JPS5655357A - Manufacture of diphenylethers - Google Patents
Manufacture of diphenylethersInfo
- Publication number
- JPS5655357A JPS5655357A JP13143780A JP13143780A JPS5655357A JP S5655357 A JPS5655357 A JP S5655357A JP 13143780 A JP13143780 A JP 13143780A JP 13143780 A JP13143780 A JP 13143780A JP S5655357 A JPS5655357 A JP S5655357A
- Authority
- JP
- Japan
- Prior art keywords
- carbon atoms
- alkyl
- phenoxy
- hydrogen
- halogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
- C07C201/06—Preparation of nitro compounds
- C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/04—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reaction of ammonia or amines with olefin oxides or halohydrins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C241/00—Preparation of compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
- C07C241/02—Preparation of hydrazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
Abstract
The method of preparing a compound of the formula <IMAGE> wherein R1 is hydrogen, halogen, alkyl of 1 to 8 carbon atoms, trifluoromethyl or acetyl; n is 1 when R1 has all the defined meanings, or 2 or 3 when R1 is halogen or alkyl; R2 is hydrogen; alkyl of 1 to 16 carbon atoms; alkenyl of 2 to 16 carbon atoms; alkinyl of 2 to 16 carbon atoms; monosubstituted alkyl of 2 to 6 carbon atoms, where the substituent is hydroxyl, alkoxy of 1 to 4 carbon atoms, phenoxy, halo-phenoxy, (alkyl of 1 to 4 carbon atoms) phenoxy, (alkoxy of 1 to 4 carbon atoms)phenoxy, nitro-phenoxy, cyano-phenoxy, amino or (alkyl of 1 to 4 carbon atoms)thio; benzyl; halo-benzyl; -NR3R4; -CHR3-COOR4; or -CHR3-CONR4R5, where R3, R4 and R5 are each hydrogen or alkyl of 1 to 8 carbon atoms; and X1 and X2 are each hydrogen or halogen, which comprises reacting a compound of the formula <IMAGE> wherein n, R1, X1 and X2 have the meanings previously defined, and R1 is unsubstituted or substituted phenyl, with an amine of the formula H2N-R2 wherein R2 has the meanings previously defined, at a temperature between about 20 DEG and 160 DEG C.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19792938595 DE2938595A1 (en) | 1979-09-24 | 1979-09-24 | METHOD FOR PRODUCING DIPHENYL ETHERS |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5655357A true JPS5655357A (en) | 1981-05-15 |
JPH0259135B2 JPH0259135B2 (en) | 1990-12-11 |
Family
ID=6081697
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP13143780A Granted JPS5655357A (en) | 1979-09-24 | 1980-09-19 | Manufacture of diphenylethers |
Country Status (18)
Country | Link |
---|---|
US (1) | US4364875A (en) |
EP (1) | EP0027555B1 (en) |
JP (1) | JPS5655357A (en) |
AT (1) | ATE5773T1 (en) |
AU (1) | AU529324B2 (en) |
BR (1) | BR8006061A (en) |
CA (1) | CA1181088A (en) |
DD (1) | DD154697A5 (en) |
DE (2) | DE2938595A1 (en) |
DK (1) | DK164045C (en) |
ES (1) | ES8201519A1 (en) |
HU (1) | HU182205B (en) |
IE (1) | IE50314B1 (en) |
IL (1) | IL61118A (en) |
MA (1) | MA18956A1 (en) |
NZ (1) | NZ195025A (en) |
YU (1) | YU42355B (en) |
ZA (1) | ZA805885B (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58170736A (en) * | 1982-03-18 | 1983-10-07 | シエル・インターナシヨネイル・リサーチ・マーチヤツピイ・ベー・ウイ | Manufacture of diphenylethers |
JP2016534134A (en) * | 2013-09-09 | 2016-11-04 | ペロトン セラピューティクス, インコーポレイテッド | Aryl ethers and uses thereof |
US10786480B2 (en) | 2015-04-17 | 2020-09-29 | Peloton Therapeutics, Inc. | Combination therapy of a HIF-2-α inhibitor and an immunotherapeutic agent and uses thereof |
