JPS5756430A - Live virus vaccine for canine parainfluenza - Google Patents

Live virus vaccine for canine parainfluenza

Info

Publication number
JPS5756430A
JPS5756430A JP13134280A JP13134280A JPS5756430A JP S5756430 A JPS5756430 A JP S5756430A JP 13134280 A JP13134280 A JP 13134280A JP 13134280 A JP13134280 A JP 13134280A JP S5756430 A JPS5756430 A JP S5756430A
Authority
JP
Japan
Prior art keywords
viruses
vaccine
virus
cells
dog
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP13134280A
Other languages
Japanese (ja)
Inventor
Fumiari Sasaki
Masahisa Nakai
Kazuhisa Hiramatsu
Masayuki Ajiki
Keizo Takamura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Priority to JP13134280A priority Critical patent/JPS5756430A/en
Publication of JPS5756430A publication Critical patent/JPS5756430A/en
Pending legal-status Critical Current

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

PURPOSE: To provide a live virus vaccine effective to the respiratory diseases caused by infection with canine parainfluenza viruses and having high safety, by usig attenuated virus obtained by the extended tissue subculture of viruses.
CONSTITUTION: Viruses separated from a dog affected with respiratory diseases through the first-generation dog kidney (DK)culture cells, is subcultured for four generations in DK culture cells, and then subcultured in the established cells of the kidney of green monkey (Cerocopithecus aethiops sabaeus)(Vero cell) at 30±5°C. for ≥30 generations. The resultant viruses are inoculated in Vero cells, and cultured at 30°C. At the peak of the proliferation of the virus, the infected culture liquid is collected, mixed with the sterilized liquid consisting of a protecting agent (e.g. lactose) and purified water, and freeze-dried to obtain the titled live vaccine. It has remarkable effectiveness after three weeks from inoculation of the vaccine even by the aggresive test using the attenuated CPI virus. The vaccine gives no side effect in the test using a dog negative to antibody, and the high safety.
COPYRIGHT: (C)1982,JPO&Japio
JP13134280A 1980-09-19 1980-09-19 Live virus vaccine for canine parainfluenza Pending JPS5756430A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP13134280A JPS5756430A (en) 1980-09-19 1980-09-19 Live virus vaccine for canine parainfluenza

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13134280A JPS5756430A (en) 1980-09-19 1980-09-19 Live virus vaccine for canine parainfluenza

Publications (1)

Publication Number Publication Date
JPS5756430A true JPS5756430A (en) 1982-04-05

Family

ID=15055693

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13134280A Pending JPS5756430A (en) 1980-09-19 1980-09-19 Live virus vaccine for canine parainfluenza

Country Status (1)

Country Link
JP (1) JPS5756430A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60206584A (en) * 1984-03-27 1985-10-18 グロトンズ　メタルフオ−ミング　システムス，インコ−ポレイテツド Welding machine of half-finished product for wheel rim of car
JPH02144277U (en) * 1989-04-28 1990-12-06
JP2009506050A (en) * 2005-08-25 2009-02-12 メリアル リミテッド Canine influenza vaccine
US7682619B2 (en) 2006-04-06 2010-03-23 Cornell Research Foundation, Inc. Canine influenza virus
CN112899240A (en) * 2021-02-24 2021-06-04 北京华夏兴洋生物科技有限公司 Canine parainfluenza virus attenuated strain, application and vaccine thereof

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60206584A (en) * 1984-03-27 1985-10-18 グロトンズ　メタルフオ−ミング　システムス，インコ−ポレイテツド Welding machine of half-finished product for wheel rim of car
JPH033548B2 (en) * 1984-03-27 1991-01-18 Gurotonzu Metarufuoomingu Shisutemusu Inc
JPH02144277U (en) * 1989-04-28 1990-12-06
JP2009506050A (en) * 2005-08-25 2009-02-12 メリアル リミテッド Canine influenza vaccine
US7682619B2 (en) 2006-04-06 2010-03-23 Cornell Research Foundation, Inc. Canine influenza virus
CN112899240A (en) * 2021-02-24 2021-06-04 北京华夏兴洋生物科技有限公司 Canine parainfluenza virus attenuated strain, application and vaccine thereof
CN112899240B (en) * 2021-02-24 2022-07-29 北京华夏兴洋生物科技有限公司 Canine parainfluenza virus low virulent strain, application thereof and vaccine

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