JPS5799571A - Nicomol having novel crystal form - Google Patents

Nicomol having novel crystal form

Info

Publication number
JPS5799571A
JPS5799571A JP17784880A JP17784880A JPS5799571A JP S5799571 A JPS5799571 A JP S5799571A JP 17784880 A JP17784880 A JP 17784880A JP 17784880 A JP17784880 A JP 17784880A JP S5799571 A JPS5799571 A JP S5799571A
Authority
JP
Japan
Prior art keywords
additive
crystal form
titled compound
nicomol
novel crystal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP17784880A
Other languages
Japanese (ja)
Other versions
JPS6348867B2 (en
Inventor
Tsutomu Irikura
Hiroshi Uchida
Atsushi Imai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyorin Pharmaceutical Co Ltd
Original Assignee
Kyorin Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Pharmaceutical Co Ltd filed Critical Kyorin Pharmaceutical Co Ltd
Priority to JP17784880A priority Critical patent/JPS5799571A/en
Publication of JPS5799571A publication Critical patent/JPS5799571A/en
Publication of JPS6348867B2 publication Critical patent/JPS6348867B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:2,2,6,6-Tetrakis(nicotinoyloxymethyl)cyclohexanol having β form crystal form and a characteristic diffraction pattern of X-rays.
USE: Useful as a drug having lipid metabolism improving and peripheral circulation promoting action. Having high solubility, stable with time, having improved absorption.
PROCESS: Amorphous miconol is reacted with a pharmaceutically acceptable additive under heating at ≤150°C, to give the titled compound. A hydrophilic high polymer compound, sugaralcohol, bile acid, higher fatty acid, wax, etc. may be cited as the additive, and the blending ratio of the titled compound:additive is preferably (1:0.01)W(1:10).
COPYRIGHT: (C)1982,JPO&Japio
JP17784880A 1980-12-15 1980-12-15 Nicomol having novel crystal form Granted JPS5799571A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP17784880A JPS5799571A (en) 1980-12-15 1980-12-15 Nicomol having novel crystal form

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP17784880A JPS5799571A (en) 1980-12-15 1980-12-15 Nicomol having novel crystal form

Publications (2)

Publication Number Publication Date
JPS5799571A true JPS5799571A (en) 1982-06-21
JPS6348867B2 JPS6348867B2 (en) 1988-09-30

Family

ID=16038157

Family Applications (1)

Application Number Title Priority Date Filing Date
JP17784880A Granted JPS5799571A (en) 1980-12-15 1980-12-15 Nicomol having novel crystal form

Country Status (1)

Country Link
JP (1) JPS5799571A (en)

Also Published As

Publication number Publication date
JPS6348867B2 (en) 1988-09-30

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