JPS57209228A - Hemolytic streptococcus m-protein - Google Patents
Hemolytic streptococcus m-proteinInfo
- Publication number
- JPS57209228A JPS57209228A JP9306181A JP9306181A JPS57209228A JP S57209228 A JPS57209228 A JP S57209228A JP 9306181 A JP9306181 A JP 9306181A JP 9306181 A JP9306181 A JP 9306181A JP S57209228 A JPS57209228 A JP S57209228A
- Authority
- JP
- Japan
- Prior art keywords
- serum
- protein
- immunized
- group
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
PURPOSE: A serum is collected from a nonhuman animal which is immunized with M-protein to produce the titled protein and vaccine used in prevention and treatment for infections caused by group-A hemolytic streptococci.
CONSTITUTION: A nonhuman animal is immunized with M-protein that has following physical and chemical properties: appearance, white powder; solubility, soluble in water; molecular weight, 160,000W180,000; chemical composition; total phosphorus, 0.1W0.15%; methyl pentose, 0.7W1.0%; total aminoacid, 70W80%; the precipitation reaction is agar gel, 1 prepciptation line to anti-M serum and serums separated into every antibody group and no line to antilipoteichoic serum, further characteristically high antiopsonization activity, immunogenecity and human complement activation. Then, a serum is collected from the animal to produce antiserum or antibody against group A hemolystic streptococci. When it is immunized by no use of adjuvant, high antibody value is obtained and the product is used as a vaccine of low toxicity.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9306181A JPS57209228A (en) | 1981-06-18 | 1981-06-18 | Hemolytic streptococcus m-protein |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9306181A JPS57209228A (en) | 1981-06-18 | 1981-06-18 | Hemolytic streptococcus m-protein |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57209228A true JPS57209228A (en) | 1982-12-22 |
Family
ID=14071993
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP9306181A Pending JPS57209228A (en) | 1981-06-18 | 1981-06-18 | Hemolytic streptococcus m-protein |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57209228A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0182240A2 (en) * | 1984-11-23 | 1986-05-28 | Miles Inc. | Preparation of enzyme-detergent extracted streptococcus equi vaccine |
-
1981
- 1981-06-18 JP JP9306181A patent/JPS57209228A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0182240A2 (en) * | 1984-11-23 | 1986-05-28 | Miles Inc. | Preparation of enzyme-detergent extracted streptococcus equi vaccine |
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