JPS5883236A - Optical measuring method in automatic clinical and chemical analyzing device - Google Patents

Abstract

PURPOSE:To obtain an optical measuring method which eliminates adverse influence by stray light phenomena and can improve the reliability of the results of measurement markedly by moving prescribed amts. of reacting liquid intermittently and successively along prescribed routes, and performing the optical measurements to be carried out during the pause period of the intermittent movements at least every other times. CONSTITUTION:Reacting liquid is fed by each prescribed amt. into plural reaction measuring tubes 1, 2-n, and the tubes 1, 2-n made of a light transmittable material, for example, transparent glass, transparent plastics, etc. are disposed linearly in an optical measuring part of an automatic clinical and chemical analyzing device. The tubes 1, 2-n disposed in such a way are moved successively intermittently and are fed to an optical measuring device. The optical measurements of the liquids 1, 2-n are accomplished as follows: After the odd numbered places of the liquids 1, 3-n-1 of the reaction measuring tubes are optically measured with light source light K transmitted through the holes H1, H2-Hn/2 of a masking A, the masking A is moved by a motor M and is stopped so that the respective holes H1, H2-Hn of the masking A face the even numbered places of the tubes 2, 4-n. The light K is transmitted through said holes H1, H2-Hn/2 whereby the even numbered places of the liquids 2, 4-n are optically measured.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to an optical measurement method in an automatic clinical chemistry analyzer, and particularly relates to an optical measurement method in an automatic clinical chemistry analyzer that can completely eliminate the adverse effects of stray light on optical measurement results. .

Conventionally, optical measurements in automatic clinical chemistry analyzers have been carried out by, for example, preparing multiple cassettes that support multiple transparent reaction measurement tubes, and moving each cassette sequentially and intermittently along a predetermined path. In most cases, reagents are injected into each reaction measuring tube during movement, and then the reaction liquid is stirred and the reaction liquids in all reaction measuring tubes supported by each cassette are simultaneously measured optically. Ta.

However, in such a conventional optical measurement method, as shown in FIG. 1, the light source light λ1 . λ, . If the tubes 1.2-.- are made of transparent plastic, the light from the light source will be internally reflected, increasing the amount of light shielded from each other, and as a result, the reliability of measurement accuracy will be reduced. had.

This invention was made in view of the current situation, and
The purpose of this is to move a predetermined amount of the reaction solution intermittently along a predetermined path, and to perform at least every other optical measurement during the stop period between the intermittent movements, thereby eliminating the stray light phenomenon. The present invention aims to provide an optical measurement method in an automatic clinical chemistry analyzer that can significantly improve the reliability of measurement results.

Hereinafter, the present invention will be described in detail based on embodiments shown in the accompanying drawings.

In this example, the reaction liquid is collected in a plurality of reaction measurement tubes 1.2.
...n is injected in a predetermined amount at a time, and the reaction measuring tube 1.2...n, which is made of a translucent material such as transparent glass or transparent plastic, is used for optical measurement of an automatic clinical chemistry analyzer. arranged linearly in the section.

The reaction measuring tubes 1.2...n arranged in this manner are sequentially and intermittently moved and sent to the optical measuring device. The configuration of this optical measurement device is the same as that of a known optical measurement device, and is provided opposite to the reaction measurement tubes 1.2...n, and basically includes a light source, a masking A, and a sensing element. The information on the sensing element S is computer-processed by a computer or the like. The masking A is wound around the motor M in an endless manner as shown in FIG.
+ -Ha...5 are opened at predetermined intervals, that is, every other reaction measuring tube 1, 2.3...n. Therefore, optical measurements of reaction solutions 1, 2, . . . n are performed as follows.

That is, the odd-numbered reaction liquid 1.3...n- in the reaction measuring tube
1 is optically measured using the light source light K that has passed through the holes, h...
-Hn is stopped so that it faces the even-numbered reaction measuring tubes 2, 4...n. Then, the light source light K is passed through the holes H1, H,
... Even numbered reaction solution 2.4.''
Optically measure n.

In the present invention, the holes may be opened at intervals of not every other hole, but every two holes, every third hole, or the like.

In the above embodiment, after injecting the reaction liquid into the reaction measuring tubes 1.2...n, during intermittent movement, for example, the holding member may be lightly pressed to vibrate the reaction measuring tubes 1, 2...n. The reliability of the measurement accuracy can be further improved by giving the following values and defoaming the air bubbles adhering to the inside of the reaction measurement tube.

Since the present invention has the above-described configuration, the light source light does not enter other sensing elements due to diffused reflection from the reaction measurement tube, so that the stray light phenomenon can be completely eliminated, and the reliability of measurement accuracy can be greatly improved.

[Brief explanation of drawings]

FIG. 1 is an explanatory diagram showing an optical measurement method in a conventional clinical chemistry automatic analyzer, and FIGS. 2 and 3 are explanatory diagrams showing an optical measurement method in a clinical chemistry automatic analyzer according to the present invention. 1.2...n...Reaction measurement tube K...
・・・・・・・Light source, S・・・・・・・・・
Sensing element 1st I! I Figure 2 and Figure 3

Claims (1)

[Claims] A predetermined amount of reaction liquids are arranged in series, and the plurality of reaction liquids are sequentially and intermittently moved and sent to the optical measurement system 9. During the stop period between this intermittent movement and the next intermittent movement, the reaction liquid is In an optical measurement method for automatic clinical chemistry analysis, in which the optical measurement system is configured, the gap between the openings of the light source light transmission holes of the masking, which are arranged in correspondence with each reaction solution, is at least equal to An optical measurement method in an automatic clinical chemistry analyzer, characterized in that it is performed more than once.