JPS59176206A - Sodium hydrogen carbonate-containing dentifrice - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

DETAILED DESCRIPTION OF THE INVENTION This invention relates to a toothpaste containing sodium bicarbonate. More specifically, the hydrogen carbonate containing sodium bicarbonate particles have a median size within a specified range (a size representing a central tendency).

A number of different toothpaste compositions are known for hardening, whitening and maintaining teeth. Many of these toothpaste compositions are known for their buoyancy and prevention of stain transfer to the flesh. Contains large amounts of water-insoluble abrasives such as dicalcium phosphate to help with It is widely accepted that in order to preserve teeth for as long as possible, the minimum number of abrasive substances necessary to remove moss and stains should be used in the polishing composition.
It recognized.

Bicarbonate (1) Lamb particles are relatively soft compared to the abrasive materials most commonly used in monolayer compositions. The American Dental Association states, ``If a small amount of 1Tl
Sodium bicarbonate is usually sufficient if needed to protect the teeth from ('a's only staining force).
eutics, ) pp. 340-341 (38th edition,
(1979). Wire toothpaste formulations containing sodium bicarbonate particles as tooth cleansers have been previously disclosed. Reference is made, for example, to U.S. Pat. are doing. l>i9 The size (particle size) of the sodium bicarbonate particles in the kneading polishing compositions shown varies, but most particles have a diameter of between 0.01 and 0.4.
It is preferable that HM is 1 or less. U.S. Patent No. 2,12
No. 8,917 (Crocker) also discloses a green toothpaste containing sodium bicarbonate. This patent discloses that the kneaded box polish contains nearly 50% sodium bicarbonate by weight, and that the sodium bicarbonate particles are sieved by passing through a #200 mesh surface.

Most combined dentifrices today are in paste, gel or powder form. Toothpastes and gels generally contain, in addition to abrasive substances, humectants, water, thickeners, surfactants, flavoring agents, and sweetening agents. Toothpastes generally only contain abrasives, flavoring agents, sweetening agents and sometimes surfactants. Both types of products sometimes contain additional ingredients, for example fluoride additives or colorants, for special purposes or aesthetic reasons.

Kurinanshiki and gels are more convenient to use and are therefore more popular with consumers than powders. However, powder formulations have advantages over toothpaste. For example, humectants, thickeners, and water serve no actual tooth cleaning purpose, but are necessary to provide stability to the desired pasty and gel-like forms. Powders do not require such ingredients.

One drawback of pastes and gels is the cost of non-alcoholic ingredients. Pastes and gels are usually 20-50
% of humectants and thickeners, which contributes a disproportionate share (3%) of the cost of the finished toothpaste or gel.
0 to 50%). Toothpaste is 99%
It can contain up to 100% of useful abrasive materials, thereby eliminating the need for costly (non-detergent) humectant and thickener ingredients.

Yet another disadvantage of pastes and gels is that it is difficult to ensure that these products are stable with adequate quality precision and that their components are miscible. Toothpaste, in comparison, is very simple to formulate.

In the case of pastes or gels containing Soluium bicarbonate as the abrasive material, formulation stability is often a problem. Sodium bicarbonate is unstable in aqueous solution and releases carbon dioxide gas (see, for example, U.S. Pat. No. 3,94
3,240, column 1, lines 32-34). Sodium bicarbonate is also not always compatible (miscible) with other abrasive materials in pastes and gels (e.g., U.S. Pat. No. 3,943,240, column 2, nos. 58-62).
(see line).

In contrast, sodium bicarbonate is stable as a dry powder and is miscible with most other dry ingredients in almost any proportion. Sodium bicarbonate-containing toothpastes therefore have a distinct advantage over sodium bicarbonate-containing linear polishes or gels.

It should be mentioned that, in addition to the above-mentioned advantages, toothpastes containing sodium bicarbonate can be formulated with very high proportions of sodium bicarbonate compared to the proportions possible in pastes or gels. Sodium bicarbonate gives a clean and fresh feel to the mouth. Sodium bicarbonate also helps deodorize the oral cavity by neutralizing unpleasant odors. Therefore, it is desirable to maximize the content of sodium bicarbonate in toothpaste.

However, it is difficult, if not impossible, to have more than about 60% sodium bicarbonate in a paste or gel and keep the product in a usable form due to stability issues. However, toothpaste can contain high levels of sodium bicarbonate.

