JPS5692241A - 1-aroyl-3-halogenocyclohexene - Google Patents
1-aroyl-3-halogenocyclohexeneInfo
- Publication number
- JPS5692241A JPS5692241A JP16814979A JP16814979A JPS5692241A JP S5692241 A JPS5692241 A JP S5692241A JP 16814979 A JP16814979 A JP 16814979A JP 16814979 A JP16814979 A JP 16814979A JP S5692241 A JPS5692241 A JP S5692241A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- halogenocyclohexene
- aroyl
- ketoprofen
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:A 1-aroyl-3-halogenocyclohexene of formula I (Ar is aryl; X is halogen).
EXAMPLE: 3-Bromo-1-benzoylcyclohexene.
USE: A raw material of ketoprofen having excellent analgesic and antiphlogistic activities. Ketoprofen can be prepared from the compound in short steps.
PROCESS: The compound of formula I is prepared by halogenating, e.g. 1-aroylcyclohexene of formula II with a halogenating agent such as N-bromosuccinimide, pref. under light irradiation, or in the presence of a radical-generating agent such as benzoyl peroxide.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16814979A JPS5692241A (en) | 1979-12-26 | 1979-12-26 | 1-aroyl-3-halogenocyclohexene |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16814979A JPS5692241A (en) | 1979-12-26 | 1979-12-26 | 1-aroyl-3-halogenocyclohexene |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5692241A true JPS5692241A (en) | 1981-07-25 |
Family
ID=15862723
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP16814979A Pending JPS5692241A (en) | 1979-12-26 | 1979-12-26 | 1-aroyl-3-halogenocyclohexene |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5692241A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH11322645A (en) * | 1998-05-15 | 1999-11-24 | Asahi Chem Ind Co Ltd | Chlorination of cycloalkene |
-
1979
- 1979-12-26 JP JP16814979A patent/JPS5692241A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH11322645A (en) * | 1998-05-15 | 1999-11-24 | Asahi Chem Ind Co Ltd | Chlorination of cycloalkene |
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