JPS5651493A - Diphosphoglycerol and its preparation - Google Patents
Diphosphoglycerol and its preparationInfo
- Publication number
- JPS5651493A JPS5651493A JP12750479A JP12750479A JPS5651493A JP S5651493 A JPS5651493 A JP S5651493A JP 12750479 A JP12750479 A JP 12750479A JP 12750479 A JP12750479 A JP 12750479A JP S5651493 A JPS5651493 A JP S5651493A
- Authority
- JP
- Japan
- Prior art keywords
- salt
- formula
- organic amine
- improving
- barium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Abstract
NEW MATERIAL:1,2-Diphosphogylcerol of the formula and a salt thereof.
USE: Having the action to enhance the oxygen supply ability to the tissue and useful for improving the activity of the heart, improving hypoxia and ischemic diseases and prolonging the life of erythrocyte after the blood transfusion.
PROCESS: 2,3-Bis(diphenylphosphoryl)glycerol-1-phenyl ether is reduced (subjected to hydrogenolysis) in the presence of a platinum catalyst, e.g. platinum oxide, in a solvent, e.g. ethanol, methanol or acetic acid, at 20W70°C, preferably 20W 30°C, to give the titled compound of the formula, which is then treated with barium hydroxide or an organic amine ro afford a barium salt or organic amine salt in the form of crystalline power. The salt can be converted into another suitable salt, e.g. lithium, sodium, potassium or cyclohexylamine salt, by treating the salt with an ion exchange resin.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12750479A JPS5651493A (en) | 1979-10-02 | 1979-10-02 | Diphosphoglycerol and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12750479A JPS5651493A (en) | 1979-10-02 | 1979-10-02 | Diphosphoglycerol and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5651493A true JPS5651493A (en) | 1981-05-09 |
Family
ID=14961610
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP12750479A Pending JPS5651493A (en) | 1979-10-02 | 1979-10-02 | Diphosphoglycerol and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5651493A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6228420U (en) * | 1985-07-31 | 1987-02-20 | ||
US9827335B2 (en) | 2009-10-30 | 2017-11-28 | General Electric Company | Treating water insoluble nanoparticles with hydrophilic alpha-hydroxyphosphonic acid conjugates, the so modified nanoparticles and their use as contrast agents |
-
1979
- 1979-10-02 JP JP12750479A patent/JPS5651493A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6228420U (en) * | 1985-07-31 | 1987-02-20 | ||
US9827335B2 (en) | 2009-10-30 | 2017-11-28 | General Electric Company | Treating water insoluble nanoparticles with hydrophilic alpha-hydroxyphosphonic acid conjugates, the so modified nanoparticles and their use as contrast agents |
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