Therefore, it is desirable that the dentifrice be provided in the form of a toothpaste consisting mostly of sodium bicarbonate particles. Several toothpastes containing sodium bicarbonate particles have been described above. U.S. Patent No. 1,082,
No. 681 (Buna) discloses a sodium bicarbonate-containing toothpaste having a fineness of about #30 mesh. U.S. Patent No. 2,024,146 (Closer)
discloses a toothpaste comprising up to 50% by weight of sodium bicarbonate. The toothpaste passes through a #40 mesh sieve. U.S. Pat. No. 4,276.287 (Covered, Jr.) discloses a periodontal ligament powder (periodontal powder) comprising up to 50% by weight of sodium bicarbonate.
lpowder) is disclosed. The fineness of the hydrogen carbonate particles in this patent is not disclosed. However, these patents do not disclose sodium bicarbonate-containing toothpastes within the scope of this invention. Additionally, the multipurpose baking soda that is commercially available and often has suggestions on its packaging for use as a tooth cleanser contains sodium bicarbonate particles having a median particle size in the range of 44 to 73 microns.

Most of the weight is abrasive particles (including sodium bicarbonate)
One major problem that arises in the formulation of toothpastes is reducing the abrasiveness of the toothpaste to an acceptable level. Excessive abrasiveness leads to loss of enamel and erosion of exposed dentin. Abrasiveness is a particular problem in toothpastes because the concentration of abrasives is even higher than in pastes or gels. Ingredients in the paste or gel also often help adjust the abrasiveness of the overall formulation.

Another major problem that arises in formulating toothpastes containing sodium bicarbonate particles is the salty taste of sodium bicarbonate. It has been found that if coarse-grained sodium bicarbonate is used in toothpaste, the salty taste is reduced and can be easily masked. In order to produce a polishing agent containing sodium bicarbonate that does not have a very salty taste, the use of large sodium bicarbonate particles is suggested. However, with increasing particle size, abrasiveness increases (Wiley-I
2nd edition, 1972
year]; Tinter.

M. L., and S. Nibstein, 30 ('I
'ainter.

M-L, and S, Epstein, 30
) J, Am, Dent, As5oc-No. 103
6-1045 (1943)). It is therefore expected that a high degree of sodium bicarbonate present as an abrasive component in a toothpaste, as well as a significant increase in its median particle size, would increase abrasiveness.

Unexpectedly, it was found here that the abrasiveness of sodium bicarbonate particles decreases with increasing particle size, which can be formulated into a toothpaste consisting of a majority of the weight by sodium bicarbonate particles. Ta. According to various aspects of the invention, sodium bicarbonate is effective in preventing the deposition of flakes and stains on teeth, but does not have harmful abrasive properties that attack tooth enamel, cementum, or dentin. The formulation of containing toothpastes is just possible. Furthermore, the sodium bicarbonate particles are large enough that the toothpaste does not have an extremely salty taste, leaving a new taste in the user's mouth.

In accordance with the present invention, a toothpaste can be produced comprising at least about 50% by weight sodium bicarbonate particles having a median particle size ranging from about 74 to about 210 microns. (
The term "median" particle size in this specification refers to "average"
It has the same meaning as particle size. ) The preferred average particle size of sodium bicarbonate particles in toothpaste is about 7
Within the range of 4 to about 149 microns. It has been surprisingly discovered that such toothpastes are less abrasive than toothpastes in which the average particle size of the sodium bicarbonate particles is 74 microns or less. Furthermore, the sodium bicarbonate particles in the toothpaste according to the invention are sufficiently large so that the bacterial powder does not have an excessively salty taste.

The toothpaste of this invention comprises at least 50% by weight of sodium bicarbonate within the specified range.

The mountain polishing powder preferably comprises from about 75 tons to about 98 tons of sodium bicarbonate. The toothpaste most preferably consists of about 90% to about 98% by weight sodium bicarbonate.

As mentioned above, toothpastes may contain other ingredients in addition to sodium bicarbonate. The toothpaste may contain from about 0% to about 50% by weight of additional abrasive materials. It is desirable for the toothpaste to be less abrasive, so the added abrasive substance has an RDA (Radioactive Dent Abrasive Test) of about 20 to about 100.
(in abrasion tests) values. Suitable abrasive materials for this invention are known and well known, such as dicalcium phosphate,
White materials include silica, alumina, zirconium silicate, etc. or mixtures thereof.