US10807948B2 (en) | 2015-03-11 | 2020-10-20 | Peloton Therapeutics, Inc. | Aromatic compounds and uses thereof |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3269621D1 (en) * | 1981-08-07 | 1986-04-10 | Ciba Geigy Ag | Phenoxyphenyl-aminocarboxylic-acid derivatives, their preparation, compositions containing them and their use |
US4913729A (en) * | 1981-10-19 | 1990-04-03 | Rohm And Haas Company | Herbicidal 4-trifluoromethyl-3'-substituted amine-4'-nitro diphenyl ethers |
EP0080746B1 (en) * | 1981-11-09 | 1985-08-21 | Duphar International Research B.V | New diphenyl ethers having herbicidal activity |
US4526608A (en) * | 1982-07-14 | 1985-07-02 | Zoecon Corporation | Certain 2-pyridyloxyphenyl-oximino-ether-carboxylates, herbicidal compositions containing same and their herbicidal method of use |
DE3300585A1 (en) * | 1983-01-11 | 1984-07-12 | Basf Ag, 6700 Ludwigshafen | DIPHENYL ETHER, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR CONTROLLING UNWANTED PLANT GROWTH |
US4694105A (en) * | 1983-12-20 | 1987-09-15 | Ciba-Geigy Corporation | Herbicidal alkoxyamino- and polyalkoxyaminodiphenyl ethers |
US5024691A (en) * | 1985-02-25 | 1991-06-18 | Ici Americas Inc. | Substituted phenoxy benzamide herbicides and methods of use |
GB8520774D0 (en) * | 1985-08-20 | 1985-09-25 | Shell Int Research | Diphenyl ether herbicides |
JP2655359B2 (en) * | 1990-01-25 | 1997-09-17 | 富士写真フイルム株式会社 | Synthesis of aromatic amines, aromatic alcohols and aromatic thiols by aromatic nucleophilic substitution reaction |
US5424280A (en) * | 1993-10-07 | 1995-06-13 | American Cyanamid Company | Aryloxybenzene herbicidal agents |
CN103242178A (en) * | 2013-05-09 | 2013-08-14 | 北京颖泰嘉和生物科技有限公司 | Synthetic method of 2-chloro-3-phenoxyl-6-nitroaniline |
US10155726B2 (en) | 2015-03-11 | 2018-12-18 | Peloton Therapeutics, Inc. | Substituted pyridines and uses thereof |
WO2016145045A1 (en) | 2015-03-11 | 2016-09-15 | Peloton Therapeutics, Inc. | Compositions for use in treating glioblastoma |
WO2016145032A1 (en) | 2015-03-11 | 2016-09-15 | Peloton Therapeutics, Inc. | Compositions for use in treating pulmonary arterial hypertension |
US11104754B2 (en) * | 2016-11-15 | 2021-08-31 | Evonik Operations Gmbh | Asymmetrically substituted bis-alkenyl diphenyl ethers, their preparation and use |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS49236A (en) * | 1972-03-14 | 1974-01-05 | ||
JPS51138633A (en) * | 1975-05-13 | 1976-11-30 | Ciba Geigy Ag | Process for preparing diaryl compound |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3914310A (en) * | 1965-08-06 | 1975-10-21 | Ciba Geigy Corp | Phenoxy-substituted ortho-nitroanilines and ortho-phenylenediamines |
CH462847A (en) * | 1965-11-11 | 1968-09-30 | Agripat Sa | Process for the production of halogenated nitroanilines |
US4039588A (en) * | 1969-05-28 | 1977-08-02 | Rohm And Haas Company | Herbicidal 4-nitro-diphenyl ethers |
US3920445A (en) * | 1970-02-28 | 1975-11-18 | Bayer Ag | Substituted 6-nitroaniline compounds and herbicidal compositions |
US3798276A (en) * | 1972-03-14 | 1974-03-19 | H Bayer | Herbicidal 4-trifluoromethyl-4'-nitrodiphenyl ethers |
US4046798A (en) * | 1973-02-12 | 1977-09-06 | Rohm And Haas Company | Herbicidal 4-trifluoromethyl-4'nitrodiphenyl ethers |
JPS525486B2 (en) * | 1973-02-13 | 1977-02-14 | ||
