JPS56167684A - Novel 6-pyridinyl-4-substituted-3(2h)- pyridazinones, their manufacture and cardiac stimulant thereof - Google Patents
Novel 6-pyridinyl-4-substituted-3(2h)- pyridazinones, their manufacture and cardiac stimulant thereofInfo
- Publication number
- JPS56167684A JPS56167684A JP6510381A JP6510381A JPS56167684A JP S56167684 A JPS56167684 A JP S56167684A JP 6510381 A JP6510381 A JP 6510381A JP 6510381 A JP6510381 A JP 6510381A JP S56167684 A JPS56167684 A JP S56167684A
- Authority
- JP
- Japan
- Prior art keywords
- pyridazinones
- pyridinyl
- substituted
- novel
- manufacture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/55—Acids; Esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/144,563 US4305943A (en) | 1980-04-28 | 1980-04-28 | 4-Amino-6-(pyridinyl)-3(2H)-pyridazinones and their use as cardiotonics |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS56167684A true JPS56167684A (en) | 1981-12-23 |
Family
ID=22509142
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP6510381A Pending JPS56167684A (en) | 1980-04-28 | 1981-04-28 | Novel 6-pyridinyl-4-substituted-3(2h)- pyridazinones, their manufacture and cardiac stimulant thereof |
Country Status (7)
Country | Link |
---|---|
US (1) | US4305943A (ja) |
JP (1) | JPS56167684A (ja) |
KR (1) | KR830005203A (ja) |
BE (1) | BE888566A (ja) |
CA (1) | CA1166253A (ja) |
PH (1) | PH16014A (ja) |
ZA (1) | ZA812652B (ja) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013097052A1 (en) | 2011-12-30 | 2013-07-04 | Abbott Laboratories | Bromodomain inhibitors |
CA3002560A1 (en) | 2015-10-23 | 2017-04-27 | Array Biopharma, Inc. | 2-aryl- and 2-heteroaryl-substituted 2-pyridazin-3(2h)-one compounds as inhibitors of fgfr tyrosine kinases |
EP3693369A3 (en) | 2016-04-15 | 2020-09-09 | AbbVie Inc. | Bromodomain inhibitors |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4072746A (en) * | 1975-10-14 | 1978-02-07 | Sterling Drug Inc. | 3-Amino-5-(pyridinyl)-2(1H)-pyridinones |
US4004012A (en) * | 1975-10-14 | 1977-01-18 | Sterling Drug Inc. | 3-Cyano-5-(pyridinyl)-2(1H)-pyridinones |
-
1980
- 1980-04-28 US US06/144,563 patent/US4305943A/en not_active Expired - Lifetime
-
1981
- 1981-04-22 PH PH25529A patent/PH16014A/en unknown
- 1981-04-23 ZA ZA00812652A patent/ZA812652B/xx unknown
- 1981-04-27 BE BE1/10209A patent/BE888566A/fr not_active IP Right Cessation
- 1981-04-27 KR KR1019810001437A patent/KR830005203A/ko unknown
- 1981-04-27 CA CA000376309A patent/CA1166253A/en not_active Expired
- 1981-04-28 JP JP6510381A patent/JPS56167684A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
BE888566A (fr) | 1981-10-27 |
US4305943A (en) | 1981-12-15 |
KR830005203A (ko) | 1983-08-03 |
PH16014A (en) | 1983-05-20 |
ZA812652B (en) | 1982-05-26 |
CA1166253A (en) | 1984-04-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS57109736A (en) | Manufacture of 1,4-butandiol and tetrahydrofuran | |
JPS56150064A (en) | Novel pyridine compounds, their manufacture and cardiac stimulant thereof | |
DE3268566D1 (en) | 4-(2-fluoro-4-halo-5-substituted phenyl)urazols, and their production and use | |
JPS5716868A (en) | 1-hydroxyethyl-azole derivative,manufacture and use | |
JPS56150090A (en) | Novel imidazopyridine comopounds, their manufacture and cardiac stimulant thereof | |
JPS5756478A (en) | Triazinylaminotriazines, manufacture and use | |
JPS5799565A (en) | Manufacture of 2,3-dichlorosulfonyl- acrylonitrile | |
JPS56161356A (en) | Manufacture of 1-aminopropanediol-2,3 | |
JPS57120536A (en) | Manufacture of 1,2-dichloroethane | |
JPS57136583A (en) | Novel benzimidazole compounds, manufacture and cardiac stimulant | |
JPS5795947A (en) | Manufacture of alpha-hydroxy-carboxyamide, novel intermediate therefor and manufacture | |
JPS56154460A (en) | Manufacture of 2,2,6,6-tetramethylpiperidone-4 | |
JPS56161357A (en) | Manufacture of 1-aminopropanediol-2,3 | |
JPS56139435A (en) | 3,3-dimethyl-1-phenoxy-butan-2-ol and manufacture | |
JPS577469A (en) | Manufacture of 2,3,5-trichloropyridine | |
JPS5748993A (en) | N-phosphonylcarbonyl-carbamates, manufacture and use | |
JPS56167684A (en) | Novel 6-pyridinyl-4-substituted-3(2h)- pyridazinones, their manufacture and cardiac stimulant thereof | |
JPS56161355A (en) | Manufacture of 1-aminopropanediol-2,3 | |
JPS5726636A (en) | 4-substituted 3,3-dimethyl-butane-2-ones and manufacture | |
JPS57140767A (en) | Novel nicotinamide derivative, manufacture and cardiac stimulant | |
JPS5781473A (en) | Manufacture of 1,2,4-triazole | |
JPS5711965A (en) | Aminophenylpyridine cardiac stimulant | |
JPS5732234A (en) | Manufacture of 1,2-dichloroethane | |
JPS57108070A (en) | Pyrazole substituted oxyimino-cyano-acetamide derivative, manufacture and use | |
JPS5777647A (en) | Manufacture of alpha-benzamide-alpha'- halogeno-1,1'-dianthraimide |