JPS5642575B2 - - Google Patents
Info
- Publication number
- JPS5642575B2 JPS5642575B2 JP4859375A JP4859375A JPS5642575B2 JP S5642575 B2 JPS5642575 B2 JP S5642575B2 JP 4859375 A JP4859375 A JP 4859375A JP 4859375 A JP4859375 A JP 4859375A JP S5642575 B2 JPS5642575 B2 JP S5642575B2
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
- C07C45/58—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in three-membered rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
- C07C45/59—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/16—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/48—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP50048593A JPS51127041A (en) | 1975-04-23 | 1975-04-23 | A process for preparing novel 2-( substituted phenyl) alkane acids and their salts. |
| GB15149/76A GB1510042A (en) | 1975-04-23 | 1976-04-13 | Alkanoic acids and process for preparing the same |
| US05/677,092 US4092350A (en) | 1975-04-23 | 1976-04-14 | Alkanoic acid, process for its production and method of use thereof |
| FR7611706A FR2308358A1 (fr) | 1975-04-23 | 1976-04-21 | Nouvel acide ((oxo- ou hydroxy-3-alcoyl)-4-phenyl)-2-alcanoique et sel non toxique de celui-ci, procede de production de cet acide, composition pharmaceutique contenant un tel compose et methode pour traiter les symptomes d'inflammation et douleur |
| DE2617592A DE2617592C3 (de) | 1975-04-23 | 1976-04-22 | 2- [4-(3-Oxo- oder Hydroxy-alkyD-phenyl] -alkansäuren und deren nicht toxische Salze, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP50048593A JPS51127041A (en) | 1975-04-23 | 1975-04-23 | A process for preparing novel 2-( substituted phenyl) alkane acids and their salts. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS51127041A JPS51127041A (en) | 1976-11-05 |
| JPS5642575B2 true JPS5642575B2 (en:Method) | 1981-10-06 |
Family
ID=12807693
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50048593A Granted JPS51127041A (en) | 1975-04-23 | 1975-04-23 | A process for preparing novel 2-( substituted phenyl) alkane acids and their salts. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4092350A (en:Method) |
| JP (1) | JPS51127041A (en:Method) |
| DE (1) | DE2617592C3 (en:Method) |
| FR (1) | FR2308358A1 (en:Method) |
| GB (1) | GB1510042A (en:Method) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH669523A5 (en:Method) * | 1986-06-25 | 1989-03-31 | Mepha Ag | |
| US5179124A (en) * | 1988-01-25 | 1993-01-12 | University Of Iowa Research Foundation | Anti-inflammatory for use in external and internal eye inflammations |
| JP5770621B2 (ja) * | 2011-12-27 | 2015-08-26 | 株式会社Ｌｔｔバイオファーマ | ２−フルオロフェニルプロピオン酸誘導体 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3054779A (en) * | 1959-03-24 | 1962-09-18 | Dow Chemical Co | Para hydroxy alkyl aromatic carboxylic acids and polymers thereof |
| US3452079A (en) * | 1964-06-15 | 1969-06-24 | Merck & Co Inc | Acetic acid type compounds |
| US3457300A (en) * | 1965-06-11 | 1969-07-22 | Merck & Co Inc | Acetic acid type compounds |
| US3880916A (en) * | 1969-09-17 | 1975-04-29 | Ciba Geigy Corp | Cycloaliphatic acids |
| JPS5037183B2 (en:Method) * | 1973-01-29 | 1975-12-01 | ||
| US3888920A (en) * | 1973-08-06 | 1975-06-10 | Sandoz Ag | Aryl substituted-4-alkenoic acids |
-
1975
- 1975-04-23 JP JP50048593A patent/JPS51127041A/ja active Granted
-
1976
- 1976-04-13 GB GB15149/76A patent/GB1510042A/en not_active Expired
- 1976-04-14 US US05/677,092 patent/US4092350A/en not_active Expired - Lifetime
- 1976-04-21 FR FR7611706A patent/FR2308358A1/fr active Granted
- 1976-04-22 DE DE2617592A patent/DE2617592C3/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US4092350A (en) | 1978-05-30 |
| DE2617592C3 (de) | 1978-07-20 |
| FR2308358A1 (fr) | 1976-11-19 |
| DE2617592B2 (de) | 1977-12-01 |
| JPS51127041A (en) | 1976-11-05 |
| GB1510042A (en) | 1978-05-10 |
| FR2308358B1 (en:Method) | 1979-06-29 |
| DE2617592A1 (de) | 1976-11-11 |