JPS5935147A - Automatic analyzer - Google Patents

Abstract

PURPOSE:To save labor eliminating constant monitoring with a warning given by calculating the initial capacity of reagents from several different reagent containers, the quantity per one distribution, the frequency of distributions per hour and the quantity of residual reagent from the operation time beginning with the reaction start time in an automatic analyzer. CONSTITUTION:Reagents are distributed into a number of reaction tubes 2 from a plurality of reagent bottles 5 with respective pumps 6 in a reaction line 1 on which the reaction tubes 2 are arranged along a endless drive belt at an equal pitch and a photometric analysis or the like is done. Prior to this, a CPU 9 memorizes the initial capacity of respective reagent bottles a1, a2...an, the quantity per one distribution and the frequence of distribution per hour. A drive section 7 of a line 1 is operated with the action of a start switch at an input section 8 and the quantity of residual reagents in the reagent bottles a1...an is calculated from the passage time after the operation start time to determine the continuously measurable time whereby a warning is generated at an output section 10 by a display, a voice or the like. This can reduce the burden on an inspection engineer to allow a quicker preparation for measurement thereby enabling efficient operation of the equipment.

Description

DETAILED DESCRIPTION OF THE INVENTION [Technical Field of the Invention] The present invention relates to an automatic analyzer that automatically analyzes a large amount of specimen using one or more types of reagent sounds.

[Technical background of the invention and its problems]

Conventionally, automatic analyzers, such as automatic biochemical analyzers, sequentially sample one or more reagents and
This automatically performs a large number of analytical measurements by injecting the sample as it moves along the entire reaction line at a predetermined cycle time. In analytical measurements, reagents are selected according to the analysis item and stored in the reagent storage in the automatic analyzer.The amount of reagent dispensed is determined by setting the stroke of the syringe in advance to sample a predetermined amount. Set so that the rows are displayed.

As the reaction line operates, the number of reagents stored in the reagent storage decreases in proportion to the line operating time, but conventionally, while the reaction line is operating, it is difficult to determine how many hours the line will continue to operate depending on the amount of remaining reagent. There was no automatic analyzer available to recognize whether or not the product could be stored. For this reason, while the line was running, it was up to the operator to visually check whether there was any reagent left in the reagent storage or how much longer the twin could continue to operate depending on the amount remaining. . However, since the amount of reagent discharged differs depending on each analysis item, it has been difficult to visually check the remaining amount of reagent and calculate the total amount of continuous operation time of the line thereafter. Therefore, the operator is forced to frequently check the remaining amount of reagent and is burdened with having to be constantly careful while the line is in operation.

[Purpose of the invention]

The present invention has been made in view of the above-mentioned circumstances.It is an object of the present invention to provide an automatic analyzer that allows an external party to recognize the operating time of a line that can be continuously measured based on the remaining amount of reagent while the line is in operation. This is the purpose.

[Summary of the invention]

The outline of the present invention for achieving all of the above objects is to provide an automatic analyzer in which all reagents stored in a reagent container are sequentially dispensed into a reaction line in a predetermined dispensing cycle for analysis and measurement. An input section for inputting the initial set amount of , one-time dispensing amount and two-dispensing cycle as parameters corresponding to the reagent, and an input section for inputting the initial setting amount of , one-time dispensing amount and two dispensing cycles as parameters corresponding to the reagent, and the input section that measures the time from the start of the reaction line operation and sequentially based on the measured time and the above parameters. Calculate the operating time that can be continuously measured based on the decreasing remaining amount of reagent C
The main feature of this device is that it has a pU, and an output section for inputting the output of the CPU and for making it externally recognized.

[Embodiments of the invention]

Hereinafter, one embodiment of the present invention will be described with reference to all the drawings. FIG. 1 is a schematic explanatory diagram of an automatic biochemical analyzer that is an embodiment of the present invention. In FIG. 1, reference numeral 1 denotes a reaction line, in which a large number of reaction tubes 2 are arranged at equal pitches on, for example, an endless drive belt, and are moved intermittently at a speed corresponding to each analysis item. 6 is a reagent nozzle, and the reaction line 1
A predetermined amount of reagent is completely dispensed into the reaction tube 2. Reference numeral 4 denotes a reagent storage, in which a plurality of reagent bottles 5 are installed. The temperature of the reagent storage 4 can be adjusted to prevent deterioration of the reagents. In addition, αl, α2. ... (Zn each indicates a different type of reagent. 6 is a reagent bonder, and a plurality of them are provided corresponding to each of the reagent bottles 4. The reagent sucked by the K-ko pump B is transferred to the reagent nozzle 3. It is designed to be discharged into the reaction tube 2 through. 7 is a line, a drive part,
The reaction line is driven, the reagent pump 6 is driven, etc.

