JPS59231012A - Low pollution antiperspirant stick - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to an antiperspirant stick (a soft solid in the form of a stick similar to a "stick") composition. An antiperspirant stick containing isosorbide.

Antiperspirant formulations in stick form are rapidly becoming one of the more popular uses for active antiperspirants. In developing this product, several criteria regarding consumer satisfaction must be kept in mind in order to be successful in product sales. Above all, what it must have when applied to the skin is a pleasant feeling.

The next important feature that this product should exhibit is low staining potential for smearing on clothes.

The contaminating nature of antiperspirant products is a long-standing problem that the industry has been grappling with. This is universally defined as the level of difficulty with which antiperspirant stains (contamination) on fabrics can be removed using a standardized wash test.

One form of antiperspirant stick that has achieved a significant degree of satisfaction is a so-called suspension type product. In products of this type, waxy substances such as stearyl alcohol are used as excipients (vehicles) in which the active antiperspirant substance is suspended in the form of solid microparticles, usually as a powder. These products are excipient 7￥Il
f: Manufactured by heating to the molten state and then adding solid particulate antiperspirant. The molten product is poured into molds and allowed to cool.

Although a product formulated as described above meets the minimum requirements for an antiperspirant stick, it is unlikely to be acceptable for commercial purposes. For example, such products have an unpleasant waxy (slick) feel when applied to the skin. Moreover, there is a quick effect of this type of stain on the skin and hair in the area where it is used.

In an effort to overcome these problems, the prior art has proposed suspension-type antiperspirant sticks, aX products, containing all water-insoluble emollients. One type of material that is highly recommended for this purpose is newspaper volatile silicones, such as cyclomethicone.

Although the waxy feel and odor characteristics noted above with the use of volatile silicones have been greatly altered, this has been achieved at the cost of an overall increase in the staining potential of the product. However, if substantially all of the volatile silicone is replaced with a bathable emollient such as dimethyl isosorbide, there will be no increase in the staining potential of these antiperspirant sticks. It has now been discovered that touch and quickness can be eliminated. Moreover, the antiperspirant stick of the present invention is a non-greasy and effective product. Furthermore,
Since dimethyl isosorbide is neither a primary irritant nor a skin sensitizer, the antiperspirant sticks of the present invention are less likely to cause irritation.

Accordingly, it is an object of the present invention to provide an antiperspirant stick composition that does not have a waxy feel or exhibit fast-acting characteristics, and furthermore has less chance of smearing (low staining). is the primary purpose of It is a further object of the present invention to provide an antiperspirant stick of the above character which is non-sticky and an effective antiperspirant. Furthermore, it is a further object of the present invention to provide an antiperspirant stick having the aforementioned characteristics that is also less irritating. Other and more detailed objects of the invention will become apparent from the following description and claims.

As pointed out above, an essential feature of the present invention is the incorporation of water-soluble emollients, and in particular dimethyl isosorbide, into the antiperspirant stick composition. Dimethylinrubide is a non-volatile, non-greasy, water-soluble, still boiling liquid. It is virtually inert and compatible with many organic substances. Therefore, it can be easily incorporated as a component of an antiperspirant stick composition without worrying about interactions with other components of the stick. This substance has the structural formula: and is available on the market.

Dimethyl insorbide is the preferred water-soluble emollient useful for purposes of the present invention, although other water-based emollients can also be used. Examples of such other water-soluble emollients include: It is possible to show:
Alkylene polyhydric alcohols such as propylene glycol, ethylene glycol, diethylene glycol, ethylene glycol) and some other glycols such as higher polyethylene glycols, with the general formula: (where α has an average value of 2 to 33) , and b is 3
A water-soluble compound (with an average value of 45 to 45) (HB series Ucon, manufactured by Union Carbide), a random copolymer made by the reaction of ethylene oxide and propylene oxide at various Hell ratios. (45H series Neecon UCOn], Union Carbide), for example [where 2 and y are all numbers and 2R is a fatty alcohol moiety (e.g. cetyl, myristyl, stearyl), 2 The value of can range from 3 to 10, and 1
[values can range from 2 to 50] Procetyl AWS (Exoda CEzoda), a block co-MMF ether of polyoxypropylene, polyoxyethylene, referred to as Pluronic, is a long-chain fatty alcohol.

