JPS59209535A - Vessel partitioned into two - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a trough 2K divided into three compartments and equipped with a member manually operated from the outside of the container 11J11 to mix the contents of the two compartments. 01 with standard diluents such as standard saline solution, dextrose or water.
5 Concerning additive containers that are part of waste containers.

thus adding a predetermined amount of the drug in powdered/liquid form to the diluent by actuation of the additive transfer member;
The resulting solution can be administered parenterally to a patient.

two) different in a way that it is possible to mix them later
Apparatus for providing separate compartments in a single container for separately containing more than tji components are disclosed in US Pat. No. 2476,923 to N1tardy and US Li.
1lQh♂ [No. 3,290,017 and B t+ r
US IN 44RF No. 3,532,254 to ke et al.
listed in the number. These devices have the disadvantage that they do not provide an effective seal between the two components to be mixed (until mixing). Moreover, the barriers between chambers cannot withstand harsh handling and transportation conditions well enough to quickly lose moisture or transfer moisture to the dry crosslinking material.
(1 is easy to use. 1 used from the standpoint of health and Dutch studies ≠ 1
sterile conditions must be maintained. Although the configuration is simple, one of the parts of the device 6 found in the prior art is
Row 11i makes sterilization difficult unless the entire device is assembled in a completely sterile environment. This manufacturing method is extremely expensive.

・A method for storing (two components) characterized in that a small bottle of ρt n1] is mounted on a fli stand and forms the edge part of the flexible container from the beginning, or is later housed and secured therein. A three-compartment container for transferring drugs from vials to bay containers is not available anywhere in the prior art. Drug and dilution 1↑1 in dk1 combination
1 at all? The prior art also does not provide a mechanism for transporting additive containers within a three-compartment container that provides conditions for multi-stage moisture barrier seals for non-collision isolation. The prior art is directed to frame-shaped members for temporarily sealing one compartment of the inner ear from another compartment in a single-container system. By protecting the 711 mating of the stopper and vial in combination with a cover or stopper removal member and a sleeve, multiple conditions can be established to establish multiple fluid-tight or moisture barrier seals between the two compartments. provide.

Therefore, it is a first advantage of the present invention to provide 4 g of a manually operated two-compartment container (hereinafter abbreviated as "two-compartment container") which is not affected by the above and other drawbacks of the prior art. So, there is no chemical action on the surface, so 1
A second advantage of the present invention is the provision of a 1-ton, very compact, manually operable, three-compartment container. The third aspect of the present invention is to provide a 21-compartment container which provides rapid mixing of the contents of two containers. Other objects and advantages of /IOfRyomei will become apparent as the description progresses.

Mouth weight 4 (4 outside 11114i'- Ill of the shape of the edge part or opening of the container, l wall part nλ outside + * + 1 of the container)
Manual 4 of the present invention, which provides a fixing member for a small rξ bottle with a stopper together with a stopper removal member located at 1i1.
The advantages mentioned above are achieved by the device of 1'7B and the disadvantages of the prior art are eliminated. Inside the small bottle and the container of riJ' flexible valley device? The substance can be mixed into the container by removing the stopper by the nuttuber removal device ((j', by the operation from the outside of the sex bag, the inside of the small bottle is removed from the river) into the container. , fluid communication is provided between the three compartments of the mixing reservoir for the fluid contents of the side compartments.

Preferred Embodiment Turning to a detailed description of one embodiment of the invention, a manually operated three-compartment container 20 is shown generally in FIGS. 1-4. This is Edge 2
1 to 2 bills joined and sealed at 1
It is suitable for use with flexible containers consisting of sheets of flexible material. The valley 22 is formed (11f) in such a way as to provide a tight compartment 25 for the diluent reservoir fluid between opposing sidewalls, such as 29 and 31.
i', 4", - Sealed edge 2 of sexual container 21
1, a mandrel sealing member 16I'i sealing the opening 86 of 1-1, a sleeve 24 having a portion 26 within the compartment of the flexible container and a portion 28 outside the edge 21 of the flexible container 22. It should be appreciated that the flexible container is formed from two opposing sheets of flexible material and that the sleeve 24 is intended to be placed between opposing edges, such as shown at 86.

A small glass iWr is placed in a position that fits tightly into the sleeve: (0 is i;"+1Ill 84 is included, and the shape of the powder bed is changed to 1nu1, but ((g11. Small] When Uj 30 is moved to sleeve 241/average height 11, the emme-like ridge 88 facing inward 1111 becomes a small bottle.
30 is in contact with the curved wall portion 90. The small bottle 30 (is a stopper), and the stopper 32 has a small part 36 fitted inside the neck 58 of the small bottle 300. 8ka・
There is a flared portion 36 extending from the top.

Stopper 3 extending from shoulder 58 of small 1i1j30
Expanded F of 2? There are 36 separations and 6 threads 38 for lf, which engage with internal threads formed in the ring 50 extending from the cover 42. -f: As a result, the cover 42 is moved to the stopper 32
It is twisted together, and the skull 1ijl part 48.
The sleeve 2 is separated by a lance-shaped lip 114.
It also interlocks with 4. Annular lip 441/i, outside of sleeve 241. -1q52 is designed to mesh perfectly with the outwardly directed annular ridge 46 extending from -1q52. Therefore, a first fluid tight seal is provided at 114 of skirt 48.
A shape 5y is formed at the contact surface between 1i +fri and the outer 1111 surface of the sleeve 24. The tight sea L on the second 6 inch body is the flat B of tJ50 extending from the cover 42 for 3.1s minutes 5
A fluid-tight seal formed by the inner wall 54 of the sleeve 24 in contact with the rim of the vial
or 111] between the distal end 62 and the stopper 320 and the contact end of the reduced portion 34 of the stopper 32 extending into the neck 58 of the vial 30 and the end 64 of the vial 30. be done. The annular alignment 66 of the cover is fitted into the recess 68 formed in the stop 32 for ease of manufacture and to prevent distortion.

