JPS58124953A - Method and device for measuring and injecting of liquid - Google Patents

Abstract

PURPOSE:To measure liquid accurately without producing any waste by controlling the pressure of a pressure chamber into which one end of a measuring tube of which both ends are tapered off is inserted thereby sucking and injecting the liquid. CONSTITUTION:The measuring tube 30 of a measuring device 3 of which top and bottom end parts are tapered off is set in a measuring position, and when an operating member 4 is contracted, the volume in a pressure chamber 31 expands and the pressure in a pressure chamber 31 decreases; therefore, the liquid 2 in a liquid storage tank 1 is sucked into the tube 30. In this state, the pressure in the chamber 31 is so set as to be low slightly more than the measuring quantity of the tube 30; therefore, the sucked liquid 2 overflows slightly into the chamber 31. The overflowed liquid 2 is returned into the tank 1 by opening a cock 36. The device 3 is turned up to an injecting position by a link device 5, and the measured liquid 2 is injected into an injecting tube 6 by the pressing operation of the member 4.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention 1d relates to a liquid weighing/injection method and its apparatus, and more particularly to a liquid weighing/injection method and its apparatus suitable for a biochemical automatic analyzer.

In conventional biochemical automatic analyzers, when sucking a reagent from a reagent tank and injecting the reagent into an injection tube such as a reaction tube,
The required performance is, firstly, that there is no waste of reagents and that it is economical, and secondly, that the line from suction to injection of the reagents should not be contaminated by contamination with other types of reagents. Thirdly, the processing time from reagent suction to injection is short.

By the way, as a reagent weighing/injecting device for an automatic biochemical analyzer, plunger pump type and pipetting type are conventionally known.

However, with the conventional plunger pump type, there is a lot of wasted reagent when replacing the reagent, and
The pipetting method has the problem of being uneconomical, and because many reagents are processed with one suction tube, the reagent suction and injection lines become contaminated during reagent exchange. It has a fatal flaw in biochemical analysis and measurement.
Furthermore, even if any of the above-mentioned systems were incorporated into an automatic biochemical analyzer, there were various problems in that there was a limit to the processing time for one sample.

The present invention was devised in view of the current situation, and its purpose is to eliminate any waste of liquids such as reagents when aspirating or injecting liquids such as reagents, and to be able to weigh liquids such as reagents. In addition to being able to measure liquids extremely accurately, there is no risk of contamination of the suction and injection lines for liquids such as reagents, and the processing time from liquid suction to injection is significantly shortened. It is an object of the present invention to provide a liquid weighing/injection method and an apparatus therefor, which are particularly suitable for automatic biochemical analyzers.

In order to achieve such an object, in the present invention, a predetermined amount of liquid is sucked from the liquid storage section, and the sucked liquid is injected into an injection pipe arranged at a distance from the liquid storage section. The weighing and injection of a liquid constructed in this way is performed by using a weighing tube whose both ends are tapered, a pressure chamber into which one end of the weighing tube is inserted, and a pressure chamber in which the pressure inside the pressure chamber is adjusted. This is performed by pressure control of a device comprising an operating member to be controlled.

In the present invention, in order to carry out this method, liquid is sucked from the liquid storage section, and the sucked liquid is injected into an injection pipe arranged apart from the liquid storage section. A liquid weighing/injecting device configured to
Both ends of the weighing tube are tapered.

Hereinafter, the present invention will be described in detail based on embodiments shown in the accompanying drawings.

As shown in FIGS. 1 and 2, the liquid weighing/injection device according to this embodiment includes a liquid storage tank 1 that stores reagents, etc., and a predetermined amount of liquid 2 in the liquid storage tank 1. a liquid weighing device 3,
An operating member 4 that sends the liquid 2 sucked into the liquid weighing device 3 from the liquid weighing device 3 to the injection pipe 6 under pressure, and an operating member 4 that moves the operating member 4 and the liquid weighing device 3 to the injection pipe 6 position. It is composed of a link device 5 for moving.

The liquid storage tank 1 is formed in a box shape, and an opening 11 is formed approximately in the center of the upper lid 10, and a guide groove 12 for a weighing tube 30 of a liquid weighing device 3, which will be described later, is formed. has been done. Further, the bottom 13 of the liquid storage tank 1 has the opening 11
It is formed at an angle so that it is deepest at the position where liquid 2
Consideration has been given to improve weighing efficiency. In addition, 14 in the figure is a liquid injection port.

The liquid weighing device 3 includes a weighing tube 30 whose upper and lower ends are tapered, a pressure chamber 31 into which the upper end of the weighing tube 30 is removably and tightly inserted and held, and this pressure chamber 31. It is composed of an extensible operating member 4 attached to the top opening 32 and a drain device 35 connected to the deepest part of the inclined bottom 34 of the pressure chamber 31. A cock 36 is interposed in the middle to control the liquid 2 that overflows and accumulates in the pressure chamber 31 and returns it to the liquid storage tank 1. Incidentally, the reference numeral 37 in the figure indicates a seal packing.

