JPS5630968A - Novel tricyclic cage-shaped amine derivative - Google Patents
Novel tricyclic cage-shaped amine derivativeInfo
- Publication number
- JPS5630968A JPS5630968A JP10747279A JP10747279A JPS5630968A JP S5630968 A JPS5630968 A JP S5630968A JP 10747279 A JP10747279 A JP 10747279A JP 10747279 A JP10747279 A JP 10747279A JP S5630968 A JPS5630968 A JP S5630968A
- Authority
- JP
- Japan
- Prior art keywords
- amine derivative
- lactone
- iodo
- give
- subjected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:Compounds of the formula (A1 is single bond or lower alkylene linking to the 2 or 3 position; A2 is lower alkylene; A3 is single bond or lower alkylene; R1 is H, lower alkyl, lower alkenyl, lower alkynyl; R2 is H, lower alkyl, lower alkenyl) and their acid salts.
EXAMPLE: Drug and its intermediate: they show remarkable controlling effect on influenza virus or herpes-simplex virus.
PROCESS: For example, the Diels-Alder reaction of a diene such as cyclopentadiene with a dienophil is effected and the adduct is subjected to crosslinking reaction to give a carboxylic acid. The carboxylic acid is subjected to iodo-lactonization to give an iodo-lactone, of which the iodine group is eliminated by reduction to form a lactone, which is led to an amino derivative, thus producing the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10747279A JPS5630968A (en) | 1979-08-22 | 1979-08-22 | Novel tricyclic cage-shaped amine derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10747279A JPS5630968A (en) | 1979-08-22 | 1979-08-22 | Novel tricyclic cage-shaped amine derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5630968A true JPS5630968A (en) | 1981-03-28 |
Family
ID=14460058
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10747279A Pending JPS5630968A (en) | 1979-08-22 | 1979-08-22 | Novel tricyclic cage-shaped amine derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5630968A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62232223A (en) * | 1986-03-25 | 1987-10-12 | シーメンス・テレコムニカツイオーニ・ソチエタ・ペル・アチオニ | Method and apparatus for equalizing adaptable blind |
-
1979
- 1979-08-22 JP JP10747279A patent/JPS5630968A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62232223A (en) * | 1986-03-25 | 1987-10-12 | シーメンス・テレコムニカツイオーニ・ソチエタ・ペル・アチオニ | Method and apparatus for equalizing adaptable blind |
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