JPS5721367A - Germanium compound of proline derivative and its preparation - Google Patents

Germanium compound of proline derivative and its preparation

Info

Publication number
JPS5721367A
JPS5721367A JP9648880A JP9648880A JPS5721367A JP S5721367 A JPS5721367 A JP S5721367A JP 9648880 A JP9648880 A JP 9648880A JP 9648880 A JP9648880 A JP 9648880A JP S5721367 A JPS5721367 A JP S5721367A
Authority
JP
Japan
Prior art keywords
proline derivative
preparation
formula
germanium
germanium compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP9648880A
Other languages
Japanese (ja)
Inventor
Hironobu Sato
Hiroyuki Koike
Nobuaki Kitahara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Priority to JP9648880A priority Critical patent/JPS5721367A/en
Publication of JPS5721367A publication Critical patent/JPS5721367A/en
Pending legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

NEW MATERIAL:Germanium compounds of proline derivative of formula I (R1 is hydroxyl, lower alkoxy, amino; R2 is H, alkyl).
EXAMPLE: Germanium tetra[3-(2-carboxy-1-prolidinyl)-3-oxopropylmercaptate].
USE: Antihypertensive: they have high activity of inhibiting enzymes transforming angiotensin. The oral administration is preferred.
PREPARATION: The reaction between a proline derivative of formula II and germanium oxide affords the compound of formula I.
COPYRIGHT: (C)1982,JPO&Japio
JP9648880A 1980-07-15 1980-07-15 Germanium compound of proline derivative and its preparation Pending JPS5721367A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP9648880A JPS5721367A (en) 1980-07-15 1980-07-15 Germanium compound of proline derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9648880A JPS5721367A (en) 1980-07-15 1980-07-15 Germanium compound of proline derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS5721367A true JPS5721367A (en) 1982-02-04

Family

ID=14166450

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9648880A Pending JPS5721367A (en) 1980-07-15 1980-07-15 Germanium compound of proline derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS5721367A (en)

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