JPS5785346A - Cyclohexanecarboxylic acid derivative - Google Patents
Cyclohexanecarboxylic acid derivativeInfo
- Publication number
- JPS5785346A JPS5785346A JP16290980A JP16290980A JPS5785346A JP S5785346 A JPS5785346 A JP S5785346A JP 16290980 A JP16290980 A JP 16290980A JP 16290980 A JP16290980 A JP 16290980A JP S5785346 A JPS5785346 A JP S5785346A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- acid derivative
- cyclohexanecarboxylic acid
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:A compound of formula I(R is lower alkyl; A is aryl, pyridyl).
EXAMPLE: Trans-4-Benzylaminomethylcyclohexanecarboxylic acid.
USE: It is used as a prophyractic against or remedy for allergic diseases such as nephritis or rheumatism, because of its remarkable anticomplementary activity. Further, it has also antiplasmin and antitumor activities and used as a medicine.
PREPARATION: The reductive condensation reaction between tranexamic acid of formula II or its ester derivative and an aromatic aldehyde of formula III is conducted in an organic solvent such as methanol in the presence of a catalyst such as palladium on carbon at room temperature or under heating using hydrogen at normal or elevated pressure (0.1W10kg/cm2) to give the compound of formula I.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16290980A JPS5785346A (en) | 1980-11-18 | 1980-11-18 | Cyclohexanecarboxylic acid derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16290980A JPS5785346A (en) | 1980-11-18 | 1980-11-18 | Cyclohexanecarboxylic acid derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5785346A true JPS5785346A (en) | 1982-05-28 |
JPS6353984B2 JPS6353984B2 (en) | 1988-10-26 |
Family
ID=15763526
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP16290980A Granted JPS5785346A (en) | 1980-11-18 | 1980-11-18 | Cyclohexanecarboxylic acid derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5785346A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60163813A (en) * | 1984-02-04 | 1985-08-26 | Morishita Jintan Kk | Antiplasmin drug |
WO2006117762A2 (en) | 2005-05-03 | 2006-11-09 | Ranbaxy Laboratories Limited | Antimicrobial agents |
JP2009533315A (en) * | 2006-04-10 | 2009-09-17 | ランバクシー ラボラトリーズ リミテッド | Antibacterial agent |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4965825A (en) | 1981-11-03 | 1990-10-23 | The Personalized Mass Media Corporation | Signal processing apparatus and methods |
JPH0522215U (en) * | 1991-09-02 | 1993-03-23 | 本田技研工業株式会社 | External pipe holding structure |
-
1980
- 1980-11-18 JP JP16290980A patent/JPS5785346A/en active Granted
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60163813A (en) * | 1984-02-04 | 1985-08-26 | Morishita Jintan Kk | Antiplasmin drug |
WO2006117762A2 (en) | 2005-05-03 | 2006-11-09 | Ranbaxy Laboratories Limited | Antimicrobial agents |
WO2006117762A3 (en) * | 2005-05-03 | 2007-02-08 | Ranbaxy Lab Ltd | Antimicrobial agents |
US8076370B2 (en) | 2005-05-03 | 2011-12-13 | Ranbaxy Laboratories Limited | Antimicrobial agents |
AU2006242824B2 (en) * | 2005-05-03 | 2012-03-29 | Ranbaxy Laboratories Limited | Antimicrobial agents |
JP2009533315A (en) * | 2006-04-10 | 2009-09-17 | ランバクシー ラボラトリーズ リミテッド | Antibacterial agent |
Also Published As
Publication number | Publication date |
---|---|
JPS6353984B2 (en) | 1988-10-26 |
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