The outwardly extending portion of the vial 30 can generally be covered by a camp structure, which structure is attached to a flange 80 formed on the (outer) portion 28 of the outer sleeve 24 of the flexible container 22. A sealing flange 72 is included.

Beacon 1. A hanger 75 is integrally formed as part of the cap 70 to facilitate hanging of the three-compartment container, such as when part of the V-system (not shown). Generally, 1
There is a liquid diluent 82 in the flexible container 22.
6:4 or can be used to administer a mixture 83 of fluid 82 and drug 84 held in 3O. The lower 4 can also have a conventional diaphragm 76 and cap 78.

Figures 5-13 represent several aspects, here Figure 1
The same reference numerals as used in FIG. 1 are used to indicate components having a configuration and a 10" capacity, structure and relative arrangement. 5 and 5A show that the vial or inner container is sealed with a seal in the outer container in any embodiment. 41-k is step 1)-step 2
A second embodiment 120 is generally represented by a barb member 188 having both ends of the sleeve 24, the barb member 188 having a pair of arm members connected by flexible portions 194 to both ends of the sleeve 24. 90 and 192. When the barb member 188 is bent outward as shown in FIG. 5, the stopper 32 and cover 42 are in a fluid-tight relationship with respect to the vial 30 and sleeve 24. When extended or bent inward as shown in FIG. Transfer to the powder 82 in the flexible container 22.

6 and 6A generally depict a third embodiment 220 in which the connection of cover 42 to sleeve 24 is a strap 296. FIGS.

Strap 296 has stopper 32 and cover 4L! The combination of: is made into a one-to-one unit with a fluid seal on the back of the hand 43Q and the sleeve 42, respectively. When it is desired to mix the diluent 82, use the switch 32.
The combination of and C-32 from sleeve 24 i! 1
i,! : l ¥11 and the sleeve 24 and small bottle 30.
I'm going to make a tree.

Fig. 7r1: The fourth ridge with the tab member 398 attached to the cover 342 is expressed as 1<'+1. It can be grasped from the outside of the side, and the combination of ) J ノ <-:', 12 and stopper 32 is attached to sleeve
This is done for the convenience of the user when removing each from the ri 30.

Figure 8 shows how to fill the empty container 22 with diluent into the flexible container I'II', remove the cover 42, activate the small IIIL, and later sample the mixture (7IT, V administration set). A fifth embodiment 420 is generally depicted that also includes an entry/exit member 402 that can be used for the insertion of a syringe cannula 404 or spike 406 to connect to the syringe cannula 404 or spike 406.

FIG. 9 generally depicts a sixth embodiment 508 in which a central latch member, generally designated 508, is disposed within a recess 568 in the center of the stopper 532. This corresponds to the screw engagement 38.40 shown in Figures 1.5.6 and 7.
Instead, it is used to secure the cover 542 to the stopper 532. Recess 568 is stopper 53
A lip 511 directed inwardly around its outer edge to engage a protrusion 512 of a latch arm 514 extending from cover 542 into two glue recesses 568.
have. The lower portion 526 of the sleeve 524 in the flexible bag 22 terminates in an outwardly tapered portion 516, which corresponds to the taper of the protrusion 540 of the cover 542. 7 A tapered lug 518 slides down the sleeve 524 and the tapered portion 516 slides down the protrusion 5.
40 can be attacked from outside. In this way cover 542
or is held on sleeve 524. Strap 59
6 covers the flanged tapered ring 518 54
2! , 5 sho 1 ts have filed an appeal. Therefore, the tapered ring 518 that fits the flange and the latch joint work together to hold the cover 542 north of the sleeve 524 and in contact with the stopper 532.
.

Igl ], Oi! A seventh, more general version of 620 using a separate second rotating sliding engagement part 608 to secure the cover 642 not only to the rubber stopper 632 and sleeve 24 but also to the vial 630 Expressed in 112 on the cover 642]: jif+screw engagement 640 and the protruding portion 612 of the second rotatable force/fitting member 608 have a cut length r, 1゛I minute (510 The protruding portion 612 operatively engages an internally threaded portion (514) formed on a minor surface of an annular lip 660 extending outwardly around the mouth or end of the vial 630. Pressure 4 is applied to the stopper 632, and a ring 690 is formed.
Zru. From the annular shoulder 680 of Ka-642, another seal or 11 is formed by the force of the pressure ring 690 along with the small bottle of real sex 662.

FIG. 11 Removing the H cover 742 to secure it not only to the rubber stopper 732 and the sleeve 24 but also to the roof tile 30 using a separate ring bracket (generally designated 708) It generally affects deafness 720. In the case 750 made on the cover 742,
includes an iit screw 740 and an extended launch portion 710.

There is a protrusion 712 on the latch part 710, which is small and small.
if (, 30, the bottom 1ti'l of the Ju-shaped lip 760 extending outward around the mouth of
+ap-f i I). Inner ti of 15F screw 738! if to stopper 7: (2J-) the compression ring 790 is formed. From the nojolder 780 to the end!'':i, the force of the compression ring 790 towards 762 forms a tight seal to another fluid. SafLru.

Figure 12 shows Town i♂1・1 case! A ninth embodiment 820 in which a flange 846 is formed on the IIt'#iB 824 of the sleeve 824 extending into the vessel 22.

