JPS5742852A - Erythrocyte sensitized with antibody of polysaccharide of hemolytic streptococcus - Google Patents
Erythrocyte sensitized with antibody of polysaccharide of hemolytic streptococcusInfo
- Publication number
- JPS5742852A JPS5742852A JP55117032A JP11703280A JPS5742852A JP S5742852 A JPS5742852 A JP S5742852A JP 55117032 A JP55117032 A JP 55117032A JP 11703280 A JP11703280 A JP 11703280A JP S5742852 A JPS5742852 A JP S5742852A
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- erythrocyte
- sensitized
- hemolytic
- polysaccharide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/56944—Streptococcus
Abstract
PURPOSE:To obtain sensitized erythrocytes by which hemolytic streptococcus inflections disease can be diagnosed surely at early stage of infection by a simple procedure, by coupling as antibody consisting of polysaccharide of hemolytic streptococci to erythrocytes by means of a coupling agent. CONSTITUTION:An animal such as a rabbit and a goat is immunized with a hermolyic streptococci, and an antibody of cells of hemolytic streptococci thus obtained is purified soecifically, then an antibody of polysaccharide of hemolytic streptococci (PS-antibody) is separated. Next, the PS-antibody is brought into contact with a solution of an erythrocyte (preferably a fixed erythrocyte) treated with a coupling agent (e.g. tannin), and coupled it to produce the erythrocyte sensitized with the PS-antibody. As the sensitized erythrocyte mentioned above is agglutinated by a polysacchride antigen of a hemolytic streptococcus, the polysacchride antigen is detected by reverse passive hemagglutination, the infectious disease of hemolytic streptococci can be diagnosed easily at the early stage.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55117032A JPS5742852A (en) | 1980-08-27 | 1980-08-27 | Erythrocyte sensitized with antibody of polysaccharide of hemolytic streptococcus |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55117032A JPS5742852A (en) | 1980-08-27 | 1980-08-27 | Erythrocyte sensitized with antibody of polysaccharide of hemolytic streptococcus |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5742852A true JPS5742852A (en) | 1982-03-10 |
Family
ID=14701751
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP55117032A Pending JPS5742852A (en) | 1980-08-27 | 1980-08-27 | Erythrocyte sensitized with antibody of polysaccharide of hemolytic streptococcus |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5742852A (en) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108117586A (en) * | 2010-08-10 | 2018-06-05 | 洛桑聚合联合学院 | Erythrocyte binding therapeutic agent |
RU2749026C1 (en) * | 2020-06-03 | 2021-06-03 | федеральное государственное бюджетное образовательное учреждение высшего образования "Ставропольский государственный аграрный университет" | Method for diagnosis of isoimmunization in animals |
US11246943B2 (en) | 2010-08-10 | 2022-02-15 | École Polytechnique Fédérale De Lausanne (Epfl) | Antigen-specific tolerance and compositions for induction of same |
US11253579B2 (en) | 2017-06-16 | 2022-02-22 | The University Of Chicago | Compositions and methods for inducing immune tolerance |
US11654188B2 (en) | 2014-02-21 | 2023-05-23 | Ecole Polytechnique Federale De Lausanne (Epfl) | Glycotargeting therapeutics |
US11666638B2 (en) | 2014-02-21 | 2023-06-06 | Ecole Polytechnique Federale De Lausanne (Epfl) | Glycotargeting therapeutics |
US11793882B2 (en) | 2014-02-21 | 2023-10-24 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
US11801305B2 (en) | 2014-02-21 | 2023-10-31 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
-
1980
- 1980-08-27 JP JP55117032A patent/JPS5742852A/en active Pending
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108117586A (en) * | 2010-08-10 | 2018-06-05 | 洛桑聚合联合学院 | Erythrocyte binding therapeutic agent |
US11246943B2 (en) | 2010-08-10 | 2022-02-15 | École Polytechnique Fédérale De Lausanne (Epfl) | Antigen-specific tolerance and compositions for induction of same |
US11654188B2 (en) | 2014-02-21 | 2023-05-23 | Ecole Polytechnique Federale De Lausanne (Epfl) | Glycotargeting therapeutics |
US11666638B2 (en) | 2014-02-21 | 2023-06-06 | Ecole Polytechnique Federale De Lausanne (Epfl) | Glycotargeting therapeutics |
US11793882B2 (en) | 2014-02-21 | 2023-10-24 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
US11801305B2 (en) | 2014-02-21 | 2023-10-31 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
US11253579B2 (en) | 2017-06-16 | 2022-02-22 | The University Of Chicago | Compositions and methods for inducing immune tolerance |
RU2749026C1 (en) * | 2020-06-03 | 2021-06-03 | федеральное государственное бюджетное образовательное учреждение высшего образования "Ставропольский государственный аграрный университет" | Method for diagnosis of isoimmunization in animals |
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