Bathing emollients, and in particular dimethyl isosorbide, typically constitute an important part of the antiperspirant stick products of the present invention. Generally, it will constitute about 15 wt% or 20 wt% to about 50 wt% of the total weight of the stick composition.

In a preferred case, this range is on the same coulometric basis (from about 35.0 wt% or 40 wt% to about 50 wt% of the total).
% or 60.0wt%.

The remaining portions of the antiperspirant stick compositions of the present invention can be configured similarly to the remaining portions of the American antiperspirant stick compositions of the suspended temperature type, i.e., the antiperspirant stick compositions of the present invention. Approximately 100 for the shaping part? to 15
0? It is possible to use a low melting point waxy material, which is a waxy material with a melting point of .

Typical suitable low melting point waxes are fatty acids having about 8 to about 22 carbon atoms, fatty alcohols having about 8 to about 22 carbon atoms, silicone waxes, and glycerol monostearates. Particularly useful substances of this type are Cs Cm fatty acids and cs cn fatty alcohols. -The following can be given as an example:
namely, cetyl alcohol, stearyl alcohol, myristyl alcohol, lauryl alcohol and behenyl alcohol. However, a preferred low melting wax is stearyl alcohol. The amount of low melting wax that can be included in the antiperspirant stick compositions of the present invention can also vary to a large extent.

Typically, this material will be about 8.8% of the total weight of the composition. Owt% to about 35.0wt%, and preferably about 16.011)t
% to about 27.0 wt%.

An amount of water-insoluble high melting wax can also be included in the antiperspirant stick compositions of the present invention to help provide the base structure of the stick. Approximately 150 waxes are suitable for this purpose? It is a water-insoluble wax with a melting point below about 215 to about 215. Suitable waxes include carnauba wax, beeswax, spermaceti wax, paberry wax, Condelia wax, Montan wax,
There are odor waxes, ceresin, paraffins, synthetic waxes and microcrystalline waxes and mixtures thereof. These range from about 5 wt% to about 1 wt% of the total weight of the stick composition.
In a preferred stick comprising 0 wt%,
This accounts for about 2.0 wt% to about 6.0 wt'X.

In order to achieve and maintain a more uniform distribution of the powdered active antiperspirant in the stick compositions of the present invention, so-called "waxy gelling agents" can be used.

These are described in some detail in columns 2 and 3 of U.S. Pat.
Included are materials such as 00 Wax, Paraffin Wax 130'/135 Lower, 195 White Wax, Victory White Wax and Himalti Wax 180M and mixtures thereof.

This material is generally about 0.5 of the total weight in the stick.
wt% to about 10.0 wt%, with preferred amounts ranging from about 2 wt% to about 5 wt%.

The main active ingredient of the antiperspirant stick composition of the present invention is, of course, the antiperspirant. This usually takes the form of an astringent aluminum or zirconium compound or a mixture thereof; ie a mixture or complex of aluminum compounds or a mixture of zirconium compounds or a mixture of aluminum and zirconium compounds. Usually the aluminum or zirconium compound will be in the form of an astringent salt.

Typical antiperspirant active ingredients include finely divided aluminum chlorohydroxide and aluminum hydroxybromide, aluminum chloride, aluminum-zirconium polychlorohydrate complex, and 1
Included are the antiperspirant actives disclosed in U.S. Pat. No. 3,792,068 to Lll Ledders et al.

This patent of Lwedders et al.
, (where X is an anion selected from the group consisting of chloride, certain oxide, and iodide, and m is a number from about 0.8 to about 1.2): Y is an anion selected from the group consisting of 10 toIi) C1l and 0CII, and n has a value of about 0.16 to about 1.2; (3) the p part, glycine, dA;
-1-lyptophan, dl, -β-phenylalanine,
A neutral amino acid selected from the group consisting of dl-valine, dl-methionine and I-alanine, where p is about 0.
B. co-dissolving in water B. the resulting mixture at a temperature of about 100° C. to about 230° C. and a moisture level of about 0.5 wt% to about 15 wt%; and grinding the resulting dried inorganic-organic antiperspirant complex into a fine powder form.

A preferred aluminum compound in the process of LlLeddtprs et al. is aluminum chlorhydroxide of formula A4(OR)sC12HtO. LlLe
A preferred zirconium compound in the method for producing d, d e r s, etc. has the formula Z r O(OB ) C1l 3&0
) is zirconyl hydroxychloride.