As shown in FIG.
5Y1-, but if the sleeve 824 is opened, the flange portion 84:3 of the cover 842 shown at 850 is in contact with the flange 846. A tab member, which is secured by the cover 812, is used to push the cover 812 out of the sleeve 824 during activation of the f41 field.

Figure 13 shows - ('l'J with a closed end small il, denoted by q23, "j," where the containment casing is used.
The aspect 920 of 7-ru in Eno Di 21 of ÷22 is expressed implicitly. Hanging device 975L
'l, small j (1), collection 17' end 9 of k/ink 923
It is attached to 25. The two-car wall part 927 is a housing case/
Welding of bag 22 to ring 923 provides space for a convenient internal mandrel support tube.

114-2514 illustrates another embodiment of the present invention in which separate seed vials, such as 30, are packaged separately from the flammable container 22. Therefore, rather than being sealed by the sleeve 24 through the container wall, the vial is
It will be secured into the mouth 14 by reception and interconnection through the y-body member.

This phase connection may be useful in a hospital pharmacy, for example.

State described (Contest 10.110.210.310.41
0 and 510, the same components are referred to by the same numbers as previously described.

In FIG. 14, an embodiment 10 is shown generally including a vial 11 having a conventional neck 12 with threads 13 extending outward therefrom. Corresponding Neshi 15U16 and town 1. The sounding container 22 is mandrel-sealed and is being heated to the inside 14.゛Husband bought JOj song hit IJ
The gasket 18 rests on the shoulder 31 of the mouth 14, and is located at the end of the small bottle! a51 and 7 = ring 1 - has legs 33 for holding. Gasket 18 is attached to annular flange 17
Recess 19 in gasket 18 to cover self II
Through it, it is fixed to the opening 14. Cover 55 and sometimes L
From the gasket 18 on the tight interlock with the n-shaped wall 67, there is a 15-minute 27 push. The cover 55 has a latch 09 that frictionally engages with the shoulder 73 of the latch portion 69, and the shoulder serves to bring it into contact with the lip 71 of the latch portion 69. Small bottle 11 has a small radius! Dilute +11 with stopper 41 with 'ilj minute 47 and minute 7 middle part 45
It has been sealed in history from the beginning. Each part has a circle 1ii11 of the vial 11, such as a vial neck/I9 and a small; The stopper 41 has a flange 65 and a groove 61. The recess 61 has a 7-inch shape to receive the protrusion 59, and has a lip 63 that engages with the collar/white 5 and a four-segment portion 57 with the cover 55. The cover 55 also has a side wall 95 for internal connection with the FDJ bond wall 67.

15.16 and 17 generally illustrate another embodiment 110 and will be described with respect to FIG. Small+! j, 30 is packaged separately 1101 from the container 22, and a sleeve 124 surrounds the small bottle 3o except for the stopper portion 141. A cover cap 101 seals the sleeve with flange 80. Similarly, cover cap 102 may be located over spout 114 and is in the form of a hanger. 9. Referring to Figure 17, mouth 1
14 has an inwardly extending flange 115 on which a sleeve 1240-like protrusion 146 is located. It should be pointed out that up to this point, the annular projection 146 has probably moved through the cover cap 101. This position of the mouth 114: 6, the sleen flange 80 is the mouth flange 1
Connected with 79;・There will be one insect. A gasket 118 is placed inside the mouth 114, and this gasket has a section 193 located at 1:31 of the mouth 114.

Flange 11 at the mouth 114 and the interlockable stopper
7 extends from the gasket 118. Annular recess 19
1 is small in gasket 118, 1 circle: 30 edge (edge)
I'm going to receive 62, and I'm not going to get 62? He has the hand Wjl of sealing with i1i 51. Small ++i, inside the neck 58 of the vial to seal the contents of 30 to the history from dilution i'1l182 i! A strut horn 141 with an annular ring 39 that would seal Ill is useful.

The lip 185 extending from the stratosono-141 that engages with the endΩ;^151 requires a tight/- ring for other fluids. A flange 65 extending into the compartment or lhis to contact a lip 63 extending from 57 seals the opposite 41i1.,'ll54
The other parts of the cover 55 with the old group 57 are the ones written in connection with the bad saying 10 and ID]-, so there is no need to repeat them.

FIG. 18 will be explained. In this embodiment, the container 22
↑(a〈α1j 82 and the interconnection and sealing (method →) of the flange 84 of the vial 30 is different from embodiments 10 and 110.

In this book form 210, the edge 62 of the small bottle 30 is connected to the gasket 218 using a recess 297, with an I' of 1.
; L, will be sealed in the mouth 214. Gasket 218 may be retained in port 214 by providing recess 298 in gasket 218 that receives recess 201 as well as flange 219 extending from port 214. The stopper 141 is substantially identical to that described above in embodiment 11.0, except that it includes a lip 185 for mating with the lip 62 of the container (vial), and still has the cover 55 and the front part. You can also see from the diagram that it meshes with 57.

Therefore, these identical components and elements are given the same reference numbers.

Embodiment 310 of FIGS. 19, 20, and 21 generally depicts a vial member 30 that, when filled with cross-agent 84, can be heat-sealed directly to mouth structure 314. In this embodiment, a stopper 341 closes off the head 58 and has a section 361 that receives the projection 359 of the connection part 357. Protrusion 3
95 from the stopper 341 to the flange 3.
65 extends, and there is a horizontal wall surface 395 on the stopper 341 that contacts the wall surface of the reciprocal drawing mold. Extending above the lip 62 of the container is an annular body 300 each having a partially mating recess 301 . The container mouth 314 may extend over the combustible container 22 into an overlapping section 302, for example at 323. gasket 3
04 is received in the recess 305 of the mouth 3J4 for the purpose of providing a sufficient seal between the container 22 and the mouth 314. The gasket 304 is, for example, ]7.F.

