JPS57139098A - Preparation of intermediate for preparing corticoid - Google Patents

Preparation of intermediate for preparing corticoid

Info

Publication number
JPS57139098A
JPS57139098A JP2530581A JP2530581A JPS57139098A JP S57139098 A JPS57139098 A JP S57139098A JP 2530581 A JP2530581 A JP 2530581A JP 2530581 A JP2530581 A JP 2530581A JP S57139098 A JPS57139098 A JP S57139098A
Authority
JP
Japan
Prior art keywords
dione
steroid
dihalogenated
diene
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2530581A
Other languages
Japanese (ja)
Inventor
Kazumasa Nitta
Shinichiro Fujimori
Toshio Haruyama
Shinya Inoue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Kasei Corp
Original Assignee
Mitsubishi Kasei Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Kasei Corp filed Critical Mitsubishi Kasei Corp
Priority to JP2530581A priority Critical patent/JPS57139098A/en
Publication of JPS57139098A publication Critical patent/JPS57139098A/en
Pending legal-status Critical Current

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  • Steroid Compounds (AREA)

Abstract

PURPOSE: To obtain the titled intermediate for preparing adrenocortical hormones in short steps, by bringing a novel dihalogenated steroid obtained from androsta-4,9(11)-diene-3,17-dione, etc. into contact with a metallic powder, e.g. zinc or iron.
CONSTITUTION: A novel dihalogenated steroid, e.g. 17α-dihydroxy-21,21-dibromopregna-1,4-diene-3,20-dione 17-acetate, of formulaI(the dotted line is single or double bond; X is halogen; Y is acyloxy) obtained from androsta-4,9(11)-diene- 3,17-dione easily derived from 9α-hydroxyandrost-4-ene-3,17-dione as a raw material is brought into contact with a metallic powder, e.g. zinc or iron, in a molar amount of preferably 5W20 times that of the dihalogenated steroid to give the aimed pregnane steroid of formula II.
USE: Useful as a leuteohormone itself.
COPYRIGHT: (C)1982,JPO&Japio
JP2530581A 1981-02-23 1981-02-23 Preparation of intermediate for preparing corticoid Pending JPS57139098A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2530581A JPS57139098A (en) 1981-02-23 1981-02-23 Preparation of intermediate for preparing corticoid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2530581A JPS57139098A (en) 1981-02-23 1981-02-23 Preparation of intermediate for preparing corticoid

Publications (1)

Publication Number Publication Date
JPS57139098A true JPS57139098A (en) 1982-08-27

Family

ID=12162297

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2530581A Pending JPS57139098A (en) 1981-02-23 1981-02-23 Preparation of intermediate for preparing corticoid

Country Status (1)

Country Link
JP (1) JPS57139098A (en)

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