JPS57139098A - Preparation of intermediate for preparing corticoid - Google Patents
Preparation of intermediate for preparing corticoidInfo
- Publication number
- JPS57139098A JPS57139098A JP2530581A JP2530581A JPS57139098A JP S57139098 A JPS57139098 A JP S57139098A JP 2530581 A JP2530581 A JP 2530581A JP 2530581 A JP2530581 A JP 2530581A JP S57139098 A JPS57139098 A JP S57139098A
- Authority
- JP
- Japan
- Prior art keywords
- dione
- steroid
- dihalogenated
- diene
- preparing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Steroid Compounds (AREA)
Abstract
PURPOSE: To obtain the titled intermediate for preparing adrenocortical hormones in short steps, by bringing a novel dihalogenated steroid obtained from androsta-4,9(11)-diene-3,17-dione, etc. into contact with a metallic powder, e.g. zinc or iron.
CONSTITUTION: A novel dihalogenated steroid, e.g. 17α-dihydroxy-21,21-dibromopregna-1,4-diene-3,20-dione 17-acetate, of formulaI(the dotted line is single or double bond; X is halogen; Y is acyloxy) obtained from androsta-4,9(11)-diene- 3,17-dione easily derived from 9α-hydroxyandrost-4-ene-3,17-dione as a raw material is brought into contact with a metallic powder, e.g. zinc or iron, in a molar amount of preferably 5W20 times that of the dihalogenated steroid to give the aimed pregnane steroid of formula II.
USE: Useful as a leuteohormone itself.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2530581A JPS57139098A (en) | 1981-02-23 | 1981-02-23 | Preparation of intermediate for preparing corticoid |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2530581A JPS57139098A (en) | 1981-02-23 | 1981-02-23 | Preparation of intermediate for preparing corticoid |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57139098A true JPS57139098A (en) | 1982-08-27 |
Family
ID=12162297
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2530581A Pending JPS57139098A (en) | 1981-02-23 | 1981-02-23 | Preparation of intermediate for preparing corticoid |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57139098A (en) |
-
1981
- 1981-02-23 JP JP2530581A patent/JPS57139098A/en active Pending
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Jeffcoate et al. | Preparation of a specific antiserum to estradiol-17β coupled to protein through the B-ring | |
GB1494097A (en) | D-homo-20-keto-pregnanes | |
JPH0469639B2 (en) | ||
KR890700130A (en) | Method for Steroidal 17α-silyl ether and corticosteroids and progesterone | |
JPS5798300A (en) | Manufacture of pregnane derivative | |
GB1291205A (en) | A novel pregnane derivative, processes for its preparation, and compositions incorporating it | |
JPS57139098A (en) | Preparation of intermediate for preparing corticoid | |
JPS52136157A (en) | Preparation of steroid 17-esters | |
JPS57139099A (en) | Preparation of intermediate for preparing corticoid | |
JPS5210489A (en) | Preparation of 17-esters of pregnane steroids | |
GB1037891A (en) | Process for the manufacture of 19-nor-steroids | |
US3347880A (en) | 17alpha-halogenoethinylestranes | |
GB1232745A (en) | ||
JPS51149258A (en) | A process for preparing steroid derivatives | |
EP0402963A3 (en) | 17-alpha ethynyl steroids | |
JPS6471899A (en) | Steroid compound | |
AU529292B2 (en) | 17-substituted pregnane steroids | |
JPS54119446A (en) | Preparation of estrone | |
YU26779A (en) | Process for preparing anti-inflammatory steroids the androstane series | |
JPS52144663A (en) | Preparation of pregnane steroid 17alpha-ester 21-halides | |
JPS56120698A (en) | Steroid and its preparation | |
US3591582A (en) | Process for preparing alpha-acyloxy ketone steroids | |
IE36260L (en) | Steroidal silyl ethers | |
US3437657A (en) | 6-fluoromethyl-3-oxo-4,6-dienic steroids and process for preparing same | |
US3467713A (en) | Process for the defluorination of fluorosteroids |