At the trust, the container 22 is sealed with 324 marks, but the opening 14 is sealed with 4 marks. Cover 342 is generally shown opening compartment 306 with gasket 307 at 31
j ahead to surround 4. The latch part 369 is the opening 3
The lip 371 mating with the shoulder 373 of 14 provides a removable connection mechanism for the cover 342 to L]3]4. Cover: 342 also includes an annular wall 367 terminating in a sump end wall 308 that seals an insert 358 (described in section 1 below).

At the opposite end of the port 314 is a flange 379 extending laterally from the port.

As shown in FIG. 21, the overlap 302 will be sealed at 581 and 73" and surround the mouth 314.

A service tear section 309 is provided for removal of the overlap.

Figures 22A122B and 23-25 are missing! Mr. Le 410
and 510 use the rigid latching collars of 400 and 500 to secure the container [414 and 5] 5 to the container lip or rim 62, respectively.
represents. Aspect 410 will now be described. 410 includes a multi-component collection X&amp;
It can be seen that a ferrule (gold) 403 is placed on top of the ferrule 2, and that the ferrule 418 is held in contact with the i-peg portion 62. Schlau [
...Tube 418 is the last sentence of I part 30, 1ri5
1 and 1 and extend in the F direction to seal against gasket 407 with recess 411 that receives extension 412 of /nilaud tube 418. D4
14 also has a flange 409 that fits into slot 1-408 of gasket 407. tiJ shape λ+jr of cover 55
: A card portion 439 extends from the gasket 407 for a seal that fits in the 67th position. The cover 55 which engages with the stopper 141 at the attached coupling part 57 is identical (in this respect) to that described in connection with Mr. J 10, as indicated by the same reference symbols. The same holds true for the aspect 510 described below.

・Sweet shape 510 represents another member that seals inside the container 515 with a small opening of the container and 30 as the mouth structure. In this particular embodiment, the mouth 51
5 has legs 531 interconnecting with a T-shaped head 517. In this configuration, the slot 509 receiving the head 517:
, 1f: and a gasket 519 having an extension 521 that partially encloses -f4- of the head 517. A sealing ring 539 connects the annular wall 6 of the cover 55
It extends from gasket 519 to engage with 7.

Collar 500 has a recess 501 surrounding flange 579 and abutting the top of lip 62.

23-25 show the latching January 1 thread of collar 500 for collar 500 and vial 30 at :1j. Collar 500 has a recess 501 surrounded by arcuate walls 502 and 503 connected by hinges 504. From one end of collar 500, opening 1
A latch member 506 having a jaw portion 507 for being held by the break wall 322 extends within the cover 513 . (See FIG. 24) Collar 500 with hanger 575 holding and interconnecting vial 30 and container 22 as sometimes shown in FIG.
It's one step lower. Collar 400f'i is similar in construction to Collar 500 and wraps around edge 62 and flange 479 of Collar 410 in the same manner as described for 2510.

The features of Bonmei's manually operated two-section container can be explained more clearly by describing how to use it. I>14 will be done.

Container 20.120.220.320.420.520.
The operations of 620, 720, 820 and 920 will be described first.

The three-compartment container 20 will typically be received by health personnel, as shown in FIG. As shown in FIG. 2, start up of the two-year-old picture container is started. Grasp the camp 70 with your thumb and forefinger and push the cover 42 into the center of the flexible container 22.

Although not essential to the ease of operation of the three-compartment container disclosed herein, the top 7 yorku 23 can be made into an arcuate shape,
Move the vertical seam 21 on the sleeve 240 side inward 1
Shaping the flexible bag 22 in a flexible manner reduces the force required to push the sleeve 24 into the l:TJ' flexible container 22 side compartment. - When the cover 42 is attached to the flexible container 22
31 facing the wall 29.
The cover 42 can be gripped from the outside of the container 22, such as a 290 flexible side plate, by compressing the portion proximate the camp (see Figure IB). To facilitate this operation, the cover 42 is provided with seven langes 43.

With the gap 70, it is possible to operate the combination of the stopper 32 and the stopper 32 from the outside of the flexible container 22, as shown in FIG.
2 can be removed from the vial 30. This is drug 84 taken from small bottle 30 at town 13'51, drug container 22.
Drop into dilution i+182 in section 0 25 (+!!
Fruit 3, cephalothin, oxacillin, nafushi 1 non, fampicillipeticalcillin, carbenicillin, drug 1
drugs such as one of the various pharmaceutical products in powdered or liquid form, such as antibiotics lv, vitamins or nutritional preparations (such as Nothromain, Nitropurunt and Hissuccinylcholine)84
water or a diluent such as dextrose or saline solution82
It is also possible to further manipulate the outer wall of the flexible container 22 to aid in its thorough mixing to form the mixture 83. When mixed, the stopper 32 and the force, as shown in FIG.
<-42 was observed in the combined crab mixture 83, which would indicate that the three-compartment container was activated. The handle 75 holds the three-compartment container 20 at 1. V, used to attach to the hook 77 from the ball.

The embodiments shown in FIGS. 5-9 and 9-13 operate in the same manner as described for FIGS. 1-4, except as noted below. To explain in particular, "When the walls 29 and 31 of the T-burnable container are faced and pressed, the barbed member 188 will be touched." - Glue member 188
inward to create fluid communication between the two drawings. The action of pushing straight on the barb/L member 188 pulls the stopper 32 and cover 30 combination away from the neck of the vial 30, displacing the drug 84 into the diluent 82 as shown in FIG. 5A.