CH599752A5 (en) * | 1973-04-18 | 1978-05-31 | Ciba Geigy Ag | |
LU76304A1 (en) * | 1976-12-01 | 1978-07-10 | ||
DE2800105A1 (en) * | 1977-01-11 | 1978-07-13 | Ciba Geigy Ag | USE OF DIPHENYLAETHERS AS ALGICIDES |
DE2831262A1 (en) * | 1978-07-15 | 1980-01-31 | Celamerck Gmbh & Co Kg | 2-CHLORINE-6-NITROANILINE |
-
1979
- 1979-09-24 DE DE19792938595 patent/DE2938595A1/en not_active Withdrawn
-
1980
- 1980-09-19 JP JP13143780A patent/JPS5655357A/en active Granted
- 1980-09-20 AT AT80105658T patent/ATE5773T1/en active
- 1980-09-20 EP EP80105658A patent/EP0027555B1/en not_active Expired
- 1980-09-20 DE DE8080105658T patent/DE3066058D1/en not_active Expired
- 1980-09-22 HU HU802316A patent/HU182205B/en unknown
- 1980-09-22 MA MA19157A patent/MA18956A1/en unknown
- 1980-09-22 DD DD80224048A patent/DD154697A5/en not_active IP Right Cessation
- 1980-09-23 AU AU62642/80A patent/AU529324B2/en not_active Expired
- 1980-09-23 ZA ZA00805885A patent/ZA805885B/en unknown
- 1980-09-23 IL IL61118A patent/IL61118A/en not_active IP Right Cessation
- 1980-09-23 NZ NZ195025A patent/NZ195025A/en unknown
- 1980-09-23 IE IE1982/80A patent/IE50314B1/en not_active IP Right Cessation
- 1980-09-23 ES ES495249A patent/ES8201519A1/en not_active Expired
- 1980-09-23 BR BR8006061A patent/BR8006061A/en unknown
- 1980-09-23 DK DK402280A patent/DK164045C/en not_active IP Right Cessation
- 1980-09-24 YU YU2432/80A patent/YU42355B/en unknown
- 1980-09-24 CA CA000360960A patent/CA1181088A/en not_active Expired
-
1981
- 1981-07-07 US US06/281,123 patent/US4364875A/en not_active Expired - Lifetime
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS49236A (en) * | 1972-03-14 | 1974-01-05 | ||
JPS51138633A (en) * | 1975-05-13 | 1976-11-30 | Ciba Geigy Ag | Process for preparing diaryl compound |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58170736A (en) * | 1982-03-18 | 1983-10-07 | シエル・インターナシヨネイル・リサーチ・マーチヤツピイ・ベー・ウイ | Manufacture of diphenylethers |
JP2016534134A (en) * | 2013-09-09 | 2016-11-04 | ペロトン セラピューティクス, インコーポレイテッド | Aryl ethers and uses thereof |
US10597366B2 (en) | 2013-09-09 | 2020-03-24 | Peloton Therapeutics, Inc. | Aryl ethers and uses thereof |
US10807948B2 (en) | 2015-03-11 | 2020-10-20 | Peloton Therapeutics, Inc. | Aromatic compounds and uses thereof |
US10786480B2 (en) | 2015-04-17 | 2020-09-29 | Peloton Therapeutics, Inc. | Combination therapy of a HIF-2-α inhibitor and an immunotherapeutic agent and uses thereof |
Also Published As
Publication number | Publication date |
---|---|
IL61118A0 (en) | 1980-11-30 |
AU6264280A (en) | 1982-04-01 |
DK164045C (en) | 1992-09-28 |
ATE5773T1 (en) | 1984-01-15 |
DK402280A (en) | 1981-03-25 |
HU182205B (en) | 1983-12-28 |
DE2938595A1 (en) | 1981-04-23 |
YU42355B (en) | 1988-08-31 |
YU243280A (en) | 1983-02-28 |
CA1181088A (en) | 1985-01-15 |
EP0027555A1 (en) | 1981-04-29 |
DD154697A5 (en) | 1982-04-14 |
ES495249A0 (en) | 1981-11-16 |
ES8201519A1 (en) | 1981-11-16 |
MA18956A1 (en) | 1981-04-01 |
ZA805885B (en) | 1982-05-26 |
EP0027555B1 (en) | 1984-01-04 |
BR8006061A (en) | 1981-04-07 |
IE50314B1 (en) | 1986-04-02 |
IE801982L (en) | 1981-03-24 |
AU529324B2 (en) | 1983-06-02 |
US4364875A (en) | 1982-12-21 |
DE3066058D1 (en) | 1984-02-09 |
NZ195025A (en) | 1983-05-31 |
IL61118A (en) | 1984-07-31 |
DK164045B (en) | 1992-05-04 |
JPH0259135B2 (en) | 1990-12-11 |
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