The preferred amino acid for the preparation of the conjugate of Luedders et al. is glycine of 2C:fb (MB2) C00H. Salts of such amino acids can also be used in such antiperspirant complexes.

The aluminum-zirconium polychlorohydrate complex that can be contained in the stick composition of the present invention has the general formula: (cL) z is a number from 2 to 10: (6) z
is a number from 3 to 8; is a number from 3 to 3, and y typically has a value of from about 5 to about 29.

As will become clear from 2), glycine may be bound in the complex or may be absent. The presence or absence of glycine in the complex increases the amount of unbound glycine or pE to a level of about 2.5 to about 45 or to a preferred pH of about 2.8 to about 3.8. It will depend on the amount of buffer that can be included in the composition. A number of aluminum-zirconium polychlorohydrate composites are known in the prior art that are useful for the purposes of the present invention. - As an example, the following can be shown along with the empirical formula: Nialuminum zirconium tetratalolobidrate (#4Zr (OE)stclk);
Zirconium tetrachlorohydrate glycine (W
icktnoL +E-369) (AA!4Zr (
OR), 2clI4-NIlxCHxCOOH):
Fluminirum Zirconium Trichlorohytre)
(A＾Zr(OH)hsclls) ” Aluminum Zirconium Trichlorohydrate Glycine (A＾zr(oH),3C1l,・NIf2C
& C(j OH) ; Aluminum zirconium pentachlorohydrate (A). Zr (OR')
Aluminum zirconium pentachlorohydrate glycine (AA4 toZr (O
H) 29C1l 5 ・NHtCBb COOH)
; 7 k mini') Mu Zirconium octachlorohydrate (Al16Zr(OR) 14c1g)'
Aluminum zirconium octa-10 lobidrate glycy:'(AAaZr(OH) 1406g ・N&
CH2C0011). The aluminum-zirconium polychloroidolate complexes each contain ACH and A13CA! It can be mixed with s.6H20 in various proportions in solution or in powder form.

The U.S. Government (Food and Drug Administration) Antiperspirant OTC Panel has adopted certain nomenclature and specifications for various aluminum zirconium polychlorohydrates, which are useful in this invention. . This is all shown in Table A below.

Table A Aluminum Di 2.1 or less - 1,52, 0 or more -6
, 0 Ruconium Bird, Smaller Chlorohydrate Aluminilla A, 1.5 or less - 0,92, 0 or more - 6
,0 zirconiumte or more, less than.

Aluminum trachlorohydrate 2.1 or less - 1,56,0 or more = l
α0 Zirconium PE More dog, below.

Phtachlorohydrate aluminum・1.5 or less -0,96,0 or more -1
0,0 Zirconium O or more, or less.

Phthachlorohydrate A number of aluminum zirconium polychlorohydrate complexes useful in the present invention are commercially available.

Reheis Chemical Com, pany is the general trade name ttEZAL” C+)
recommends a series of substances under the name The following table lists some of these compounds along with their specifications.

Similar products are Wickhen Prodv, cts,
Inc., and Comet Chemical Corp.
Sold by ration.

Other active ingredients suitable for use in the present invention consist of mixtures of avenium chloride and aluminum compounds that are less acidic than aluminum chloride, such as aluminum hydroxychloride (or aluminum chlorhydroxide). These are described in Canadian Patent No. 958,888, issued November 26, 1974. As will be appreciated, this patent discloses an aluminum antiperspirant material consisting of a mixture of powdered aluminum chloride and a water-soluble salt of powdered aluminum (which is less acidic than aluminum chloride). The amount of aluminum chloride and water-soluble aluminum salts that can be included in aluminum antiperspirants can vary to some extent.

However, expressed as a percentage of the total weight of the powdered aluminum antiperspirant material, aluminum chloride generally accounts for 5 Q wt % of the IO and preferably 20 wt % of the IO, with the remainder being more acidic. It consists of aluminum salt with low content. In the case of aluminum chlorhydroxide, it is convenient to express the relative amounts of aluminum chloride and aluminum chlorhydroxide using the molar ratio of aluminum to chloride in the dry mixture. In this case, the molar ratio of aluminum to chloride is about 0.78:1 to 1.
It is in the range of 95:1. Preferably this ratio is 1
．． a8: to 1-79:1.