In the embodiment of FIG. 6, the stopper 32 and cover 42 combination does not fall into the mixture 83, but is held against the sleeve 24 by the straps 296.

The embodiment of FIG. 7 uses a tab member 398 to remove the combination of the stopper 32 and the cover 342 from the container, instead of operating the mating 411 of the stopper 32 and the cover 342 through the walls 29 and 31 of the flexible container 22. 4))ζ Same as in Figure 1 except that it is controlled only from one part of the side of 22. 4))ζ
7. In FIG. 8, 1.・Suho 420, 2 Igl
+Iji container is shown in container 22 without dilution. Under these conditions, the diluent can be completely inserted into the lower 4.
I can do it. ￥≠After pouring the diluent into the container 22, raise and assist the two-compartment volume A, ÷, and mix 4"il+ with the diluent. Spike 406B1.V can also be attached to the administration set. Alternatively, 14-2 of 11402 can be added to container 22 in the usual manner.
It is also possible to use P3 instead of rii III 1.

Figure 91. ``14J>Q In 520, 1 moves the flanged tapered ring 518 to the outwardly sloping portion 516 of the sleeve 524 1 &, l without moving to the upper 1 rule. is the tapered part 5
16 and the protrusion 5 holding the cover 542 to the sleeve 524.
40 Reduce the VC or X force. The flanged tapered ring 518 can be ramped upwardly and outwardly 1-11 over the sleeve 524 until the strump 596 is fully extended. The protrusion 512 from the cover 542 is the stopper 5
If the stopper 532 comes off below the ring 511 of 32, it will cause the stopper 532 to fall off the small bottle 530 when a downward force is applied to the cover 542.

Drug 84 thus combines with diluent 82 in container 22.

In the embodiments shown in FIGS. 10 and 11, the extension 61
0 and 710, which are effective for better sealing and do not impair operability.

The embodiment shown in FIG. 12 grips the container 22 through one of its flexible sides, e.g.
Weak bathing suit I'-Peel off, stopper 32
Provides the disadvantages of removing the bottle 30 from the vial 30. Shown in Figure 13! Bank I, -1.020, is operated in exactly the same manner as in FIG.

I will describe the work of Mr. J/Ri shown in 114-25. IJ<, small 11 circles 11 and 30 shown above are i
1. The flexible musket 22 and the pine tree will be separately mulched and packaged in the manner shown in FIG.

In this case, the small Nt11,30 (/:1 cover cap 1
The stopper 141 that was inserted in 01 may be included. The contents of the small bottle 30 are transferred to l'? of the container 22. l r! 4, Camp 10
1 and 102 = Remove the adjacent part of the sleeve 124 D
] 14 to () 1i person's purchase letter] Intermediate it' bow 146 rides Dl, flange 115 of 14! Make it look like 1 no Uero (see Figure 17). At the same time, the small bottle 62 is stopped by the stopper 11.
．． At the same time, the lip 63 of the connecting portion 57 will fit into the recess () and the 7 flange 65 in contact with the annular recess 191 of the cover 55. Since it is sealed against the wall 67, another sealing will be applied to the gasket. If desired, a sealing ring, such as 39, may be provided on the wall 119 to contact the wall 1467. cover 5
5 average (,t V Korikiki Sket 118 has been up to this point, Tani-I!
Ken 22's) i, J in the cover 55 that was inside the 1st use
Placed within 114: The river that has been fixed! ]-4.

Nobui Ei 11 ON, " 2 I)"Nries' 1 "〒Kake 1 S 1 state 6 Q t' 1.) 6 tl note i,
You will wake up in a good manner and get +11. This is accomplished by pushing the vial 30 into the body of the container 22 as shown in FIG.

Small bottle 30 or I? Assuming that the position shown in 12 is at 1f~, the cover 55 is preferably moved by the fourth finger and the third finger.
)1...4 will be assisted by the flange 179. In action 1 of peeling off the vial 30, the latch portion 69 is removed from the shoulder 73. Cause 6, this is an illusion, then,
One movement as the action of pulling the stopper 141 apart, and its chipping.1. +: The DSr portion 52 is transmitted to the protrusion lip 63 by 14 uJ on the upper 2 strokes/white 5''. Continuous pulling operation (thus, stoppers 1 and 11 are attached to small bottle 3)
i'11 away from the neck 58 of
This may cause the person to fall during 182. Therefore, yI': Is the cover 55 with the Kyuto 57 and the J knob 63 removed? It becomes rlJ material.

When the small bottle 30 enters the small bottle 30 or 114, any attempt to separate the small bottle 30 will result in the spillage of the plow powder 84 to remove the stopper 141. Please be assured that the 1♂Higu 110 provides a tough bar indicator system that can be easily tolerated. The I+1x1o also offers pre-assembly flexibility.

Attached to this, the sleeve flange 80 is attached to the mouth flange 179.
It is achieved by sealing.

The interconnection into the mouth 14 of the vial 1 in embodiment 10 is according to embodiment 1.
10 is substantially the same as described above, and the joint points are the sleeve to the mouth and the flange type C↓ at the end of the container.
Instead of mating, it is the thread action provided by mutually threaded screws 13 and 15. The action of the screw continues until the end 51 of the small 19 stops on the gasket 18.
1-<, The stopper 41 is removed from the opening 14, and as a result, the stopper 41 is removed from the opening 14. 1. It can be removed in the manner described above in connection with O.