Also, as mentioned above, the dry ingredient of the toothpaste, sodium bicarbonate, is compatible (miscible) with these additional ωfm@'Rs.

The toothpaste of this invention may also contain suitable flavoring agents.

Examples of suitable flavoring agents include, for example, spearmint, peppermint, wintergreen, saf ras, clove,
Salvia (Sage), Eucalyptus (Fiucalypt)
us), Majorana (Mnrjoram), cinnamon (C
innamon), flavored oils such as lemon and orange oils, as well as sodium methylsalicylate. Flavoring agents can be present in the range of about 0% to about 2% by weight of the toothpaste.

A flavoring carrier can also optionally be present in the toothpaste. Such carriers are well known to those skilled in the art. Suitably, the carrier is present in the range of about 0% to about 5% by weight of the toothpaste.

Sweeteners can also optionally be present in the toothpaste. Examples of suitable sweeteners include lactose, maltose, sorbitol, aspartum
ie) and saccharin. Suitably, the amount of sweetener present in the toothpaste ranges from about 0% to about 3% by weight. The flavoring and sweetening agents help mask the salty taste of sodium bicarbonate.

Anti-caking agents such as silica or tricalcium phosphate
It can be included in this toothpaste. Suitable amounts of anti-caking agents range from about 0 ton percent to about 2 percent by weight of the toothpaste.

Organic surfactants can also be incorporated into the toothpaste.

The surfactant promotes tooth cleaning and also improves the foaming properties of the toothpaste. Suitable surfactants are those known in the art, such as water-soluble salts of higher alkaline sulfates, such as sodium lauryl sulfate, water-soluble sulfonated monoglycerides of fatty acids, such as sodium coconut monoglyceride sulfonate. Salts, salts of amides of lower aliphatic amino acids and higher fatty acids, such as sodium lauryl sarcosine, and the like.

The surfactant can be present in the toothpaste in an amount ranging from about 0% to about 2% by weight.

The toothpaste of this invention can further contain fluoride additives to help prevent dental caries. Many fluoride additives suitable for use in dentifrice compositions are known. Among others, sodium, potassium, ammonium, lithium and fluorides of amines, sodium,
Included are monofluorophosphates such as potassium, ammonium and lithium MFP (monofluorophosphate) and other fluoride additives well known in the art. The fluoride additive is approximately O% of the market weight of toothpaste.
An effective and non-toxic amount is present, such as within the range of ~2x M%. The toothpaste of the present invention preferably comprises from about 0 tonne % to about 0.5 tonne % sodium fluoride or from about 0 tonne % to about 1 tonne % sodium MFP (monofluorophosphate) as a suitable fluoride additive. Contains.

A preferred form of the toothpaste of this invention is about 74 to
From about 75% to about 98% by weight, most preferably from about 90% to about 98% by weight of sodium bicarbonate particles having a median particle size in the range of about 149 microns and about 0.5% by weight, most preferably from about 90% to about 98% by weight.
Contains 22% by weight of sodium fluoride.

The following examples clearly illustrate the particles of this invention.

Examples Test Example 1 A test was conducted to clarify the effect of sodium bicarbonate particle concentration on the abrasiveness of a dentifrice composition. Versatile 4 in different amounts in Examples 1.2 and 3 shown below.
Sodium bicarbonate with a median particle size in the range of 4-73 microns was mixed with 504 water containing 0.5% carboxymethylcellulose (CMa) as a thickener. With these mixtures, the well-known radioactive dentin abrasion test (RDA) and radioactive enamel abrasion test (R
EA) (radioactive enamel ab
ration) test was conducted. The results are shown in Table 1. Table 1 also shows the comparative results of the DA and EA tests performed on two commercially available toothpastes that do not contain sodium bicarbonate. Paste A (Crest with Fluoristat)
hfluoristat) contains hydrated silica as a tooth abrasive. Paste B (Colgate dental cream = Oo-Igate dental c
ream) contains dicalcium phosphate as a tooth abrasive.

Table 1 As expected, the results in Table 1 show that the polishability increases as the concentration of sodium bicarbonate particles increases.