Further, the weighing tube 30 is precisely formed so that a desired amount can be weighed, and after weighing, the liquid 2 in the weighing tube 30 does not drip and change the weighing tube. , as mentioned above, both ends are tapered.

The liquid weighing device 3 configured in this way has the above-mentioned liquid storage tank 1.
It has an opening lower formed in approximately the same shape and diameter as the opening 11 of the liquid storage tank 1, and is fitted and held in a movable frame 8 with a front opening installed over the opening part of the liquid storage tank 1. The movable frame 8 has link devices 5 each having one end pivotally supported on the side surface of the liquid storage tank 1.
The other ends of the link arms 5a and 5b are pivotally supported,
The liquid weighing device 3 is configured to rotate together with the movable pedestal 8 via a link device 5 from a liquid weighing position to a position where the injection tube 6 is placed.

Next, the operation of the liquid measuring/injecting device will be explained.

First, as shown in FIG. 2, the weighing tube 3 of the liquid weighing device 3 is
0 is set at the liquid weighing position and the operating member 4 is contracted by an appropriate pressing means, the volume in the pressure chamber 31 expands and the pressure in the pressure chamber 31 decreases, so that the liquid 2 in the liquid storage tank 1 is is sucked into the weighing tube 30. At this time, the internal pressure necessary for suctioning the liquid 2 in the pressure chamber 31 is set to be slightly lower than the amount weighed by the weighing tube 30.
Since the liquid 2 sucked into the pressure chamber 31 slightly overflows into the pressure chamber 31, the amount sucked and weighed in the weighing tube 30 will never be too much or too little, and will always remain constant. The liquid 2 stored in the pressure chamber 31 due to overflow is returned to the liquid storage tank 1 by opening the cock 36.

After sucking the liquid 2 into the weighing tube 30 in this manner, the liquid weighing device 3 is rotated to the liquid injection position via the link device 5 operated by a known timing circuit, and the liquid weighing device 3 is rotated to the liquid injection position.
The liquid 2 weighed into the liquid 2 is injected from the weighing tube 30 into the injection tube 6 by pressing the operating member 4 .

In the above embodiment, a case has been described in which the liquid weighing device 3 and the operating member 4 are moved to the liquid injection position by the link device 5, but in this invention, the liquid storage tank 1 It may be configured such that it is moved backward by the link device 5 and moved downwardly of the injection tube 6 and the weighing tube 30 in synchronization with this.

In addition, in the above embodiment, the weighing tube 30 is connected to the pressure chamber 31.
The explanation has been given by taking as an example a case in which the weighing tube 30 with a different weighing amount can be easily attached by being removably inserted into the weighing tube 30 and the pressure chamber 31. It may be formed integrally with.

Furthermore, in the above embodiment, the operating member 4 is made of only an expandable and contractible material, for example, a rubber member. However, the pressure inside the pressure chamber 31 may be maintained constant, the overflow amount of the liquid 2 may be constant, and the weighing processing time may be constant.

Since this invention includes the above configuration, especially when applied to a biochemical automatic analyzer, there is no wastage of reagents, and the sample can be weighed with extremely high precision. In addition to being able to be dedicated to each reagent, a single weighing tube can be used to aspirate and inject reagents, so there is no chance of contamination of the reagent aspiration/injection line, and the processing time from reagent aspiration to injection can be shortened. This effect is achieved.

[Brief explanation of drawings]

The drawings show one embodiment of the present invention, and FIG. 1 is an exploded perspective view of a liquid weighing and injection device, and FIG. 2 is a cross-sectional explanatory view showing the operating state of the device. 1...Liquid storage tank (liquid storage section) 2...Liquid 4...
・Operation member 6... Injection pipe 30...
Weighing tube 31...Pressure chamber patent applicant Nippon Techtron Co., Ltd. Engraving of the drawing (no changes to the content) Amendment to the procedure for drawing Y'2' (self-motivated) Commissioner of the Japan Patent Office Shima 1) Haruki-dono 1. Indication of the case 1982 Patent No. 008040 2. Name of the invention Liquid weighing/injection method and apparatus 3. Person making the amendment Relationship to the case Patent applicant address 4-13 Nakamachi, Koganei City, Tokyo No. 14 4. Date of amendment order (voluntary) - 15. Drawings subject to amendment 6゜Contents of amendment

Claims (1)

[Claims] 1) A liquid configured to suck a predetermined amount of liquid from a liquid storage section and inject the sucked liquid into an injection pipe arranged at a distance from the liquid storage section. The liquid weighing/injection method uses a weighing tube whose both ends are tapered and a pressure chamber into which one end of the weighing tube is inserted. 1. A method for weighing and injecting a liquid, characterized in that the method is carried out by pressure control of a device comprising an operating member for controlling the pressure of the liquid. 2) A liquid weighing/injection device configured to suck a predetermined amount of liquid from a liquid storage part and inject the sucked liquid into an injection pipe arranged apart from the liquid storage part. The liquid weighing/injecting device is composed of a weighing tube, a pressure chamber into which one end of the weighing tube is inserted, and an operating section for controlling the pressure inside the pressure chamber. A liquid weighing/injecting device characterized in that both ends of the weighing tube are tapered.