JPS577451A - Production of aminochlorophenol - Google Patents
Production of aminochlorophenolInfo
- Publication number
- JPS577451A JPS577451A JP7996480A JP7996480A JPS577451A JP S577451 A JPS577451 A JP S577451A JP 7996480 A JP7996480 A JP 7996480A JP 7996480 A JP7996480 A JP 7996480A JP S577451 A JPS577451 A JP S577451A
- Authority
- JP
- Japan
- Prior art keywords
- reaction
- ammonia
- monobromochlorophenol
- produce
- titled compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: The reaction between a monobromochlorophenol and ammonia in the presence of a copper catalyst is conducted in a specific temperature range to produce the titled compound that is used as a medicine by usual purification operations in high yield.
CONSTITUTION: A monobromochlorophenol such as 2-chloro-4-bromophenol is mixed with ammonia and they are made to react in the presence of a copper catalyst such as powdered copper with heat at 50W120°C to produce the titled compound. As an ammonia source, is used its aqueous solution of higher than 28% concentration or liquid ammonia and the amount employed for the reaction is usually more than 5mol/mol of the monobromochlorophenol. The reaction is effected in a tightly sealed reactor under the autogeneous pressure caused by heating.
EFFECT: Bromine atoms are selectively substituted with amino groups. The reaction is mild.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7996480A JPS577451A (en) | 1980-06-13 | 1980-06-13 | Production of aminochlorophenol |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7996480A JPS577451A (en) | 1980-06-13 | 1980-06-13 | Production of aminochlorophenol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS577451A true JPS577451A (en) | 1982-01-14 |
Family
ID=13704986
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP7996480A Pending JPS577451A (en) | 1980-06-13 | 1980-06-13 | Production of aminochlorophenol |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS577451A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7077399B2 (en) | 2001-12-14 | 2006-07-18 | Unirec Co., Ltd. | Chip collecting machine |
-
1980
- 1980-06-13 JP JP7996480A patent/JPS577451A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7077399B2 (en) | 2001-12-14 | 2006-07-18 | Unirec Co., Ltd. | Chip collecting machine |
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