! j, Mr. H4 210 The feature of the operation is the method of securing it to the inside of the mouth 214 of the small bottle 3o. As shown in the figure, the edge 62 of the tile is attached to the gasket 218
When the vial 30 is properly seated in the recess 297 of the retainer 214 together with the attached stopper 141, the retainer 30 is properly seated.
A plug 270 will be positioned on the end of the container 30 to secure it. It should be noted that the retainer plug 270 has a shoulder portion 200 that engages the flange 280, and that the shoulder is formed in a manner similar to the actual length 287. The retainer plug is also prevented from engaging the port 214 by an undercut 273 that engages the L'214. If using a short vial, use a larger,
A deeper plug 271 can be used, so plug 2
71 in the mouth 214. Similar to the previously described embodiment, for fixation to the vial 300-neck 214, the coupling part 57 with lip 63 would engage the flange 65 of the cassette 141.

At this time, the activation of the ritual device system (d would be similar to that shown in conditions 110 and 10 above).

1M>, 'A 310, the container 30 is entirely connected to the mouth 31.
It differs from the previous one in that it is connected to 4 and this is done at the time of manufacture. This d: Hot
This may be done using a plate or hub 303, and as shown in FIG. 19, 303 is j;i'! 300 and the flange 379 as well as the last layer 308 and the insert 358.
When the river is heated, the heat l′lI′uj property (
(t1 fat) 101 will then stick them together to form a container system as shown in FIG. This heating method provides the advantage of creating an abutting surface of the 7-lunge 379 to the butterfly 300 and the end of the 1-wall 308 to the insert 358. To activate this Neph organ system,
By removing the lip 371 from the mouth 3] and 4, the cover 342 is freed from the mouth 314, and as a result of the pulling action and the stopper 341 being removed, the end wall 3 is removed.
08 and 41+7. ! i-395 is integrated into the connecting part 3
57 will be formed.

The operations of embodiments 40 and 510 are performed using the latching collar 400.
It is different from the previous one in that it uses o:5oo. Latching φ Kashi-400 and 50 (N, (/) law,
) 1-1-62 is fitted into the Niraud tube 418 and gasket 1-519, respectively, and the small fH is fitted.
j: 30 'K to 1 when done, valley''); 3
0 respectively D 4.1.4 and 515 and i outside: l light and 1 will be done. Figures 22A, 22B and 25
Color 400 and 500 (C'K,
Recessed V(hi”;:ls 3-shaped wall 4,0 like 501
2 and 502! I! A shows 4 LO d, ), Z
yb −/L, 4 Q 3 with 9'/7' 62 and 1% fQ insect,! f only 4;k 510 tel/:K
') ツ7''62 VC Direct] 夛jQ Insect Beetle will catch Fran Ji 479 and 579 respectively.

After latching with collars 400 and 500, respectively, activation of any of these H threads 41.0 and 510 is as follows: iy of cover 55, as previously described.
, '4 and connection, 157 VC stopper 1
There are various methods for manufacturing a compartment container in Z with 1・l$<pulling action on 41 and in 4i4 standing, but 1
) 111 It is best to start by forming a container from the two notebooks of the Tsukasa and Ito material to form the walls 29 and 31. The sleeve 24 has 1"14.114.
414 and 515, 6 units above 1'1b] 8
6 holes are provided, and ``lower 4 nozzle opening'' is provided at the low end of je+-. The cover 42, 55, 342, sleeve 24 and [] are assembled with sterile strips and the edges of the dimension 22 are RF mandrel sealed or heat sealed. In the same manner, the lower part 4 is also RF sealed or heat sealed to the tube 22. As a result, the sterilizing container 22 can be filled with the persimmon agent 82 through the lower 4 in an aseptic manner. After filling, cover the lower 4 with the "H" type dosing [76] and the gap 78. The vial 30 is filled with medicine; rinse it with DL 84, drain it, and seal it with a stopper 32 without spilling. In the embodiment shown in FIGS. 1-13, the assembled, filled and stoppered vial 30 is placed in the sleeve 24 under bacterial conditions, and the stopper 32 and cover 42 are removed. Use I engage in miniaturization. The cap 70 can now be attached to the sleeve 24 by welding the RF flange/L7 or heat hose 7 lang 80 to the flange 72. Figure 14
-22 In the case of the convergence shown in B, r soil, small bottle 30 or 11
1 will be covered with a closure cap like 101 after filling and stoppering, and the valley-shaped mouth will also be 114.
1, as shown in Figure 13, provides another means of production. Instead of inserting the vial 30 from the sleeve 240m rq+ of other embodiment C, the vial storage casing 923 is seal-lipped into the edge 21 of the flexible container 22, and [)II is filled with it, sterilized, and capped. A small bottle covered with
The container can be inserted into the small bottle cage/gage 923. zJ□]II (Pick 30 and insert it into the L-shaped container 22 and into the small bottle storage casing 1)
II. Place the cover 42 on the stopper 22. Lip 44 of cover 42-F in a manner similar to that shown in FIG.
The vial is held in place by a snap fit onto the ridge 946 of the vial receiving casing 923.

1: To +i' 10.110.210.310.410
and 510, the interconnection between the vial containers 11 and 30 and the flexible container 22 is such that the coupling member of the container opening provided in the flexible container opening and the container vial 11 and 30 are connected to each other by 1.11τ.
It should be understood that this is effected by complementary interlocking members that are present. The engaging members provided in the '8 mouth are the screw 15 of the pattern 10, the flange 115 of the pattern 110, the recess 297 of the gasket 218 of the pattern 210, the flange 379 of Qi[310, the gasket 407 of the j2 pattern 410, and Aspect 5
10 gasket 519 is replaced &a. The corresponding complementary interlocking members of the vial containers 11 and 30 are: (4410 screw 13, aspect 110 L7JJ 7 flange 146, aspect: (!% of 10 300, 44>N41
Shroud tube 418 of 0 and small 1 of aspect 510
111, represented by the edge 62 of J.

