JPS57112325A - Aggregation inhibitor of blood platelet - Google Patents
Aggregation inhibitor of blood plateletInfo
- Publication number
- JPS57112325A JPS57112325A JP55179169A JP17916980A JPS57112325A JP S57112325 A JPS57112325 A JP S57112325A JP 55179169 A JP55179169 A JP 55179169A JP 17916980 A JP17916980 A JP 17916980A JP S57112325 A JPS57112325 A JP S57112325A
- Authority
- JP
- Japan
- Prior art keywords
- aggregation
- blood platelets
- protopine
- inhibitor
- blood
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
PURPOSE: An aggregation inhibitor of blood platelets, containing protopine or a salt thereof, useful as a preventing agent and remedy for cerebromalacia, cardiac infarction, etc., and having powerful aggregation inhibitory action on the blood platelets.
CONSTITUTION: An aggregation inhibitor of blood platelets containing protopine or a salt thereof extracted and purified from a constituent of a plant belonging to the family Papaveraceae. The protopine has aggregation inhibitory action on blood platelets about 10 times that of the aspirin, and inhibits the aggregation in an amount of 250W500μg/ml remarkably and dissociates the aggregation almost completely. The improvement in local circulation of blood by the action renders the inhibitor useful as a preventing agent and remedy for subconjunctival hemorrhage and remits the tension of ciliary muscles and congestion in a nipple. Another effect, e.g. prevention or treatment of short sight, is expectable. The oral dose is generally 1W500mg/day usually divided in several fractions. As for an injection, the dose is 0.1W100mg/day in one W divided fractions, and as for an external agent such as an eye drop, the concentration of 50W1,000μg/ml is applicable.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55179169A JPS57112325A (en) | 1980-12-17 | 1980-12-17 | Aggregation inhibitor of blood platelet |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55179169A JPS57112325A (en) | 1980-12-17 | 1980-12-17 | Aggregation inhibitor of blood platelet |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57112325A true JPS57112325A (en) | 1982-07-13 |
JPS634804B2 JPS634804B2 (en) | 1988-02-01 |
Family
ID=16061139
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP55179169A Granted JPS57112325A (en) | 1980-12-17 | 1980-12-17 | Aggregation inhibitor of blood platelet |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57112325A (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0218703U (en) * | 1988-07-22 | 1990-02-07 | ||
US10711238B2 (en) | 2012-10-02 | 2020-07-14 | Repligen Corporation | Method for proliferation of cells within a bioreactor using a disposable pumphead and filter assembly |
-
1980
- 1980-12-17 JP JP55179169A patent/JPS57112325A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS634804B2 (en) | 1988-02-01 |
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