JPS5785346A - Cyclohexanecarboxylic acid derivative - Google Patents

Cyclohexanecarboxylic acid derivative

Info

Publication number
JPS5785346A
JPS5785346A JP16290980A JP16290980A JPS5785346A JP S5785346 A JPS5785346 A JP S5785346A JP 16290980 A JP16290980 A JP 16290980A JP 16290980 A JP16290980 A JP 16290980A JP S5785346 A JPS5785346 A JP S5785346A
Authority
JP
Japan
Prior art keywords
formula
compound
acid derivative
cyclohexanecarboxylic acid
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP16290980A
Other languages
Japanese (ja)
Other versions
JPS6353984B2 (en
Inventor
Kanji Noda
Akira Nakagawa
Toshiharu Motomura
Masayoshi Tsuji
Yuji Shimozono
Hiroyuki Ide
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hisamitsu Pharmaceutical Co Inc
Original Assignee
Hisamitsu Pharmaceutical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co Inc filed Critical Hisamitsu Pharmaceutical Co Inc
Priority to JP16290980A priority Critical patent/JPS5785346A/en
Publication of JPS5785346A publication Critical patent/JPS5785346A/en
Publication of JPS6353984B2 publication Critical patent/JPS6353984B2/ja
Granted legal-status Critical Current

Links

Abstract

NEW MATERIAL:A compound of formula I(R is lower alkyl; A is aryl, pyridyl).
EXAMPLE: Trans-4-Benzylaminomethylcyclohexanecarboxylic acid.
USE: It is used as a prophyractic against or remedy for allergic diseases such as nephritis or rheumatism, because of its remarkable anticomplementary activity. Further, it has also antiplasmin and antitumor activities and used as a medicine.
PREPARATION: The reductive condensation reaction between tranexamic acid of formula II or its ester derivative and an aromatic aldehyde of formula III is conducted in an organic solvent such as methanol in the presence of a catalyst such as palladium on carbon at room temperature or under heating using hydrogen at normal or elevated pressure (0.1W10kg/cm2) to give the compound of formula I.
COPYRIGHT: (C)1982,JPO&Japio
JP16290980A 1980-11-18 1980-11-18 Cyclohexanecarboxylic acid derivative Granted JPS5785346A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16290980A JPS5785346A (en) 1980-11-18 1980-11-18 Cyclohexanecarboxylic acid derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16290980A JPS5785346A (en) 1980-11-18 1980-11-18 Cyclohexanecarboxylic acid derivative

Publications (2)

Publication Number Publication Date
JPS5785346A true JPS5785346A (en) 1982-05-28
JPS6353984B2 JPS6353984B2 (en) 1988-10-26

Family

ID=15763526

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16290980A Granted JPS5785346A (en) 1980-11-18 1980-11-18 Cyclohexanecarboxylic acid derivative

Country Status (1)

Country Link
JP (1) JPS5785346A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60163813A (en) * 1984-02-04 1985-08-26 Morishita Jintan Kk Antiplasmin drug
WO2006117762A2 (en) 2005-05-03 2006-11-09 Ranbaxy Laboratories Limited Antimicrobial agents
JP2009533315A (en) * 2006-04-10 2009-09-17 ランバクシー ラボラトリーズ リミテッド Antibacterial agent

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4965825A (en) 1981-11-03 1990-10-23 The Personalized Mass Media Corporation Signal processing apparatus and methods
JPH0522215U (en) * 1991-09-02 1993-03-23 本田技研工業株式会社 External pipe holding structure

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60163813A (en) * 1984-02-04 1985-08-26 Morishita Jintan Kk Antiplasmin drug
WO2006117762A2 (en) 2005-05-03 2006-11-09 Ranbaxy Laboratories Limited Antimicrobial agents
WO2006117762A3 (en) * 2005-05-03 2007-02-08 Ranbaxy Lab Ltd Antimicrobial agents
US8076370B2 (en) 2005-05-03 2011-12-13 Ranbaxy Laboratories Limited Antimicrobial agents
AU2006242824B2 (en) * 2005-05-03 2012-03-29 Ranbaxy Laboratories Limited Antimicrobial agents
JP2009533315A (en) * 2006-04-10 2009-09-17 ランバクシー ラボラトリーズ リミテッド Antibacterial agent

Also Published As

Publication number Publication date
JPS6353984B2 (en) 1988-10-26

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