JPS5624664B2 - - Google Patents
Info
- Publication number
- JPS5624664B2 JPS5624664B2 JP7340573A JP7340573A JPS5624664B2 JP S5624664 B2 JPS5624664 B2 JP S5624664B2 JP 7340573 A JP7340573 A JP 7340573A JP 7340573 A JP7340573 A JP 7340573A JP S5624664 B2 JPS5624664 B2 JP S5624664B2
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/16—Nitrogen-containing compounds
- C08K5/20—Carboxylic acid amides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Polyethers (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Paper (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7340573A JPS5624664B2 (cg-RX-API-DMAC7.html) | 1973-06-28 | 1973-06-28 | |
| IT2444874A IT1015418B (it) | 1973-06-28 | 1974-06-25 | Composti organici e procedimento per la loro preparazione |
| DE19742430998 DE2430998A1 (de) | 1973-06-28 | 1974-06-27 | Neue organische verbindungen mit einer n,n-dialkylsubstibuierten amidgruppe und verfahren zu deren herstellung |
| NL7408784A NL7408784A (cg-RX-API-DMAC7.html) | 1973-06-28 | 1974-06-28 | |
| FR7422691A FR2235112A1 (en) | 1973-06-28 | 1974-06-28 | Cpds contg dialkyl-substd amide gps - used as surfactants, dispersants, solvents, chelating agents and polymer modifiers |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7340573A JPS5624664B2 (cg-RX-API-DMAC7.html) | 1973-06-28 | 1973-06-28 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5024216A JPS5024216A (cg-RX-API-DMAC7.html) | 1975-03-15 |
| JPS5624664B2 true JPS5624664B2 (cg-RX-API-DMAC7.html) | 1981-06-08 |
Family
ID=13517239
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP7340573A Expired JPS5624664B2 (cg-RX-API-DMAC7.html) | 1973-06-28 | 1973-06-28 |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS5624664B2 (cg-RX-API-DMAC7.html) |
| DE (1) | DE2430998A1 (cg-RX-API-DMAC7.html) |
| FR (1) | FR2235112A1 (cg-RX-API-DMAC7.html) |
| IT (1) | IT1015418B (cg-RX-API-DMAC7.html) |
| NL (1) | NL7408784A (cg-RX-API-DMAC7.html) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5524563A (en) * | 1978-08-09 | 1980-02-21 | Nitto Electric Ind Co Ltd | Tubular membrane separating module |
| EP2476756A1 (en) * | 2005-06-15 | 2012-07-18 | Massachusetts Institute of Technology | Amine-containing lipids and uses thereof |
| CN104910025B (zh) | 2008-11-07 | 2019-07-16 | 麻省理工学院 | 氨基醇类脂质和其用途 |
| EP3318248B1 (en) | 2009-12-01 | 2019-04-10 | Translate Bio, Inc. | Delivery of mrna for the augmentation of proteins and enzymes in human genetic diseases |
| CA2831392C (en) | 2011-03-28 | 2020-04-28 | Massachusetts Institute Of Technology | Conjugated lipomers and uses thereof |
| EP2717893B1 (en) | 2011-06-08 | 2019-05-08 | Translate Bio, Inc. | Lipid nanoparticle compositions and methods for mrna delivery |
| WO2013185067A1 (en) | 2012-06-08 | 2013-12-12 | Shire Human Genetic Therapies, Inc. | Nuclease resistant polynucleotides and uses thereof |
| CA2884870C (en) | 2012-08-13 | 2022-03-29 | Massachusetts Institute Of Technology | Amine-containing lipidoids and uses thereof |
| LT2968586T (lt) | 2013-03-14 | 2018-11-26 | Translate Bio, Inc. | Cft mrnr kompozicijos bei su jomis susiję būdai ir panaudojimai |
| TR201901310T4 (tr) | 2013-03-14 | 2019-02-21 | Translate Bio Inc | Mesajcı RNA'nın saflaştırılması yöntemleri. |
| US9315472B2 (en) | 2013-05-01 | 2016-04-19 | Massachusetts Institute Of Technology | 1,3,5-triazinane-2,4,6-trione derivatives and uses thereof |
| EP3574923A1 (en) | 2013-10-22 | 2019-12-04 | Translate Bio, Inc. | Mrna therapy for phenylketonuria |
| CN112618732A (zh) | 2013-10-22 | 2021-04-09 | 夏尔人类遗传性治疗公司 | 用于递送信使rna的脂质制剂 |
| BR112016009014B1 (pt) | 2013-10-22 | 2024-02-06 | Translate Bio, Inc | USO DE COMPOSIÇÃO COMPREENDENDO mRNA PARA DEFICIÊNCIA DE ARGININOSSUCINATO SINTETASE |
| KR102739894B1 (ko) | 2014-04-25 | 2024-12-05 | 샤이어 휴먼 지네틱 테라피즈 인크. | 메신저 rna 의 정제 방법 |
| US10022455B2 (en) | 2014-05-30 | 2018-07-17 | Translate Bio, Inc. | Biodegradable lipids for delivery of nucleic acids |
| CN111588695A (zh) | 2014-06-24 | 2020-08-28 | 川斯勒佰尔公司 | 用于递送核酸的立体化学富集组合物 |
| WO2016004202A1 (en) | 2014-07-02 | 2016-01-07 | Massachusetts Institute Of Technology | Polyamine-fatty acid derived lipidoids and uses thereof |
| EP3585417B1 (en) | 2017-02-27 | 2023-02-22 | Translate Bio, Inc. | Method of making a codon-optimized cftr mrna |
| CA3063531A1 (en) | 2017-05-16 | 2018-11-22 | Translate Bio, Inc. | Treatment of cystic fibrosis by delivery of codon-optimized mrna encoding cftr |
| CA3108544A1 (en) | 2018-08-24 | 2020-02-27 | Translate Bio, Inc. | Methods for purification of messenger rna |
| CA3120647A1 (en) | 2018-11-21 | 2020-05-28 | Translate Bio, Inc. | Treatment of cystic fibrosis by delivery of nebulized mrna encoding cftr |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2372808A (en) * | 1941-07-30 | 1945-04-03 | Resinous Prod & Chemical Co | Esters of poly-beta-carboxyalkyl ethers of polyhydric alcohols |
-
1973
- 1973-06-28 JP JP7340573A patent/JPS5624664B2/ja not_active Expired
-
1974
- 1974-06-25 IT IT2444874A patent/IT1015418B/it active
- 1974-06-27 DE DE19742430998 patent/DE2430998A1/de active Pending
- 1974-06-28 FR FR7422691A patent/FR2235112A1/fr not_active Withdrawn
- 1974-06-28 NL NL7408784A patent/NL7408784A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL7408784A (cg-RX-API-DMAC7.html) | 1974-12-31 |
| FR2235112A1 (en) | 1975-01-24 |
| DE2430998A1 (de) | 1975-01-09 |
| IT1015418B (it) | 1977-05-10 |
| JPS5024216A (cg-RX-API-DMAC7.html) | 1975-03-15 |