Town j'4', 1. genitalia cap 70, sleeve 24,
The preferred material for manufacturing the ``1'' and 1'' is a translucent polynisdel or polypropylene plastic material. However, other resin materials such as polyvinyl or polyethylene may also be used. cover 4
2. Ji-t'i for 55 and 342/1
13iiJ: Polyethylene; however, polyester or polypropylene may also be used. :32.41.
141.3 /l 1) stopper line 218
．． Gaskets like 118.218.418.519 are made from rubber, but thermal QR: +i<l+(?l I
f! 111 plastics such as 'r may also be used.

The vials 11 and 30 are preferably made of glass, but it is also possible to substitute glass with a hard or semi-rigid material such as polypropylene or polycarbonate. Although compartmented containers have been described as preferred for powdered drugs in vials and liquids in bags, it is clear that they will work well with any fluids. Please note that this two-compartment container system can also be applied to other packaging applications.
For example, when it is necessary to keep two substances under different conditions (separated) until they are mixed or used, or when one substance that is affected by the surrounding conditions is to be stored, etc. Demerou has a degree of use regarding fluid substances.

As used herein, "fluid" or "fluid content" refers to any drug or diluent that may flow from one container to another as a liquid, solid, or gas. Please understand that it means substance.

It is clear that the present invention now provides a manually operable two-compartment container that is easy to manufacture and use.

The container system of the present invention provides a focal environment for the storage limb as well as for the extended type of fluid material during the mixing period;
Moreover, a cheap system is provided. The (i, :< composition of the vi'-specific sealing (equipment) provides an adequate moisture barrier and substantially eliminates the propagation of one substance to another until vigorous mixing is desired.

The invention described by MiJ has now been put into practice by those skilled in the art. Those skilled in the art are well aware that the present invention is not limited to the particular black color shown here. The scope of the invention is illustrated by the detailed description of the invention set forth in AiJ, and is defined by the text of the claims.

[Brief explanation of the drawing]

Figure 1 is a front view of a three-compartment container that also shows a 1m view of the vertical section. FIG. 1A is a plan view of the three-compartment container of FIG. 1. FIG. 113 is a horizontal sectional view taken along line B-H in FIG. 2.3 and 4 are front views similar to FIG. 1 illustrating the operation of the three compartment container shown in FIG. 1; 1 is a front view similar to that in FIG. 1, and FIG. 5A is a partial view of FIG. 5 showing a second cross-section in which a toggle member is provided between the sleeve and the cover for raising the cover. 6 and 6A are partial views similar to FIG. 5A, showing a third embodiment in which a strap member is provided between the sleeve and the cover. FIG. 7 is a front view similar to FIG. 1 showing a fourth view, but with a tab member associated with the cover; FIG. 8 is a front view of a three-compartment container similar to that shown in FIG. 1 with an additional outlet member adapted for use with a syringe or transfer spike. Figure 9 is a partial view of a three-compartment container similar to Figure 1 showing a sixth embodiment, with a handle member and a tapered strap associated with the cover for activation of the vial; 1 IOi; I, the same figure as FIG. 9 in which an additional sealing member is provided between the cover and the small 1i1j. 1st own 1 is 21.7. Figure 10 shows another example of sealing 'r:rll material between the cover and the vial for the inner container.
A similar partial view. FIG. 12 is a front view similar to FIG. 1 of the ninth embodiment, showing the flange collapse for attaching the cover to the sleeve; Figure 13 is the same front view as Figure 12 of the disciple embodiment of the three-compartment container with additional caps for sealing at the mouth 1'''G11h valley?:8. Figure 14 shows another embodiment of the invention in which the small drawer 1 of the actual i'tl+ is screwed into the flexible container.
Partial side view and partial vertical sectional view. Figures 15 and 16 include r (before securing the small bottle to the container → HJ%) 11111
No figure. (・×1117iJ: A partial side view and partial vertical cross-sectional view similar to FIG. 14 detailing the container system of FIGS. 15 and 16. FIG. A partial side ff+i view and a partial sectional view similar to FIG. 14 representing a vial. FIGS. 19 and 20 are a similar portion to FIG. Fig. 21 is a side view showing the three-compartment container shown in Fig. 20 when wrapped in an overlap bag. Females 122A and 22B are small bottles and containers containing four drugs. Figure 23 relates to the container system shown in Figures 22A and 22B. Fig. 24 is a plan view of the latching collar shown in Fig. 23 when the latching collar is closed. Figure 25 is a 1115-minute side view and (
)・Partial vertical sectional view. Out If! [1 person Abbott Laboratories]
Konto Patent Attorney Ryoji Kawase
7. ``Yo'' (Ij person, patent attorney Takehiko Saito,
-・ Shima FIG, IA FIG iB FIG, 8 FIG, 9 FIG, lo FIG, // FIG, /4 FIG 15 FIG, /6F
IG /7 FIG /8 FIG, 19 FIG, 2
0FIG, 2/FIG, 24 FIG, 25 Procedural amendment ■ (method) % formula % 1 Indication of the law Patent application No. 35443 of 1982 2 Name of the invention 3 Container divided into two parts 3 A beach that corrects the vehicle Relationship with Bit 'p(, fr(J: 6 name Abbott Laboratories, /''':, name patent attorney (6323) δ Aiji... 5 111 fingers 7. e-mail. 8 attached
゛ 'IIt' May 29, 1159

Claims (1)

