JPS5724310A - Cholesterol reducing agent - Google Patents
Cholesterol reducing agentInfo
- Publication number
- JPS5724310A JPS5724310A JP9817480A JP9817480A JPS5724310A JP S5724310 A JPS5724310 A JP S5724310A JP 9817480 A JP9817480 A JP 9817480A JP 9817480 A JP9817480 A JP 9817480A JP S5724310 A JPS5724310 A JP S5724310A
- Authority
- JP
- Japan
- Prior art keywords
- resin
- reducing agent
- cholesterol reducing
- cholesterol
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE:A cholesterol reducing agent, containing an anion exchange resin having a specific imidazole salt as functional groups essentially, having a high selective adsorbability for bile acids and no bad smell without adsorbing useful substances, e.g. vitamins. CONSTITUTION:A cholesterol reducing agent containing an anion exchange resin which is a copolymer of a reaction product between a halomethyloxirane compound of formula I (R is H or CH3; X is halogen) with an imidazole of formula II (R1 is H; R2 is H, 1-11C alkyl, etc.; R3 and R4 are H or 1-3C alkyl) and a polyfunctional epoxy resin having two or more oxirane rings and an epoxy equivalent of 100-600 as an active constituent. The resin is a water-insoluble resin having an imidazole salt in which the counter ion is one selected from X<->, OH<-> and 1/2 (SO4)<2-> as functional groups, a moisture content of 30-90% and a particle diameter <=50 mesh. The oral administration of the agent in a dose of 1-30g per adult a day permits the reduction of the cholesterol.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9817480A JPS5724310A (en) | 1980-07-19 | 1980-07-19 | Cholesterol reducing agent |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9817480A JPS5724310A (en) | 1980-07-19 | 1980-07-19 | Cholesterol reducing agent |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5724310A true JPS5724310A (en) | 1982-02-08 |
JPS6366290B2 JPS6366290B2 (en) | 1988-12-20 |
Family
ID=14212674
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP9817480A Granted JPS5724310A (en) | 1980-07-19 | 1980-07-19 | Cholesterol reducing agent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5724310A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0098884A1 (en) * | 1982-01-18 | 1984-01-25 | Mitsubishi Petrochemical Co., Ltd. | Cholesterol lowering drug |
US4555000A (en) * | 1983-06-07 | 1985-11-26 | Mitsubishi Denki Kabushiki Kaisha | Apparatus for operating an elevator |
US4662479A (en) * | 1985-01-22 | 1987-05-05 | Mitsubishi Denki Kabushiki Kaisha | Operating apparatus for elevator |
JPH07149657A (en) * | 1988-06-24 | 1995-06-13 | Upjohn Co:The | Pulverized hydrochloric acid salt of cholestipol and medicine composition for anti-hypercholesterolemia wherein it is active ingredient |
-
1980
- 1980-07-19 JP JP9817480A patent/JPS5724310A/en active Granted
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0098884A1 (en) * | 1982-01-18 | 1984-01-25 | Mitsubishi Petrochemical Co., Ltd. | Cholesterol lowering drug |
US4555000A (en) * | 1983-06-07 | 1985-11-26 | Mitsubishi Denki Kabushiki Kaisha | Apparatus for operating an elevator |
US4662479A (en) * | 1985-01-22 | 1987-05-05 | Mitsubishi Denki Kabushiki Kaisha | Operating apparatus for elevator |
JPH07149657A (en) * | 1988-06-24 | 1995-06-13 | Upjohn Co:The | Pulverized hydrochloric acid salt of cholestipol and medicine composition for anti-hypercholesterolemia wherein it is active ingredient |
Also Published As
Publication number | Publication date |
---|---|
JPS6366290B2 (en) | 1988-12-20 |
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