JPS56127400A - Preparation of saponin by acid hydrolysis - Google Patents
Preparation of saponin by acid hydrolysisInfo
- Publication number
- JPS56127400A JPS56127400A JP6150880A JP6150880A JPS56127400A JP S56127400 A JPS56127400 A JP S56127400A JP 6150880 A JP6150880 A JP 6150880A JP 6150880 A JP6150880 A JP 6150880A JP S56127400 A JPS56127400 A JP S56127400A
- Authority
- JP
- Japan
- Prior art keywords
- saponin
- glucopyranosyl
- substitutent
- saccharide
- eluted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Steroid Compounds (AREA)
Abstract
PURPOSE: To obtain gynosaponin having the same composition as the saponin of Panax ginseng, and useful as a drug, etc., by hydrolyzing a specific novel saponin with a weak acid, thereby eliminating the saccharide from the substitutent at the 20-position while keeping the substitutent at the 3-position unchanged.
CONSTITUTION: A saponin of formula [R1 is [β-D-glucopyranosyl(1→2)-α-L- rhamopyranosyl(1→6)]-β-D-glucopyranosyl group, etc.; R2 is β-D-glucopyranosyl (1→6)-β-D-glucopyranosyl group, etc.] which is a constituent of "Amacha-zuru" (Gynostemapentaphyllum Makino, a plant belonging to Cucurbitaceae family), is hydrolyzed with a weak acid (e.g. acetic acid) to eliminate the saccharide from the substituent group of the 20-position. The hydrolyzed product is if necessary adsorbed with a polystyrene-based adsorbent resin and silica gel, and eluted. The eluate is evaporated to dryness, and developed and eluted by thin layer chromatography using a solvent to obtain the objective compound.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6150880A JPS56127400A (en) | 1980-05-08 | 1980-05-08 | Preparation of saponin by acid hydrolysis |
US06/205,377 US4339442A (en) | 1980-03-11 | 1980-11-07 | Gynosaponins, their use and a process for preparing the same |
DE19803042117 DE3042117A1 (en) | 1980-03-11 | 1980-11-07 | GYNOSAPONINE, METHOD FOR THE PRODUCTION THEREOF AND MEDICAL PREPARATIONS CONTAINING THESE COMPOUNDS |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6150880A JPS56127400A (en) | 1980-05-08 | 1980-05-08 | Preparation of saponin by acid hydrolysis |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP55030636A Division JPS6043359B2 (en) | 1980-03-11 | 1980-03-11 | Gynosaponins and their production method |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56127400A true JPS56127400A (en) | 1981-10-06 |
JPS6352634B2 JPS6352634B2 (en) | 1988-10-19 |
Family
ID=13173098
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP6150880A Granted JPS56127400A (en) | 1980-03-11 | 1980-05-08 | Preparation of saponin by acid hydrolysis |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56127400A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102759597A (en) * | 2011-04-29 | 2012-10-31 | 天津药物研究院 | Rapid detection method of aescin component |
CN112588318A (en) * | 2020-12-15 | 2021-04-02 | 江南大学 | Green and efficient preparation method of short-sugar-chain C21 steroid glycoside of radix cynanchi bungei |
-
1980
- 1980-05-08 JP JP6150880A patent/JPS56127400A/en active Granted
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102759597A (en) * | 2011-04-29 | 2012-10-31 | 天津药物研究院 | Rapid detection method of aescin component |
CN112588318A (en) * | 2020-12-15 | 2021-04-02 | 江南大学 | Green and efficient preparation method of short-sugar-chain C21 steroid glycoside of radix cynanchi bungei |
CN112588318B (en) * | 2020-12-15 | 2022-02-15 | 江南大学 | Green and efficient preparation method of short-sugar-chain C21 steroid glycoside of radix cynanchi bungei |
Also Published As
Publication number | Publication date |
---|---|
JPS6352634B2 (en) | 1988-10-19 |
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