JPS5686200A - Adenine nucleoside and its preparation - Google Patents

Adenine nucleoside and its preparation

Info

Publication number
JPS5686200A
JPS5686200A JP16279879A JP16279879A JPS5686200A JP S5686200 A JPS5686200 A JP S5686200A JP 16279879 A JP16279879 A JP 16279879A JP 16279879 A JP16279879 A JP 16279879A JP S5686200 A JPS5686200 A JP S5686200A
Authority
JP
Japan
Prior art keywords
adenine
azido
formula
arabinofuranosyl
dideoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP16279879A
Other languages
Japanese (ja)
Inventor
Kazuo Fujiyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamasa Shoyu KK
Original Assignee
Yamasa Shoyu KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamasa Shoyu KK filed Critical Yamasa Shoyu KK
Priority to JP16279879A priority Critical patent/JPS5686200A/en
Publication of JPS5686200A publication Critical patent/JPS5686200A/en
Pending legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Saccharide Compounds (AREA)

Abstract

NEW MATERIAL:An adenine nucleoside expressed by formula I [R1 is azido or amino; R2 and R3 are H or protecting group (e.g. aralkyl such as trityl or benzyl, or acyl such as acetyl or benzoyl)].
EXAMPLE: 9-(2-Azido-2,3-dideoxy-β-D-arabinofuranosyl)adenine.
USE: An agent for biochemical research or a synthetic intermediate for physiologically active substances such as 5'-phosphate derivatives thereof which have an inhibitory action on a nucleic acid synthesizing enzyme.
PROCESS: A 2'-0-alkylsulfonyl or allylsulfonylcordycepin of formula II (R4 is alkylsulfonyl or allylsulfonyl) is reacted with an alkali azide, preferably in a solvent, e.g. pyridine, at about 100°C for several hour to give a 9-(2-azido-2,3-dideoxy-β-D-arabinofuranosyl)adenine of formula III.
COPYRIGHT: (C)1981,JPO&Japio
JP16279879A 1979-12-17 1979-12-17 Adenine nucleoside and its preparation Pending JPS5686200A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16279879A JPS5686200A (en) 1979-12-17 1979-12-17 Adenine nucleoside and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16279879A JPS5686200A (en) 1979-12-17 1979-12-17 Adenine nucleoside and its preparation

Publications (1)

Publication Number Publication Date
JPS5686200A true JPS5686200A (en) 1981-07-13

Family

ID=15761403

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16279879A Pending JPS5686200A (en) 1979-12-17 1979-12-17 Adenine nucleoside and its preparation

Country Status (1)

Country Link
JP (1) JPS5686200A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0287313A2 (en) * 1987-04-17 1988-10-19 THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce Acid stable dideoxynucleosides active against the cytopathic effects of human immunodeficiency virus
JPH07116212B1 (en) * 1987-04-23 1995-12-13

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0287313A2 (en) * 1987-04-17 1988-10-19 THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce Acid stable dideoxynucleosides active against the cytopathic effects of human immunodeficiency virus
JPH07116212B1 (en) * 1987-04-23 1995-12-13

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