Test %12 The preferred toothpaste is 97.32% where the median size of the sodium bicarbonate particles ranges from 74 to 149 microns.
of sodium bicarbonate particles, 2% flavoring and saccharin, 0.22% sodium fluoride and slightly increased other ingredients. The toothpaste contains 0.5% CMC
It was mixed with 59 ml of water, and as in Test Example 1, abrasiveness tests were conducted using DA and REA at different temperatures of 0 degrees. The results are shown in Table 2.

Table 2 These results are 44-7 when compared with the results in Table 1.
The results reveal that bicarbonate particles with a median particle size in the range of 74-149 microns are less abrasive than sodium bicarbonate particles with a median particle size in the range of 4 microns.

Test Example 3 An R, DA test was conducted on the abrasiveness of different sizes of sodium bicarbonate as compared to calcium pyrophosphate. The results are shown in Table 3.

Table 3 As a result, hydrogen carbonate is more effective than calcium pyrophosphate)
IJum shows very low abrasiveness.

The results also show that as the median particle size increases, the abrasiveness of the bicarbonate particles decreases. Therefore, a less abrasive and less salty toothpaste can be formulated with a median size within a certain range and with sodium bicarbonate making up the majority by weight.

Although this invention has been described with reference to particular embodiments, this is for illustrative purposes only and is not intended to limit the spirit or scope of the invention.

Claims (1)

[Scope of Claims] 1. A dentifrice composition comprising at least about 50% by weight of sodium bicarbonate particles as a dentifrice material,
A dentifrice composition, wherein the sodium bicarbonate particles have a median particle size within the range of 74-210 microns and are in the form of a toothpaste. 2. The median particle size of the sodium bicarbonate particles is 74
A dentifrice composition according to claim 1, wherein the dentifrice composition is within the range of 149 microns. 3. A claim further comprising additional ingredients selected from the group consisting of a second tooth polishing material, a fluoride additive, a flavoring agent, a carrier, a sweetener, a surfactant, an anti-caking agent, and mixtures thereof. The toothpaste composition according to item 2. 4. The second tooth polishing substance has a DA in the range of 20 to 100.
(Radioactive dentin polishing test) value. 4. The dentifrice composition according to claim 3, wherein the 5,7-fluoride additive is sodium fluoride or sodium MFP (monofluorophosphate). 6. The toothpaste composition according to claim 3, wherein the sweetener is aspartim or saccharin. 7. Sodium bicarbonate particles as tooth polishing material, 7.
A dentifrice composition comprising from 5% to 98% by weight, wherein the sodium bicarbonate particles have a median particle size within the range of 74 to 149 microns and from 0% to 2% by weight of a fluoride additive. The toothpaste composition according to claim 3, which is in the form of a toothpaste. 8. The toothpaste composition according to claim 7, wherein the sodium bicarbonate comprises 90 to 98% by weight of the toothpaste. 9.7 The dentifrice composition of claim 8, wherein the fluoride additive comprises about 0.22 Ijt% sodium fluoride. 10. The dentifrice composition of claim 9, further comprising about 2% by weight of a flavoring agent, a flavoring agent, or a mixture thereof. 11, at least about 50 IK as a tooth polishing material having a median particle size within the range of 74 to 210 microns 61
A method for cleaning teeth and gums using a toothpaste consisting of % hydrogen carbonate particles. 12. The method of claim 11, wherein the median particle size of the IJium particles is within the range of 74 to 149 microns. 13.42 Additional ingredients selected from the group consisting of abrasive materials, fluoride additives, surfactants, sweeteners, flavoring agents, carriers, anti-caking agents and mixtures thereof; The method according to item 11. 14. The method of claim 13, wherein the second polishing material has an RDA (radioactive dentin abrasion calibrated) value in the range of 20-100. 15. The method according to claim 13, wherein the fluoride additive is sodium fluoride or sodium MFP (monofluorophosphate). 16. The method according to claim 13, wherein the sweetener is saccharin or aspartame. 17, from 75% to 98% by weight of bicarbonate as a tooth polishing material with a median particle size in the range of 74 to 149 microns) from IJium particles and from 0% to 2% by weight of a fluoride additive. 14. The method according to claim 13, using a toothpaste consisting of: 18. The method according to claim 17, wherein the hydrogen carbonate comprises 90% to 98% by weight of the toothpaste. 19.7 The method of claim 18, wherein the fluoride additive comprises about 0.22 xi% sodium fluoride. 20. The method of claim 19 further comprising about 20.2% flavoring agent, sweetening agent, or mixture thereof.