JPS57102895A - Organogermanium compound - Google Patents
Organogermanium compoundInfo
- Publication number
- JPS57102895A JPS57102895A JP55178075A JP17807580A JPS57102895A JP S57102895 A JPS57102895 A JP S57102895A JP 55178075 A JP55178075 A JP 55178075A JP 17807580 A JP17807580 A JP 17807580A JP S57102895 A JPS57102895 A JP S57102895A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- organogermanium compound
- organogermanium
- trichlorogermylpropionitrile
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 Organogermanium compound Chemical class 0.000 title abstract 2
- VXZCIDLVEYVOOX-UHFFFAOYSA-N 3-trichlorogermylpropanenitrile Chemical compound Cl[Ge](Cl)(Cl)CCC#N VXZCIDLVEYVOOX-UHFFFAOYSA-N 0.000 abstract 1
- NLHHRLWOUZZQLW-UHFFFAOYSA-N Acrylonitrile Chemical compound C=CC#N NLHHRLWOUZZQLW-UHFFFAOYSA-N 0.000 abstract 1
- 241001529936 Murinae Species 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 238000007259 addition reaction Methods 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- MUDDKLJPADVVKF-UHFFFAOYSA-N trichlorogermane Chemical compound Cl[GeH](Cl)Cl MUDDKLJPADVVKF-UHFFFAOYSA-N 0.000 abstract 1
Abstract
NEW MATERIAL:An organogermanium compound of the formula (A and B are H or lower alkyl; n is an integer ≥2).
USE: An antitumor agent capable of exhibiting a powerful antitumor activity against murine solid cancers.
PROCESS: Trichlorogermane is subjected to the addition reaction with acrylonitrile, and the resultant β-trichlorogermylpropionitrile is hydrolyzed in a relatively low concentration for a long time to give the compound of the formula (A and B are H).
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55178075A JPS57102895A (en) | 1980-12-18 | 1980-12-18 | Organogermanium compound |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55178075A JPS57102895A (en) | 1980-12-18 | 1980-12-18 | Organogermanium compound |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57102895A true JPS57102895A (en) | 1982-06-26 |
JPH0341492B2 JPH0341492B2 (en) | 1991-06-24 |
Family
ID=16042175
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP55178075A Granted JPS57102895A (en) | 1980-12-18 | 1980-12-18 | Organogermanium compound |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57102895A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57145887A (en) * | 1981-11-16 | 1982-09-09 | Ryuichi Sato | Organic germanium polymer |
JPS57145888A (en) * | 1981-11-16 | 1982-09-09 | Ryuichi Sato | Organic germanium polymer |
US4973553A (en) * | 1987-09-09 | 1990-11-27 | Asai Germanium Research Institute | Salt or organogermanium compound and medicine containing the same |
WO2021080019A1 (en) | 2019-10-24 | 2021-04-29 | 株式会社浅井ゲルマニウム研究所 | Novel organogermanium compound |
-
1980
- 1980-12-18 JP JP55178075A patent/JPS57102895A/en active Granted
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57145887A (en) * | 1981-11-16 | 1982-09-09 | Ryuichi Sato | Organic germanium polymer |
JPS57145888A (en) * | 1981-11-16 | 1982-09-09 | Ryuichi Sato | Organic germanium polymer |
JPS5936998B2 (en) * | 1981-11-16 | 1984-09-06 | 隆一 佐藤 | organic germanium polymer |
US4973553A (en) * | 1987-09-09 | 1990-11-27 | Asai Germanium Research Institute | Salt or organogermanium compound and medicine containing the same |
WO2021080019A1 (en) | 2019-10-24 | 2021-04-29 | 株式会社浅井ゲルマニウム研究所 | Novel organogermanium compound |
Also Published As
Publication number | Publication date |
---|---|
JPH0341492B2 (en) | 1991-06-24 |
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