JPS57175124A - Antitumor drug - Google Patents

Antitumor drug

Info

Publication number
JPS57175124A
JPS57175124A JP56061653A JP6165381A JPS57175124A JP S57175124 A JPS57175124 A JP S57175124A JP 56061653 A JP56061653 A JP 56061653A JP 6165381 A JP6165381 A JP 6165381A JP S57175124 A JPS57175124 A JP S57175124A
Authority
JP
Japan
Prior art keywords
drug
microbial cell
antitumor
component
streptococcus faecalis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP56061653A
Other languages
Japanese (ja)
Inventor
Tsutomu Irikura
Eisuke Kojima
Satoru Murayama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyorin Pharmaceutical Co Ltd
Original Assignee
Kyorin Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Pharmaceutical Co Ltd filed Critical Kyorin Pharmaceutical Co Ltd
Priority to JP56061653A priority Critical patent/JPS57175124A/en
Publication of JPS57175124A publication Critical patent/JPS57175124A/en
Pending legal-status Critical Current

Links

Landscapes

  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

PURPOSE: To obtain an antitumor drug for an injection, internal use, suppository or application, by incorporating a microbial cell of a bacterium, belonging to Streptococcus faecalis, and capable of showing the antitumor effect, or a specific substance held in the interior or exterior of the microbial cell thereof in the agent.
CONSTITUTION: A bacterium, e.g. Streptococcus faecalis K-179 (FERM-P No. 5963) belonging to Streptococcus faecalis is cultivated, and the microbial cell obtained from the culture fluid by the centrifugation is washed. The microbial membrane is then broken by the physico-chemical treatment, and the solid content is removed by the centrifugation. The resultant component in the microbial cell is the dried and stored. The component is dissolved in a solvent in use to give an antitumor drug in the dosage form of an injection, drug for internal use, suppository or drug for application. Retinol or retinoic acid capable of increasing the adjuvant activity is used in a mixture with the component to improve the antitumor activity thereof.
COPYRIGHT: (C)1982,JPO&Japio
JP56061653A 1981-04-23 1981-04-23 Antitumor drug Pending JPS57175124A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP56061653A JPS57175124A (en) 1981-04-23 1981-04-23 Antitumor drug

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56061653A JPS57175124A (en) 1981-04-23 1981-04-23 Antitumor drug

Publications (1)

Publication Number Publication Date
JPS57175124A true JPS57175124A (en) 1982-10-28

Family

ID=13177393

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56061653A Pending JPS57175124A (en) 1981-04-23 1981-04-23 Antitumor drug

Country Status (1)

Country Link
JP (1) JPS57175124A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0228861A2 (en) * 1985-12-19 1987-07-15 Kabushiki Kaisya Advance Agent for reducing the dimethylnitrosoamine level

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0228861A2 (en) * 1985-12-19 1987-07-15 Kabushiki Kaisya Advance Agent for reducing the dimethylnitrosoamine level

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