JPS5657712A - Carcinostatic agent - Google Patents
Carcinostatic agentInfo
- Publication number
- JPS5657712A JPS5657712A JP13339279A JP13339279A JPS5657712A JP S5657712 A JPS5657712 A JP S5657712A JP 13339279 A JP13339279 A JP 13339279A JP 13339279 A JP13339279 A JP 13339279A JP S5657712 A JPS5657712 A JP S5657712A
- Authority
- JP
- Japan
- Prior art keywords
- cancerous cell
- dihydroxybenzaldoxime
- pax
- day
- agent containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PURPOSE: To provide a benzaldehyde-type carcinostatic agent containing 3,4-dihydroxybenzaldoxime as an effective component.
CONSTITUTION: An agent containing 3,4-dihydroxybenzaldoxime (procatechualdehyde: abbr. PAX) as an effective component. Similar to 3,4-dihydroxybenzaldehyde which has been found by the inventors, the compound causes the selective dissapearance of the fission image of human cancerous cell, and the enlargement of the cancerous cell and nucleus compared with normal human cell. The phenomena prove the selective DNA synthesis inhibiting action of the compound to the cancerous cell. The effective dose of PAX is pref. 0.1W30mg/kg/day for oral administration and 0.1W20mg/kg/day for parenteral administration.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13339279A JPS5657712A (en) | 1979-10-15 | 1979-10-15 | Carcinostatic agent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13339279A JPS5657712A (en) | 1979-10-15 | 1979-10-15 | Carcinostatic agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5657712A true JPS5657712A (en) | 1981-05-20 |
Family
ID=15103665
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP13339279A Pending JPS5657712A (en) | 1979-10-15 | 1979-10-15 | Carcinostatic agent |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5657712A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001043712A1 (en) * | 1999-12-14 | 2001-06-21 | Haarmann & Reimer Gmbh | Catechol oximes and their use in cosmetic and dermatological preparations |
| US6693126B2 (en) * | 2000-10-27 | 2004-02-17 | Choongwae Pharm. Co., Ltd. | Dihydroxyphenyl derivatives for hepatoprotection and treatment of liver diseases |
| KR100919624B1 (en) * | 2007-09-11 | 2009-09-30 | 경북대학교 산학협력단 | Composition for prevention and treatment for leukemia comprising 3,4-dihydroxybenzaldehyde extracted from Xanthium strumarium |
| CN110693862A (en) * | 2019-11-02 | 2020-01-17 | 上海中医药大学附属岳阳中西医结合医院 | Application of protocatechualdehyde in inhibiting CtBP1 |
-
1979
- 1979-10-15 JP JP13339279A patent/JPS5657712A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001043712A1 (en) * | 1999-12-14 | 2001-06-21 | Haarmann & Reimer Gmbh | Catechol oximes and their use in cosmetic and dermatological preparations |
| US6693126B2 (en) * | 2000-10-27 | 2004-02-17 | Choongwae Pharm. Co., Ltd. | Dihydroxyphenyl derivatives for hepatoprotection and treatment of liver diseases |
| KR100919624B1 (en) * | 2007-09-11 | 2009-09-30 | 경북대학교 산학협력단 | Composition for prevention and treatment for leukemia comprising 3,4-dihydroxybenzaldehyde extracted from Xanthium strumarium |
| CN110693862A (en) * | 2019-11-02 | 2020-01-17 | 上海中医药大学附属岳阳中西医结合医院 | Application of protocatechualdehyde in inhibiting CtBP1 |
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