[Claims] 1. A first flexible bone container having a flexible wall member having at least one opening; configured to penetrate and secure the wall member of the second container. , a second container having a removable stopper; a stopper having a portion operably located within the tTJ porous container wall member and engaging the removable stopper; a removal member, and the stopper is configured and arranged to be removable by operation of the stopper removal member from outside the flexible wall member, so that the wall of the flexible container a removable barrier separating the inner containers, characterized in that the stopper of the other container is removed from the other container by external manipulation from outside the body member, and the fluid contents of the inner containers are mixed CUm; A device that stores the fluid contents of two containers separately and then mixes the fluid contents of the inner container. 2. The device according to claim 1, wherein the second container includes a wall member having an edge portion, and the second container is disposed approximately 1 ml through the edge portion. 3. The flexible container includes a wall member having an edge portion, a container receiving member for the second container disposed through the edge portion, and the second container is the second container receiving member. 2. The device of claim 1, having complementary receiving members that interlock. 4. The second container includes an eye structure component having a stopper removal member disposed thereon! +￥♂F The device according to claim 3 ((L 5 A flexible outer container having an edge, opposing side walls and at least one mouth; disposed through the edge of the flexible container) sleeve;
a vial with a stopper positioned in the flexible container at the end of the sleeve and the vial; Constructed to be removable,
The arrangement is complete, and it is nJ"+AS'fi:'
t111 A section characterized in that the stopper is removed from the vial by external operation from the wall, allowing mixing of the fluid contents of the vial and the flexible container; A container divided into three compartments. 6. Cough sleeve hangs ~ works as a member! Time,,'!
'f A container partitioned into three compartments according to claim 5. 7 edge,] 7 inches (11', secondary and at least
An initially empty first removable outer container having a mouth of 1161 mm, with a container stopper of 1 to 32 lbs. a second tube with a stopper fixedly disposed through the edge of the container, the stopper being fixedly disposed through the edge of the container, the stopper being fixedly disposed through the edge of the container;
constructed and arranged so as to be removable by operation from the outside of the wall, and a fluid substance can be introduced into the flexible container from the vaginal opening, and the side wall of the flexible container Alternatively, the fluid contents of the three compartments can be separated by a removable barrier, characterized in that the stopper can be removed from the second container by external operation from both side walls and the contents of the secondary container can be mixed. A device that mixes both the two streams in one of the six then 1 TOj. 8 Initially filled with said () (14 cannulae or spikes, then tV, constructed and arranged to accommodate the cannulae or spikes of the administration set +y, I of the tr claim)
fj'l Section 7 Section 7 Enclosure 9, at least 21141
a first container having a removable stopper and a light-sensitive wall member; a container engagement member and a stopper engagement member are provided, and the second container includes a complementary engagement member interconnecting the two container engagement members, and the second container engagement member TF+S is connected to the container at the vaginal opening. When engaged with the interlocking portion and interconnecting the stopper interlocking member with the removable stopper, an external view of the stopper interlocking member from the outside of the flexible wall 59 The work is effective in removing the stopper from the second container! jJ, the fluid in at least two containers separated by a removable stopper, allowing mixing of the first and second fluids of said container in said second container; 10 The container interlock and complementary interlock: is
The material is provided with a female thread extending from the vaginal opening and a male thread extending from the neck of the second container, and the stopper engaging member is provided with a recess of the stopper and a connecting portion that engages with the recess. The device according to scope item 9. 11. The container engaging and complementary engaging members are provided with a sleeve member having a raised member extending from the sleeve and a 7 lange extending from the vaginal opening that engages therewith, and the stopper engaging member is provided with a recess of the stopper and a flange extending from the vaginal opening. 12. The device according to paragraph 9 for use in the small morning of the claim, provided with a recess u1 (which engages with the recess). 12. a gasket member having a recess that engages with the annular b1 (material and the annular body) extending from the second container to the second container; A load r in which the member is provided with a contact and reading section that engages with the recess of the negative IJ and the recess of the shadow IJ [device according to claim 9 hd &. A flange member extending from the vaginal opening to the outside IH:1, an annular member extending laterally from the Dm double container finger J, and a collar member that engages with the flange member and the annular member; First, the stopper engaging member is provided with a recess of the stopper and a connecting portion that engages with the recess.
a lip member extending laterally from the neck of the second container to the second container mating and complementary mating member;
an annular member having a recess for accommodating a portion of the stopper, a flange member extending from the core for connection to the annular member;
1,'<Ll-! with a recess in the stopper and a connecting portion that engages with the recess! 1'5'I-, Reason for Emotion 1) The device described in item 9 of the 4th set. 15. An annular member made of a thermal material 1f-1 disposed on the second container engaging and complementary engaging members, at the edge of the second container and window, and at least a portion of the edge;
The stopper engaging member has a portion in which the -i'rB is disposed, and is provided with a heat transferable eye structure formed of a thermoplastic material; 16. The apparatus of claim 9, wherein the portions are respectively fitted to the second container and the stopper-engaging member is fitted to the removable stopper. 16. The device further comprises: The ferrule secures M to the annular member of the second container.
10. The apparatus of claim 9, further comprising a tubular circumferential member having a circumferential ring and a gasket member fastened 1.1 to the CI which engages the circumferential circumferential member. 17. Addition of a reservoir for storing sterile fluid and mixing with the fluid contents of a flexible container having an eye structure with an additive container engagement member and a stopper engagement member, connected with said stopper engagement member by a proboscis container. a container having a removable stopper with a removable stopper, the container including a complementary engagement member that is complementary to the additive container engagement member; :complementary of ÷11<
] When the interlocking member is interconnected with the additive container interlocking member of the flexible container and the stopper interlocking member of the flexible container is engaged with the container stopper, the outer 1 (1 The stopper is removed from the container by operation from the outer flange 11 of the stopper engaging member, and the fluid contents of the container are waited until it is possible to mix the fluid contents of the container in the operation container. additive container.