JPS57208987A - Lymph cell system capable of fusing at high fusing degree - Google Patents

Lymph cell system capable of fusing at high fusing degree

Info

Publication number
JPS57208987A
JPS57208987A JP57047507A JP4750782A JPS57208987A JP S57208987 A JPS57208987 A JP S57208987A JP 57047507 A JP57047507 A JP 57047507A JP 4750782 A JP4750782 A JP 4750782A JP S57208987 A JPS57208987 A JP S57208987A
Authority
JP
Japan
Prior art keywords
fusing
cell system
system capable
degree
lymph cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP57047507A
Other languages
Japanese (ja)
Inventor
Ruisu Rundaku Robaato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
University of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California filed Critical University of California
Publication of JPS57208987A publication Critical patent/JPS57208987A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/33—Insulin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1323—Adult fibroblasts
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/948—Microorganisms using viruses or cell lines
JP57047507A 1981-03-26 1982-03-26 Lymph cell system capable of fusing at high fusing degree Pending JPS57208987A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/247,656 US4594325A (en) 1981-03-26 1981-03-26 High fusion frequency fusible lymphoblastoid cell line

Publications (1)

Publication Number Publication Date
JPS57208987A true JPS57208987A (en) 1982-12-22

Family

ID=22935785

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57047507A Pending JPS57208987A (en) 1981-03-26 1982-03-26 Lymph cell system capable of fusing at high fusing degree

Country Status (3)

Country Link
US (1) US4594325A (en)
EP (1) EP0062409A3 (en)
JP (1) JPS57208987A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58205773A (en) * 1982-05-27 1983-11-30 Canon Inc Ink jet printer
JPS59132886A (en) * 1983-01-20 1984-07-31 Suntory Ltd Novel hybridoma
JPS606190A (en) * 1983-06-24 1985-01-12 Agency Of Ind Science & Technol Novel cell strain
JPS6012973A (en) * 1983-03-11 1985-01-23 スロ−ン−ケツタリング・インステイテユ−ト・フオ−・キヤンサ−・リサ−チ Single clone antibody of human from lymph of patient having malignant black tumor
JPS61104796A (en) * 1984-10-26 1986-05-23 Chemo Sero Therapeut Res Inst Preparation of monoclonal antibody

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1247538A (en) * 1982-05-21 1988-12-28 Mark C. Glassy Human-human hybridomas for solid tumors
US5057598A (en) * 1983-05-06 1991-10-15 Centocor, Inc. Monoclonal antibodies reactive with endotoxin core
NO841953L (en) * 1983-05-18 1984-11-19 Ortho Pharma Canada MUTANT HUMAN T-CELL LINE AND PROCEDURE FOR THEIR PREPARATION
US4897466A (en) * 1984-04-26 1990-01-30 Cetus Corporation Human lymphoblastoid cell line and hybridomas derived therefrom
US4624921A (en) * 1984-04-26 1986-11-25 Cetus Corporation Human lymphoblastold cell line and hybridomas derived therefrom
US4757018A (en) * 1985-02-11 1988-07-12 Hazleton Biotechnologies, Inc. Myeloma cell lines and uses thereof
US4720459A (en) * 1985-02-14 1988-01-19 Medical College Of Wisconsin Research Foundation, Inc. Myelomas for producing human/human hybridomas
US4677070A (en) * 1985-04-26 1987-06-30 Cetus Corporation Pseudomonas aeruginosa exotoxin A antibodies, their preparation and use
USH1198H (en) 1985-04-26 1993-06-01 Cetus Corporation Pseudomonas aeruginosa type-specific human monoclonal antibodies, their preparation and use
US5112738A (en) * 1985-07-03 1992-05-12 Miles Inc. Histamine derivatives, immunogen conjugates and antibodies raised thereto
US5001065A (en) * 1987-05-27 1991-03-19 Cetus Corporation Human cell line and triomas, antibodies, and transformants derived therefrom
US5215913A (en) 1987-11-30 1993-06-01 Roger Williams General Hospital IgG-1 human monoclonal antibody reactive with an HIV-1 antigen and methods of use
JPH0763363B2 (en) * 1991-12-25 1995-07-12 萩原 義秀 Method for obtaining fused cells
US6274552B1 (en) 1993-03-18 2001-08-14 Cytimmune Sciences, Inc. Composition and method for delivery of biologically-active factors
US20010055581A1 (en) * 1994-03-18 2001-12-27 Lawrence Tamarkin Composition and method for delivery of biologically-active factors
US7229841B2 (en) * 2001-04-30 2007-06-12 Cytimmune Sciences, Inc. Colloidal metal compositions and methods
US6407218B1 (en) * 1997-11-10 2002-06-18 Cytimmune Sciences, Inc. Method and compositions for enhancing immune response and for the production of in vitro mabs
JP2008504216A (en) * 2003-12-02 2008-02-14 サイトイミューン サイエンシズ インコーポレイテッド Methods and compositions for the production of monoclonal antibodies
US20050175584A1 (en) * 2004-01-28 2005-08-11 Paciotti Giulio F. Functionalized colloidal metal compositions and methods
US20110014118A1 (en) * 2007-09-21 2011-01-20 Lawrence Tamarkin Nanotherapeutic colloidal metal compositions and methods
KR20100123674A (en) * 2007-09-21 2010-11-24 싸이티뮨 사이언스, 인크. Nanotherapeutic colloidal metal compositions and methods
US7960145B2 (en) * 2007-11-08 2011-06-14 Cytimmune Sciences, Inc. Compositions and methods for generating antibodies
EP2349955B1 (en) * 2008-10-10 2016-03-30 Badger Licensing, LLC Process for producing alkylaromatic compounds

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58205773A (en) * 1982-05-27 1983-11-30 Canon Inc Ink jet printer
JPS59132886A (en) * 1983-01-20 1984-07-31 Suntory Ltd Novel hybridoma
JPS6012973A (en) * 1983-03-11 1985-01-23 スロ−ン−ケツタリング・インステイテユ−ト・フオ−・キヤンサ−・リサ−チ Single clone antibody of human from lymph of patient having malignant black tumor
JPS606190A (en) * 1983-06-24 1985-01-12 Agency Of Ind Science & Technol Novel cell strain
JPH0352956B2 (en) * 1983-06-24 1991-08-13 Kogyo Gijutsuin
JPS61104796A (en) * 1984-10-26 1986-05-23 Chemo Sero Therapeut Res Inst Preparation of monoclonal antibody

Also Published As

Publication number Publication date
EP0062409A2 (en) 1982-10-13
US4594325A (en) 1986-06-10
EP0062409A3 (en) 1982-11-24

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