JPS5678055A - Liquid chromatograph mass spectrograph - Google Patents

Liquid chromatograph mass spectrograph

Info

Publication number
JPS5678055A
JPS5678055A JP15510579A JP15510579A JPS5678055A JP S5678055 A JPS5678055 A JP S5678055A JP 15510579 A JP15510579 A JP 15510579A JP 15510579 A JP15510579 A JP 15510579A JP S5678055 A JPS5678055 A JP S5678055A
Authority
JP
Japan
Prior art keywords
effluent
liquid chromatograph
sample
leading pipe
nozzle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP15510579A
Other languages
Japanese (ja)
Inventor
Etsuo Yamauchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jeol Ltd
Original Assignee
Jeol Ltd
Nihon Denshi KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jeol Ltd, Nihon Denshi KK filed Critical Jeol Ltd
Priority to JP15510579A priority Critical patent/JPS5678055A/en
Publication of JPS5678055A publication Critical patent/JPS5678055A/en
Pending legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0431—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
    • H01J49/0445—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples with means for introducing as a spray, a jet or an aerosol
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • G01N30/724—Nebulising, aerosol formation or ionisation
    • G01N30/7246—Nebulising, aerosol formation or ionisation by pneumatic means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • G01N30/7273—Desolvation chambers
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0468—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components with means for heating or cooling the sample
    • H01J49/049—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components with means for heating or cooling the sample with means for applying heat to desorb the sample; Evaporation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)

Abstract

PURPOSE:To vaporize the effluent continuously by leading the effluent from a liquid chromatograph to a vacuum chamber, atomizing with a jet stream of an atomizing gas, heating and vaporizing, and sending to an ion source. CONSTITUTION:A sample 2 is analyzed with a liquid chromatograph 1, the detected output is recorded in a recorder 7, and a part of the effluent from the detector 6 is flown from a splitter 8 to a sample leading pipe 14. The effluent passing through the sample leading pipe 14 is cooled with a low temperature fluid 15 and lead to a vacuum chamber 11. At the end of the sample leading pipe 14, a high speed jet stream of an atomizing gas of not less than several 10 Torr which is flowing from a nozzle 12 to a nozzle 13 is formed, where the effluent is atomized to form fine mist. Fine mist thus obtained is vaporized with heat of a heater 16, and sent to an ion source 9 to ionize.
JP15510579A 1979-11-30 1979-11-30 Liquid chromatograph mass spectrograph Pending JPS5678055A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP15510579A JPS5678055A (en) 1979-11-30 1979-11-30 Liquid chromatograph mass spectrograph

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15510579A JPS5678055A (en) 1979-11-30 1979-11-30 Liquid chromatograph mass spectrograph

Publications (1)

Publication Number Publication Date
JPS5678055A true JPS5678055A (en) 1981-06-26

Family

ID=15598715

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15510579A Pending JPS5678055A (en) 1979-11-30 1979-11-30 Liquid chromatograph mass spectrograph

Country Status (1)

Country Link
JP (1) JPS5678055A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4808819A (en) * 1987-02-03 1989-02-28 Hitachi, Ltd. Mass spectrometric apparatus
US4864187A (en) * 1985-05-25 1989-09-05 Mitsubishi Denki Kabushiki Kaisha Cathode for electron tube and manufacturing method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4864187A (en) * 1985-05-25 1989-09-05 Mitsubishi Denki Kabushiki Kaisha Cathode for electron tube and manufacturing method thereof
US4808819A (en) * 1987-02-03 1989-02-28 Hitachi, Ltd. Mass spectrometric apparatus

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