JPS5622724A - Pharmaceutical preparation of n4-acylcytosine arabinoside - Google Patents

Pharmaceutical preparation of n4-acylcytosine arabinoside

Info

Publication number
JPS5622724A
JPS5622724A JP9807579A JP9807579A JPS5622724A JP S5622724 A JPS5622724 A JP S5622724A JP 9807579 A JP9807579 A JP 9807579A JP 9807579 A JP9807579 A JP 9807579A JP S5622724 A JPS5622724 A JP S5622724A
Authority
JP
Japan
Prior art keywords
arabinoside
acylcytosine
liposome
lecithin
stearylamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP9807579A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5715087B2 (enExample
Inventor
Yoshio Sakurai
Takeyuki Kataoka
Fujiko Ohashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Chemical Industry Co Ltd
Original Assignee
Asahi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Chemical Industry Co Ltd filed Critical Asahi Chemical Industry Co Ltd
Priority to JP9807579A priority Critical patent/JPS5622724A/ja
Priority to US06/169,422 priority patent/US4330534A/en
Priority to GB8024259A priority patent/GB2055578B/en
Priority to FR8016995A priority patent/FR2468365A1/fr
Publication of JPS5622724A publication Critical patent/JPS5622724A/ja
Publication of JPS5715087B2 publication Critical patent/JPS5715087B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP9807579A 1979-08-02 1979-08-02 Pharmaceutical preparation of n4-acylcytosine arabinoside Granted JPS5622724A (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP9807579A JPS5622724A (en) 1979-08-02 1979-08-02 Pharmaceutical preparation of n4-acylcytosine arabinoside
US06/169,422 US4330534A (en) 1979-08-02 1980-07-16 N4 -Acylcytosine arabinoside compositions
GB8024259A GB2055578B (en) 1979-08-02 1980-07-24 N4-acylcytosine arabinoside preparation
FR8016995A FR2468365A1 (fr) 1979-08-02 1980-07-31 Preparations de n4-acylcytosine arabinoside et composition pharmaceutique les contenant

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9807579A JPS5622724A (en) 1979-08-02 1979-08-02 Pharmaceutical preparation of n4-acylcytosine arabinoside

Publications (2)

Publication Number Publication Date
JPS5622724A true JPS5622724A (en) 1981-03-03
JPS5715087B2 JPS5715087B2 (enExample) 1982-03-29

Family

ID=14210221

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9807579A Granted JPS5622724A (en) 1979-08-02 1979-08-02 Pharmaceutical preparation of n4-acylcytosine arabinoside

Country Status (4)

Country Link
US (1) US4330534A (enExample)
JP (1) JPS5622724A (enExample)
FR (1) FR2468365A1 (enExample)
GB (1) GB2055578B (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5888027U (ja) * 1981-12-09 1983-06-15 厚木自動車部品株式会社 カ−ク−ラ用電磁クラツチの制御装置
JPS6416727A (en) * 1987-07-10 1989-01-20 Asahi Chemical Ind Novel medical preparation of ara-c derivative
JPH01113319A (ja) * 1987-10-27 1989-05-02 Nippon Oil & Fats Co Ltd リポソームカプセル化したマクロファージ活性化剤
JPH03115737A (ja) * 1989-09-29 1991-05-16 Mitsubishi Heavy Ind Ltd 可変マツチング機構を有する過給機システム

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4684630A (en) * 1983-08-24 1987-08-04 Repta Arnold J Method of parenterally delivering drugs and related compositions
US4663167A (en) * 1984-04-16 1987-05-05 The Board Of Regents Of The University Of Texas System Composition and method for treatment of disseminated fungal infections in mammals
US4978654A (en) * 1984-04-16 1990-12-18 Board Of Regents, The University Of Texas System Composition and method for treatment of disseminated fungal infections in mammals
US5117022A (en) * 1985-10-18 1992-05-26 The Board Of Regents, The University Of Texas System Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
US5384127A (en) * 1985-10-18 1995-01-24 Board Of Regents, The University Of Texas System Stable liposomal formulations of lipophilic platinum compounds
US5041581A (en) * 1985-10-18 1991-08-20 The University Of Texas System Board Of Regents Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
US4812312A (en) * 1987-03-03 1989-03-14 Board Of Regents Of The University Of Texas System Liposome-incorporated nystatin
US5811119A (en) * 1987-05-19 1998-09-22 Board Of Regents, The University Of Texas Formulation and use of carotenoids in treatment of cancer
US5690954A (en) * 1987-05-22 1997-11-25 Danbiosyst Uk Limited Enhanced uptake drug delivery system having microspheres containing an active drug and a bioavailability improving material
GB8723846D0 (en) * 1987-10-10 1987-11-11 Danbiosyst Ltd Bioadhesive microsphere drug delivery system
US4981690A (en) * 1987-10-27 1991-01-01 Board Of Regents, The University Of Texas System Liposome-incorporated mepartricin
US4946683A (en) * 1987-11-18 1990-08-07 Vestar, Inc. Multiple step entrapment/loading procedure for preparing lipophilic drug-containing liposomes
AU608415B2 (en) * 1988-01-19 1991-03-28 University Of Texas System, The Esters of 3'-deaminodoxorubicin, liposomal compositions thereof
US20040208922A1 (en) * 1995-06-07 2004-10-21 The Regents Of The University Of California Method for loading lipid like vesicles with drugs or other chemicals
WO2000048611A1 (fr) * 1999-02-18 2000-08-24 Sankyo Company, Limited Preparations de liposomes contenant des medicaments antitumoraux
US20030236325A1 (en) * 2002-05-30 2003-12-25 Michela Bonora Agricultural articles
CA2524478A1 (en) * 2003-05-02 2004-11-18 Aronex Pharmaceuticals, Inc. Lipid platinum complexes and methods of use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS535678B2 (enExample) * 1973-05-30 1978-03-01
US3991045A (en) * 1973-05-30 1976-11-09 Asahi Kasei Kogyo Kabushiki Kaisha N4 -acylarabinonucleosides
DE2614946C2 (de) * 1975-04-08 1987-04-23 Asahi Kasei Kogyo K.K., Osaka Neue Nucleosidderivate
JPS52114015A (en) * 1976-02-24 1977-09-24 Japan Found Cancer Novel cytosine arabinocide preparation

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5888027U (ja) * 1981-12-09 1983-06-15 厚木自動車部品株式会社 カ−ク−ラ用電磁クラツチの制御装置
JPS6416727A (en) * 1987-07-10 1989-01-20 Asahi Chemical Ind Novel medical preparation of ara-c derivative
JPH01113319A (ja) * 1987-10-27 1989-05-02 Nippon Oil & Fats Co Ltd リポソームカプセル化したマクロファージ活性化剤
JPH03115737A (ja) * 1989-09-29 1991-05-16 Mitsubishi Heavy Ind Ltd 可変マツチング機構を有する過給機システム

Also Published As

Publication number Publication date
FR2468365B1 (enExample) 1983-07-01
GB2055578B (en) 1983-10-12
FR2468365A1 (fr) 1981-05-08
JPS5715087B2 (enExample) 1982-03-29
GB2055578A (en) 1981-03-11
US4330534A (en) 1982-05-18

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