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Mochida Pharmaceutical Co Ltd
Original Assignee
Mochida Pharmaceutical Co Ltd
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Application filed by Mochida Pharmaceutical Co LtdfiledCriticalMochida Pharmaceutical Co Ltd
Priority to JP12494379ApriorityCriticalpatent/JPS5649320A/en
Publication of JPS5649320ApublicationCriticalpatent/JPS5649320A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
PURPOSE: The titled remedy, useful for hypertension and heart failure and comprising 2,2'-iminodiquinoline as a main constituent.
CONSTITUTION: A remedy comprising 2,2'-iminodiquinoline or a salt thereof as a main constituent. The compound is obtained by heating 2-methylsulfonylquinoline with sodium amide in benzene. The remedy has a vasodilator, and a hypotensive actions and an inhibitory action on platelet coagulation, and is effective for a model of experimental angina pectoris with very low acute toxicity. Therefore, the remedy is effective against hypertension, heart failure, peripheral circulatory insufficiency and ischemic heart diseases for clinical use.
COPYRIGHT: (C)1981,JPO&Japio
JP12494379A1979-09-281979-09-28Remedy for cardiovascular disease
PendingJPS5649320A
(en)
NEW DERIVATIVES OF 3-AMINO-2-AZETIDINON-1 - ((2-HALO-ACETIL OR 2-HALOETILIDEN)) - ACETIC, PROCEDURE TO PREPARE THEM AND PROCEDURE TO OBTAIN 3-CEFEM COMPOUNDS FROM SUCH DERIVATIVES
PROCEDURE FOR THE OBTAINING OF NEW DERIVATIVES 5-HALOGEN-6- (2 ', 4'-DIHALOFENOXI) -1 (O 3)-SUBSTITUTED-2H-1,3-DIHIDROBENZIMIDAZOLE-2-TIONA, OR SIMILAR