In the preparation of this antiperspirant powder mix, in addition to aluminum chloride, any other water-soluble (less acidic than aluminum chloride) known to those skilled in the art to be effective as an antiperspirant may be used. It is also possible to use aluminum compounds, illustrative of which are:
Aluminum chlorhydroxide, aluminum sulfate, “rehydrol” (aluminum chlorhydroxy-propylene glycol complex), zinc phenolsulfonate and chlorhydrol (aluminum to zinc ratio 12:l to 6:1) Yuugata, potassium aluminum sulfate, “W
ickenol 868D" (luminium chlorhydroxide-polyethylene glycol complex), etc. However, a preferred aluminum compound with this feature is aluminum chlorohydrate. In a preferred form, it is used as a finely divided powder. .

Still other antiperspirant materials that can be used in the present invention are prepared from aqueous solutions of aluminum chloride, ACH, aluminum-zirconium polychlorohydrate complex, and a buffer such as glycine. These can be spray dried into a fine powder and incorporated into the stick compositions of the present invention.

The amount of antiperspirant contained in the sticks of the invention can vary somewhat. Typically, the antiperspirant will be about 10.0 wt% to about 60.0 wt% of the total weight of the composition.
preferably about 15. Owt Chi to approx. 26
．． Configures 0wt excellent.

It may be preferable in some cases to include a lipophilic agent as an optional agent in the antiperspirant sticks of the present invention. One class of materials of particular interest are propoxylated lower alkyl alcohol ethers. A variety of lipophilic agents can be used for the purposes of this invention. One of the materials available on the market is sold under the trade name FLUID AD. The CTFA designation for this substance is PPG-1
4-butyl ether.

The antiperspirant stick compositions of the present invention can be manufactured using conventional methods well known to those skilled in the art. A typical method is U.S. Pat. No. 4,14 to Ggrsα et al.
1. 'I 50.

The following examples are presented to further illustrate the invention, but it is to be understood that the invention is not limited thereby.

Example 1゜Stearyl alcohol 9.00
Castor wax (MP 80)
4.00FT 800 Waa;
Since 2.0 Ophbid AP
3.00 Jonol CP rice future
0.05 dimethyl isosorbide
47.95 talc
7.00 fragrance
i, o.

100.00 US PPG-14 Butyl Ether (CTFA nomenclature)
Future 2,6-G T-Fyl P-Cresol Method: 1. Weigh the skin softeners dimethylison rubide and Flrbid AP into a suitable stainless steel jacketed pot, tender, and apply a medium lightening mold. Add aluminum zirconium trichlorohydrex-Q11/powder using mixer ρ stirring.

2. Slowly increase the temperature of the mixture to 110° F. with moderate stirring.

3. In a separate stainless steel steam-jacketed kettle, combine FT300 wax, stearyl alcohol, butylated hydroxytoluene, and Masi Wax, Merck. Melt until clear by heating to 210°F.

4. Add the contents of Step 2 at 110°F to Step 8 at 185°F with moderate agitation. A homogeneous homogeneous suspension is obtained. Cool the batch to 125°F.

5. Count at 125°F just before filling containers.

6. Product filling guideline a: Charging@temperature 158-160°)゛b=cooling temperature
The relative staining (smearability) of antiperspirant stick compositions of the present invention on fibers for 15 minutes at 40°F was compared with that of a control stick composition containing volatile silicone in place of dimethyl insorbide. The following compositions were prepared for testing in comparison to:

Code B Stearyl Alcohol 9.00 Castor Wax MPB8 4.00FT
800 wax 2.00Fhbi
d AP 8.001o
nol CP O,05
Silicone 7158 US 47.45
Talc 7.00
REZAL 410 26.
00 Fragrance 4201 AP IFF” 1
．． 00100.00 US Cyclomethicone Mirai Type: Floral Aldehyde Code C Commercially available antiperspirant stick product with approximately the following composition: Ingredients wt Al/Zr Tetrachlorohytrex 22-25 Cyclomethicone 45-50 Flui
d AP 5-10 stearyl alcohol 9-15PEG
(100) Stearate l-2 Talc Yuzuki Fragrance A small amount of each of the above formulations was added to the formulation of Example 1 (Fn 1775-sa) for acrylic, acetate, cotton, nylon,
Used to treat polyester, rayon and wool fibers (cloth). The treated fabrics were then used for strength reduction tests and stain tests. After any of the above formulations performs one treatment, 1
It showed a decrease in tensile strength of 0qb or more. However, the Code A product of the present invention was significantly more efficiently removed from all treated fiber samples than was the case with fibers treated with Code B or Code C formulations.