8 is an input section, which has all the start switches of the line drive section 7, and inputs information such as the initial set amount of reagent into the reagent bottle 5, the amount of one dispensing amount, and the public order cycle for each reagent. It has 4 functions. 9 is a CPU, and the input section 8
It has a timer for measuring time from the activation of the start switch, and uses the information from the input section 8 and the timer to calculate and output the operating time of a line that can continuously measure the remaining amount of reagent. do. 10 is the above C
This is an output section for inputting all the outputs of the pU9 and for making the entire one hour of continuous operation of the line visible to the outside.

The operation of the automatic biochemical analyzer configured as above will be explained along the flowchart shown in FIG. 2.

First, before operating the start switch of the input section 8, the following information must be input to the CPU 9 via the input section 8.0 If the measurement item uses reagent αzk, for example, the reagent bottle Reagent αl to 5
The initial setting amount h (μt) is one dispensing cycle 'l (times/hour), and the amount of one dispensing d1 (μt/time). this house,
The initial set amount of reagent αl can be set to a constant amount according to the capacity of the reagent bottle 5 regardless of each reagent α1 to αl, but the dispensing cycle C1, one dispensing amount d1 is equal to the amount of reagent αl. This is a unique setting value for each type of reagent, and it usually differs depending on the type of reagent. The above parameter values are stored in the CPU 9K via the input section 8. After that, routine operation is performed. When all the start switches of the input section 8 are turned ON, each drive section is actuated via the line drive section 7, and the routine is started. When the reagent αl is activated, it is sucked in and discharged in a fixed amount one by one into the reaction tubes 2 that move sequentially through the reagent nozzle 3. On the other hand, in C and pU9, the remaining amount of reagent α1 is continuously decreased based on the parameter values and the time information of the timer. The possible operating time is calculated.The action of the above-mentioned CpU9 will be explained with reference to the flowchart in FIG.
It can be expressed by the following equation (1) using the operating time TrJd that can be continuously measured based on the remaining amount of 1, the parameter values A, CI, 4, and the time information t.

In formula (1), the numerator represents the remaining amount of reagent αl, and the denominator represents the amount of reagent consumed per hour. The calculation of the equation (1) in the CpU 9 is performed according to the flowchart shown in FIG. The continuous operation time Tr calculated by the CPU 9 from the remaining amount of the reagent αl is outputted via the output unit 8 so as to be recognized externally. Examples of this method include displaying the time on a display one by one, making a voice announcement at predetermined time intervals, and emitting a buzzer with a different tone at predetermined time intervals. By using any of the above methods, a laboratory technician can recognize information on the amount of remaining reagent in a time-sensitive manner. Therefore, the burden on the laboratory technician of constantly considering the remaining amount of reagents can be greatly reduced.

It goes without saying that the present invention is not limited to the above-mentioned embodiments, but includes all various modifications within the scope of the gist of the present invention. Although the above embodiments have been described using biochemical analysis as an example, the present invention can also be applied to other fields where automatic analysis is performed continuously. In addition, when using all two or more types of reagents for one analysis item, input the information of each reagent into the input section 8, and calculate the continuous operation time T based on the above formula (1).
All that is required is to calculate r and display it individually on the output unit 10.

〔Effect of the invention〕

As described above, according to the present invention, it is possible to provide an automatic analyzer that allows an operator to recognize information on the amount of remaining reagent in a sense of time. Therefore, even when the line is running, the operator can always check the remaining amount of reagent. The burden of consideration, etc. can be greatly reduced.

[Brief explanation of the drawing]

Fig. 1 is a schematic explanatory diagram of an automatic biochemical analyzer that is an embodiment of the present invention, Fig. 2 is a flowchart for explaining the overall operation of the embodiment, and Fig. 3 is a flowchart for explaining the entire operation in the CpU. It is a flowchart. 1... Reaction line, 2... Reaction tube, 3...
Reagent nozzle, 4... Reagent storage, 5... Reagent bottle,
6... Reagent pump, 7... Line drive unit,
8...Input section, 9...CPU, 10...
・Output section. Agent Patent Attorney Kensuke Chika (and 1 other person) No.
3 Figure-231-

Claims (1)

[Claims] Reagents stored in reagent containers? In an automatic analyzer that sequentially dispenses into a reaction line in a predetermined dispensing cycle for analysis and measurement, the initial setting amount of reagent to the reagent container, the amount of one dispensing amount, and the two-dispensing cycle are set according to the parameters depending on the reagent. A CPU that measures the time at the start of the reaction line operation and calculates the operating time that can be continuously measured based on the sequentially decreasing amount of reagent remaining based on the measured time and the above parameters. An automatic analysis device characterized by having: an output unit that inputs the output of the CPU and causes the output to be recognized externally.