JPS56140950A - Production of mandelic acid - Google Patents
Production of mandelic acidInfo
- Publication number
- JPS56140950A JPS56140950A JP4414680A JP4414680A JPS56140950A JP S56140950 A JPS56140950 A JP S56140950A JP 4414680 A JP4414680 A JP 4414680A JP 4414680 A JP4414680 A JP 4414680A JP S56140950 A JPS56140950 A JP S56140950A
- Authority
- JP
- Japan
- Prior art keywords
- mandelic acid
- halogen
- alkali metal
- acid
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: The dehalogenation of a specific alkali metal salt or ammonium salt of halogen-substituted mandelic acid produces a mandelic acid used as an intermediate of medicines from inexpensive raw materials in high yield with industrial avantage.
CONSTITUTION: The dehalogenation of an alkali metal or ammonium salt of halogen-substituted mandelic acid of formula I (X is halogen; R is H, lower alkyl; M is alkali metal, ammonium ion) gives a mandelic acid of formula II. Especially, this process is most suitably applied to the production of 4-hydroxymandelic acid from sodium 3-chloro-4-hydroxymandelate which is readily obtained from glyoxylic acid and o-chlorophenol. The reaction is effected by catalytically dehydrogenating the substrate in an aqueous medium in the presence of a Pd-catalyst such as Pd-C.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4414680A JPS56140950A (en) | 1980-04-03 | 1980-04-03 | Production of mandelic acid |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4414680A JPS56140950A (en) | 1980-04-03 | 1980-04-03 | Production of mandelic acid |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS56140950A true JPS56140950A (en) | 1981-11-04 |
Family
ID=12683488
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP4414680A Pending JPS56140950A (en) | 1980-04-03 | 1980-04-03 | Production of mandelic acid |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56140950A (en) |
-
1980
- 1980-04-03 JP JP4414680A patent/JPS56140950A/en active Pending
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