JPS5630981A - Codeine 7,8-oxide and its acyl derivative - Google Patents
Codeine 7,8-oxide and its acyl derivativeInfo
- Publication number
- JPS5630981A JPS5630981A JP10781679A JP10781679A JPS5630981A JP S5630981 A JPS5630981 A JP S5630981A JP 10781679 A JP10781679 A JP 10781679A JP 10781679 A JP10781679 A JP 10781679A JP S5630981 A JPS5630981 A JP S5630981A
- Authority
- JP
- Japan
- Prior art keywords
- oxide
- codeine
- formula
- acyl derivative
- compound shown
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A codeine 7,8-oxide shown by the formula I (R is H or acyl) and its acyl derivative.
EXAMPLE: Codeine 7,8-oxide.
USE: A drug with action, e.g., painkilling, antitussive, and sedative action, etc.
PROCESS: Codeine 7,8-oxide is reduced with a metallic hydride, preferably sodium boron hydride, etc. under mild conditions to give codeine 7,8-oxide shown by the formula III, which is a compound shown by the formula I wherein R is H. The compound shown by the formula III is acylated to give 6-acylcodeine 7,8-oxide. The compound shown by the formula II, for example, is obtained by oxidizing codeinone with hydrogenperoxide.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10781679A JPS5630981A (en) | 1979-08-24 | 1979-08-24 | Codeine 7,8-oxide and its acyl derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10781679A JPS5630981A (en) | 1979-08-24 | 1979-08-24 | Codeine 7,8-oxide and its acyl derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5630981A true JPS5630981A (en) | 1981-03-28 |
JPS6145992B2 JPS6145992B2 (en) | 1986-10-11 |
Family
ID=14468753
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10781679A Granted JPS5630981A (en) | 1979-08-24 | 1979-08-24 | Codeine 7,8-oxide and its acyl derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5630981A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60198943A (en) * | 1984-03-22 | 1985-10-08 | Nec Corp | Network controller for terminal device |
-
1979
- 1979-08-24 JP JP10781679A patent/JPS5630981A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60198943A (en) * | 1984-03-22 | 1985-10-08 | Nec Corp | Network controller for terminal device |
Also Published As
Publication number | Publication date |
---|---|
JPS6145992B2 (en) | 1986-10-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
YU42983B (en) | Process for producing naphtiridinic derivatives | |
GB2044799B (en) | Ethanol production process | |
GB2094706B (en) | Feeding parisons to blow-mould | |
JPS55138294A (en) | Method of forming through hole connector | |
GB2059989B (en) | Ethanol production process | |
PH20768A (en) | New diazabicyclo-(3.3.1)-nonanes and a process for the preparation thereof | |
JPS55144095A (en) | Production of solid fuel for small furnace | |
GB2048267B (en) | Process for producing ethanol | |
GB2004256B (en) | Process for the production of uo2/puo2 nuclear fuels | |
GB2233259B (en) | Process for the manufacture of an armoured wall consisting of multi-layer steeland application to armour-plating. | |
GB2002361B (en) | Process for the production of 1,2,4-triazin-5-one derivatives | |
DE3066836D1 (en) | Improved process for the preparation of vinylcyclopropane derivatives | |
ZA802108B (en) | Means for the production of beer | |
DE3263567D1 (en) | New compounds with antiinflammatory and antitussive activity, process for their preparation and relative pharmaceutical compositions | |
ZA805385B (en) | Process for the production of fuel alcohol, without vinasse | |
JPS53145294A (en) | Method of increasing more double bottom of tanker | |
PH22005A (en) | Process for the preparation of new hemoserine derivatives | |
JPS5630981A (en) | Codeine 7,8-oxide and its acyl derivative | |
GB2046262B (en) | Process for the production of an acetal | |
GB2059960B (en) | Method for producing penicillanic acid derivatives | |
YU45480A (en) | Process for producing 2,2-dimethyl-1,2-dimethyl-1,2-dihydroquinoline derivatives used as antioxidats | |
JPS53114870A (en) | Production of double walled container | |
JPS53148539A (en) | Antiallergic agnet | |
DE3160133D1 (en) | 7,8-amino, hydroxy-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepines, process for their preparation and pharmaceutical compositions containing them | |
JPS54105101A (en) | Igniting agent for solid fuel |