JPS5624664B2 - - Google Patents
Info
- Publication number
- JPS5624664B2 JPS5624664B2 JP7340573A JP7340573A JPS5624664B2 JP S5624664 B2 JPS5624664 B2 JP S5624664B2 JP 7340573 A JP7340573 A JP 7340573A JP 7340573 A JP7340573 A JP 7340573A JP S5624664 B2 JPS5624664 B2 JP S5624664B2
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/16—Nitrogen-containing compounds
- C08K5/20—Carboxylic acid amides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Polyethers (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Paper (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7340573A JPS5624664B2 (enExample) | 1973-06-28 | 1973-06-28 | |
| IT2444874A IT1015418B (it) | 1973-06-28 | 1974-06-25 | Composti organici e procedimento per la loro preparazione |
| DE19742430998 DE2430998A1 (de) | 1973-06-28 | 1974-06-27 | Neue organische verbindungen mit einer n,n-dialkylsubstibuierten amidgruppe und verfahren zu deren herstellung |
| NL7408784A NL7408784A (enExample) | 1973-06-28 | 1974-06-28 | |
| FR7422691A FR2235112A1 (en) | 1973-06-28 | 1974-06-28 | Cpds contg dialkyl-substd amide gps - used as surfactants, dispersants, solvents, chelating agents and polymer modifiers |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7340573A JPS5624664B2 (enExample) | 1973-06-28 | 1973-06-28 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5024216A JPS5024216A (enExample) | 1975-03-15 |
| JPS5624664B2 true JPS5624664B2 (enExample) | 1981-06-08 |
Family
ID=13517239
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP7340573A Expired JPS5624664B2 (enExample) | 1973-06-28 | 1973-06-28 |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS5624664B2 (enExample) |
| DE (1) | DE2430998A1 (enExample) |
| FR (1) | FR2235112A1 (enExample) |
| IT (1) | IT1015418B (enExample) |
| NL (1) | NL7408784A (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5524563A (en) * | 1978-08-09 | 1980-02-21 | Nitto Electric Ind Co Ltd | Tubular membrane separating module |
| JP5777846B2 (ja) * | 2005-06-15 | 2015-09-09 | マサチューセッツ インスティテュート オブ テクノロジー | アミン含有脂質およびその使用 |
| CA3006395C (en) | 2008-11-07 | 2022-05-31 | Massachusetts Institute Of Technology | Aminoalcohol lipidoids and uses thereof |
| AU2010326132B9 (en) | 2009-12-01 | 2014-10-02 | Translate Bio, Inc. | Delivery of mRNA for the augmentation of proteins and enzymes in human genetic diseases |
| PL2691443T3 (pl) | 2011-03-28 | 2021-08-30 | Massachusetts Institute Of Technology | Sprzężone lipomery i ich zastosowania |
| EP4043025A1 (en) | 2011-06-08 | 2022-08-17 | Translate Bio, Inc. | Lipid nanoparticle compositions and methods for mrna delivery |
| EP3536787A1 (en) | 2012-06-08 | 2019-09-11 | Translate Bio, Inc. | Nuclease resistant polynucleotides and uses thereof |
| CA2884870C (en) | 2012-08-13 | 2022-03-29 | Massachusetts Institute Of Technology | Amine-containing lipidoids and uses thereof |
| LT2968586T (lt) | 2013-03-14 | 2018-11-26 | Translate Bio, Inc. | Cft mrnr kompozicijos bei su jomis susiję būdai ir panaudojimai |
| TR201901310T4 (tr) | 2013-03-14 | 2019-02-21 | Translate Bio Inc | Mesajcı RNA'nın saflaştırılması yöntemleri. |
| US9315472B2 (en) | 2013-05-01 | 2016-04-19 | Massachusetts Institute Of Technology | 1,3,5-triazinane-2,4,6-trione derivatives and uses thereof |
| JP6506749B2 (ja) | 2013-10-22 | 2019-04-24 | シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド | フェニルケトン尿症のためのｍＲＮＡ療法 |
| ES2865699T3 (es) | 2013-10-22 | 2021-10-15 | Translate Bio Inc | Formulaciones de lípidos para la administración de ARN mensajero |
| JP6608815B2 (ja) | 2013-10-22 | 2019-11-20 | トランスレイト バイオ， インコーポレイテッド | アルギニノコハク酸合成酵素欠損症のｍＲＮＡ治療 |
| CN106164248B (zh) | 2014-04-25 | 2019-10-15 | 川斯勒佰尔公司 | 信使rna的纯化方法 |
| MA48050A (fr) | 2014-05-30 | 2020-02-12 | Translate Bio Inc | Lipides biodégradables pour l'administration d'acides nucléiques |
| CN116059170A (zh) | 2014-06-24 | 2023-05-05 | 川斯勒佰尔公司 | 用于递送核酸的立体化学富集组合物 |
| US9840479B2 (en) | 2014-07-02 | 2017-12-12 | Massachusetts Institute Of Technology | Polyamine-fatty acid derived lipidoids and uses thereof |
| AU2018224326B2 (en) | 2017-02-27 | 2024-01-04 | Translate Bio, Inc. | Novel codon-optimized CFTR mRNA |
| CA3063531A1 (en) | 2017-05-16 | 2018-11-22 | Translate Bio, Inc. | Treatment of cystic fibrosis by delivery of codon-optimized mrna encoding cftr |
| CA3108544A1 (en) | 2018-08-24 | 2020-02-27 | Translate Bio, Inc. | Methods for purification of messenger rna |
| AU2019384557B2 (en) | 2018-11-21 | 2025-07-17 | Translate Bio, Inc. | Treatment of cystic fibrosis by delivery of nebulized mRNA encoding CFTR |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2372808A (en) * | 1941-07-30 | 1945-04-03 | Resinous Prod & Chemical Co | Esters of poly-beta-carboxyalkyl ethers of polyhydric alcohols |
-
1973
- 1973-06-28 JP JP7340573A patent/JPS5624664B2/ja not_active Expired
-
1974
- 1974-06-25 IT IT2444874A patent/IT1015418B/it active
- 1974-06-27 DE DE19742430998 patent/DE2430998A1/de active Pending
- 1974-06-28 NL NL7408784A patent/NL7408784A/xx unknown
- 1974-06-28 FR FR7422691A patent/FR2235112A1/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| DE2430998A1 (de) | 1975-01-09 |
| JPS5024216A (enExample) | 1975-03-15 |
| FR2235112A1 (en) | 1975-01-24 |
| IT1015418B (it) | 1977-05-10 |
| NL7408784A (enExample) | 1974-12-31 |