JPS57176945A - 4-phenoxy-3-hydroxybutylamidoxime derivative, manufacture and use - Google Patents

4-phenoxy-3-hydroxybutylamidoxime derivative, manufacture and use

Info

Publication number
JPS57176945A
JPS57176945A JP57054761A JP5476182A JPS57176945A JP S57176945 A JPS57176945 A JP S57176945A JP 57054761 A JP57054761 A JP 57054761A JP 5476182 A JP5476182 A JP 5476182A JP S57176945 A JPS57176945 A JP S57176945A
Authority
JP
Japan
Prior art keywords
phenoxy
hydroxybutylamidoxime
derivative
manufacture
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57054761A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6358820B2 (en:Method
Inventor
Rafuon Rui
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cephalon France SAS
Original Assignee
Laboratoire L Lafon SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire L Lafon SA filed Critical Laboratoire L Lafon SA
Publication of JPS57176945A publication Critical patent/JPS57176945A/ja
Publication of JPS6358820B2 publication Critical patent/JPS6358820B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
    • C07C259/14—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
JP57054761A 1981-03-31 1982-03-31 4-phenoxy-3-hydroxybutylamidoxime derivative, manufacture and use Granted JPS57176945A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8106469A FR2503147A1 (fr) 1981-03-31 1981-03-31 Derives de 4-phenoxy-3-hydroxy-butyramidoxine, leur procede de preparation et leur utilisation en therapeutique

Publications (2)

Publication Number Publication Date
JPS57176945A true JPS57176945A (en) 1982-10-30
JPS6358820B2 JPS6358820B2 (en:Method) 1988-11-17

Family

ID=9256834

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57054761A Granted JPS57176945A (en) 1981-03-31 1982-03-31 4-phenoxy-3-hydroxybutylamidoxime derivative, manufacture and use

Country Status (11)

Country Link
US (1) US4409242A (en:Method)
EP (1) EP0063508B1 (en:Method)
JP (1) JPS57176945A (en:Method)
AT (1) ATE7908T1 (en:Method)
CA (1) CA1177493A (en:Method)
DE (1) DE3260242D1 (en:Method)
DK (1) DK144082A (en:Method)
ES (1) ES510983A0 (en:Method)
FR (1) FR2503147A1 (en:Method)
GR (1) GR76039B (en:Method)
IE (1) IE52792B1 (en:Method)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS517662A (ja) * 1974-07-08 1976-01-22 Toshin Giken Kk Teiryokyokyusochi

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2210388A1 (en) * 1972-12-14 1974-07-12 Lafon Labor 4-Phenoxy-3-hydroxy-butyramidines - as agents for treating cardiac rhythm disorders

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS517662A (ja) * 1974-07-08 1976-01-22 Toshin Giken Kk Teiryokyokyusochi

Also Published As

Publication number Publication date
FR2503147A1 (fr) 1982-10-08
EP0063508A1 (fr) 1982-10-27
FR2503147B1 (en:Method) 1984-05-25
JPS6358820B2 (en:Method) 1988-11-17
IE52792B1 (en) 1988-03-02
GR76039B (en:Method) 1984-08-03
ES8303311A1 (es) 1983-02-01
US4409242A (en) 1983-10-11
ES510983A0 (es) 1983-02-01
CA1177493A (en) 1984-11-06
DE3260242D1 (en) 1984-07-19
IE820760L (en) 1982-09-30
EP0063508B1 (fr) 1984-06-13
ATE7908T1 (de) 1984-06-15
DK144082A (da) 1982-10-01

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