained poei was kept at 50°C (,7,15h72≠
Side 1 Add acidic proteolytic enzyme agent (Septilysine) to TA port + u
I-,.

At 3:11, I worshiped the old 1 and disassembled it.

1-. Treat the treatment solution for 15 minutes.
F. Rooster (((Inactivated), added lactose to this Jl, and poured it so that the permeation piece was 3511tn (,) S 171 /ノ.

f4 x? in1.1j17,1 C~ic -N
Add 1.5% of a and press well 4 times (done - 1: viscosity 11 (200 raps)) N-Soup dispensed into a thermoplastic container and autoclaved at 121℃: 155jitillII2
The fungus is 1, and the 11 is 1, and the 1 is 1: again.

Claims (1)

[Claims] Retsuyu f1' containing whey or its processed product as an active ingredient
l: l lubricant 0