JPS5718664A - N-substituted-bicyclo- 2.2.1 -hept-5-ene-2,3-dicarboximide derivative - Google Patents

N-substituted-bicyclo- 2.2.1 -hept-5-ene-2,3-dicarboximide derivative

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Publication number
JPS5718664A
JPS5718664A JP9369080A JP9369080A JPS5718664A JP S5718664 A JPS5718664 A JP S5718664A JP 9369080 A JP9369080 A JP 9369080A JP 9369080 A JP9369080 A JP 9369080A JP S5718664 A JPS5718664 A JP S5718664A
Authority
JP
Japan
Prior art keywords
hept
bicyclo
ene
bond
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP9369080A
Other languages
Japanese (ja)
Inventor
Naoto Ishibashi
Eiichi Suenaga
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MORISHITA SEIYAKU KK
Morishita Pharmaceuticals Co Ltd
Sanwa Kagaku Kenkyusho Co Ltd
Original Assignee
MORISHITA SEIYAKU KK
Morishita Pharmaceuticals Co Ltd
Sanwa Kagaku Kenkyusho Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MORISHITA SEIYAKU KK, Morishita Pharmaceuticals Co Ltd, Sanwa Kagaku Kenkyusho Co Ltd filed Critical MORISHITA SEIYAKU KK
Priority to JP9369080A priority Critical patent/JPS5718664A/en
Publication of JPS5718664A publication Critical patent/JPS5718664A/en
Pending legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

NEW MATERIAL:An N-substituted-bicyclo-[2.2.1]-hept-5-ene-2,3-dicarboximide derivative expressed by formula I (n is 4W6; the bond between the 5- and the 6- positions represents a double bond).
EXAMPLE: N-(1-Hydroxycyclopentylmethyl)-bicyclo-[2.2.1]-hept-5-ene-2,3-dicarboximide.
USE: A remedy for cholecystitis, cholangitis, cholecystolithiasis and bile duct dyskinesia having improved cholagogic action.
PROCESS: A bicyclo-[2.2.1]-hept-5-ene-2,3-dicarboxylic anhydride expressed by formula II is refluxed with 1-aminomethylcyclopentanol hydrochloride, etc. in the presence of an organic base, e.g. triethylamine, in an organic solvent for several hours under heating to give the compound expressed by formula I in which the bond between the 5- and the 6- positions is a double bond. The resultant compound is then reduced in the presence of a catalyst, e.g. Raney nickel, to afford the compound expressed by formula I in which the bond between the 5- and the 6- positions is a single bond.
COPYRIGHT: (C)1982,JPO&Japio
JP9369080A 1980-07-07 1980-07-07 N-substituted-bicyclo- 2.2.1 -hept-5-ene-2,3-dicarboximide derivative Pending JPS5718664A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP9369080A JPS5718664A (en) 1980-07-07 1980-07-07 N-substituted-bicyclo- 2.2.1 -hept-5-ene-2,3-dicarboximide derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9369080A JPS5718664A (en) 1980-07-07 1980-07-07 N-substituted-bicyclo- 2.2.1 -hept-5-ene-2,3-dicarboximide derivative

Publications (1)

Publication Number Publication Date
JPS5718664A true JPS5718664A (en) 1982-01-30

Family

ID=14089394

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9369080A Pending JPS5718664A (en) 1980-07-07 1980-07-07 N-substituted-bicyclo- 2.2.1 -hept-5-ene-2,3-dicarboximide derivative

Country Status (1)

Country Link
JP (1) JPS5718664A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4743805A (en) * 1985-09-09 1988-05-10 Kabushiki Kaisha Toshiba Anode assembly of magnetron and method of manufacturing the same

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4743805A (en) * 1985-09-09 1988-05-10 Kabushiki Kaisha Toshiba Anode assembly of magnetron and method of manufacturing the same

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