JPS5742852A - Erythrocyte sensitized with antibody of polysaccharide of hemolytic streptococcus - Google Patents

Erythrocyte sensitized with antibody of polysaccharide of hemolytic streptococcus

Info

Publication number
JPS5742852A
JPS5742852A JP55117032A JP11703280A JPS5742852A JP S5742852 A JPS5742852 A JP S5742852A JP 55117032 A JP55117032 A JP 55117032A JP 11703280 A JP11703280 A JP 11703280A JP S5742852 A JPS5742852 A JP S5742852A
Authority
JP
Japan
Prior art keywords
antibody
erythrocyte
sensitized
hemolytic
polysaccharide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP55117032A
Other languages
Japanese (ja)
Inventor
Tetsuo Tomiyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Seikagaku Corp
Original Assignee
Seikagaku Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seikagaku Corp filed Critical Seikagaku Corp
Priority to JP55117032A priority Critical patent/JPS5742852A/en
Publication of JPS5742852A publication Critical patent/JPS5742852A/en
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56944Streptococcus

Abstract

PURPOSE:To obtain sensitized erythrocytes by which hemolytic streptococcus inflections disease can be diagnosed surely at early stage of infection by a simple procedure, by coupling as antibody consisting of polysaccharide of hemolytic streptococci to erythrocytes by means of a coupling agent. CONSTITUTION:An animal such as a rabbit and a goat is immunized with a hermolyic streptococci, and an antibody of cells of hemolytic streptococci thus obtained is purified soecifically, then an antibody of polysaccharide of hemolytic streptococci (PS-antibody) is separated. Next, the PS-antibody is brought into contact with a solution of an erythrocyte (preferably a fixed erythrocyte) treated with a coupling agent (e.g. tannin), and coupled it to produce the erythrocyte sensitized with the PS-antibody. As the sensitized erythrocyte mentioned above is agglutinated by a polysacchride antigen of a hemolytic streptococcus, the polysacchride antigen is detected by reverse passive hemagglutination, the infectious disease of hemolytic streptococci can be diagnosed easily at the early stage.
JP55117032A 1980-08-27 1980-08-27 Erythrocyte sensitized with antibody of polysaccharide of hemolytic streptococcus Pending JPS5742852A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP55117032A JPS5742852A (en) 1980-08-27 1980-08-27 Erythrocyte sensitized with antibody of polysaccharide of hemolytic streptococcus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55117032A JPS5742852A (en) 1980-08-27 1980-08-27 Erythrocyte sensitized with antibody of polysaccharide of hemolytic streptococcus

Publications (1)

Publication Number Publication Date
JPS5742852A true JPS5742852A (en) 1982-03-10

Family

ID=14701751

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55117032A Pending JPS5742852A (en) 1980-08-27 1980-08-27 Erythrocyte sensitized with antibody of polysaccharide of hemolytic streptococcus

Country Status (1)

Country Link
JP (1) JPS5742852A (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108117586A (en) * 2010-08-10 2018-06-05 洛桑聚合联合学院 Erythrocyte binding therapeutic agent
RU2749026C1 (en) * 2020-06-03 2021-06-03 федеральное государственное бюджетное образовательное учреждение высшего образования "Ставропольский государственный аграрный университет" Method for diagnosis of isoimmunization in animals
US11246943B2 (en) 2010-08-10 2022-02-15 École Polytechnique Fédérale De Lausanne (Epfl) Antigen-specific tolerance and compositions for induction of same
US11253579B2 (en) 2017-06-16 2022-02-22 The University Of Chicago Compositions and methods for inducing immune tolerance
US11654188B2 (en) 2014-02-21 2023-05-23 Ecole Polytechnique Federale De Lausanne (Epfl) Glycotargeting therapeutics
US11666638B2 (en) 2014-02-21 2023-06-06 Ecole Polytechnique Federale De Lausanne (Epfl) Glycotargeting therapeutics
US11793882B2 (en) 2014-02-21 2023-10-24 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics
US11801305B2 (en) 2014-02-21 2023-10-31 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108117586A (en) * 2010-08-10 2018-06-05 洛桑聚合联合学院 Erythrocyte binding therapeutic agent
US11246943B2 (en) 2010-08-10 2022-02-15 École Polytechnique Fédérale De Lausanne (Epfl) Antigen-specific tolerance and compositions for induction of same
US11654188B2 (en) 2014-02-21 2023-05-23 Ecole Polytechnique Federale De Lausanne (Epfl) Glycotargeting therapeutics
US11666638B2 (en) 2014-02-21 2023-06-06 Ecole Polytechnique Federale De Lausanne (Epfl) Glycotargeting therapeutics
US11793882B2 (en) 2014-02-21 2023-10-24 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics
US11801305B2 (en) 2014-02-21 2023-10-31 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics
US11253579B2 (en) 2017-06-16 2022-02-22 The University Of Chicago Compositions and methods for inducing immune tolerance
RU2749026C1 (en) * 2020-06-03 2021-06-03 федеральное государственное бюджетное образовательное учреждение высшего образования "Ставропольский государственный аграрный университет" Method for diagnosis of isoimmunization in animals

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