The stain test method is as follows: Stain Test Near type fiber fabrics (acrylic, acetate, cotton, nylon, polyester, rayon, and wool) were used, cut into 8X1O inch sizes. The product to be tested was applied to each fiber fabric and the fabric was hung in a row to dry at room temperature for a minimum of 16 hours or a maximum of 24 hours. Samples were washed in a Kenmore domestic washing machine. For cotton fiber fabrics, normal conditions were used in hot water with a load of 4 pounds, and for R4 synthetic fibers and wool, delicate conditions were used in hot water with a load of 4 bonds. AATCC detergent was added. The test water was softened to zero hardness.

The samples were hand ironed using the appropriate settings for each fabric.

For dry cleaners, two sets of fabrics are contaminated;
After drying for 24 hours, it was dry cleaned.

Fiber cloth, put it on the black side and Deerin
The degree of contamination was determined by comparison with the gMilliken oil stain set. A sample with no contamination is given a score of 5, and a sample with severe contamination is given a score of 1. Quite often the stains are yellowed or have non-oil residues. I specifically noted this. The contamination test was repeated four more times for a total of five times to determine if there was a cumulative effect.

Practical Performance Criteria: After 5 treatments and washes, there should be no visible stains (stains) on the white textile fabric.

The results of the study were as follows.

The contamination of the product by all three samples was more complete than the force exerted when dry cleaning/cleaning the textile swatches, and the acetate damaged in Sample A is not a popular everyday textile. Cotton, common textiles, especially underwear, were contaminated with deodorant sample C. A rating of 5, no visible contamination (stains) is required to pass the criteria.

Each of the three deodorant samples meet this requirement for dry cleaning, but not for laundering.

Although the invention has been described with reference to specific embodiments thereof, it should be understood that many modifications and improvements can be made without departing from the spirit of the invention.

152

Claims (1)

Claims: L. An antiperspirant stick composition comprising an active antiperspirant substance dispersed in the form of particulates in a waxy substance and also containing a water-soluble emollient. 2 The emollient is added to about 15% of the total weight of the stick composition.
An antiperspirant stick composition according to claim 1, wherein the antiperspirant stick composition is present in a range of % to about 80% by weight. a The emollient is added to about 20% of the total weight of the stick composition.
An antiperspirant stick composition according to claim 1, wherein the antiperspirant stick composition is present in an amount of from about 60% by weight. The antiperspirant stick composition according to claim 1, wherein the water-soluble emollient is dimethyl isosorbide. a The dimethyl insorbide is added to about 3 of the total weight of the composition.
An antiperspirant stick composition according to claim 4, wherein the antiperspirant stick composition is present in the range of 5% to about 60% by weight. G. The antiperspirant stick composition of claim 4, wherein said dimethyl insorbide is present in an amount ranging from about 40% to about 50% by weight of the total weight of the stick composition. 7. The antiperspirant stick composition of claim 6, wherein the waxy material is a low melting point waxy material. a The waxy substance has a temperature of about 1,007°C (37.8°C to about 1°C)
An antiperspirant stick composition according to claim 7 having a melting point in the range of 50'F (65,6°C).a Claim 7 characterized by a high melting wax that is insoluble in water. The composition as described.
, 6°C J to about 215"F (101,7°C). IL. 12. The waxy gelling agent comprises FT-300 wax,
12. The composition of claim 11, wherein the composition is selected from the group consisting of Paraffin Wax 133°/135° F. 1195 White Wax, Victory White Wax, Multiwax 180-M and mixtures thereof. 1a The antiperspirant substance is a complex of an aluminum compound, a zirconium compound, and an amino acid.Claim 7
The antiperspirant stick composition described in Section 1. 14. The antiperspirant stick composition according to claim 13, wherein the antiperspirant substance is All/Zr trichlorohytorex-ctty.