JPS56118018A - Drug composition containing myeloperoxidase as main constituent - Google Patents
Drug composition containing myeloperoxidase as main constituentInfo
- Publication number
- JPS56118018A JPS56118018A JP2211380A JP2211380A JPS56118018A JP S56118018 A JPS56118018 A JP S56118018A JP 2211380 A JP2211380 A JP 2211380A JP 2211380 A JP2211380 A JP 2211380A JP S56118018 A JPS56118018 A JP S56118018A
- Authority
- JP
- Japan
- Prior art keywords
- myeloperoxidase
- drug composition
- halide
- leukocyte
- originating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
PURPOSE: A drug composition, particularly effective atainst resistant tubercle bacillus, and containing myeloperoxidase derived from the leukocyte originating from the human bone marrow and a halide.
CONSTITUTION: A drug composition, effective against bacteria having deficient or reduced catalase synthetic ability, particularly a tubercle bacillus resistant to isonicotinic acid hydrazide, and containing 100W0.05 units myeloperoxidase derived from the leukocyte originating from the human bone marrow and 5W0.05mmol halide, e.g. KI. The myeloperoxidase is an enzyme having a germicidal and antiviral action, capable of producing hypohalite ions in the presence of hydrogen peroxide and halogen ions and believed to exhibit antibacterial action due to the powerful oxidation or halogenating action of the hypohalite. The hydrogen peroxide unusable due to the instability thereof as a medicine can be eliminated by the use of the halide in a specific proportion.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2211380A JPS56118018A (en) | 1980-02-22 | 1980-02-22 | Drug composition containing myeloperoxidase as main constituent |
SE8005679A SE448882B (en) | 1979-12-28 | 1980-08-12 | PROCEDURE FOR THE EXTRACTION OF MYELOPEROXIDAS AND PHARMACEUTICAL COMPOSITION CONTAINING THE ENZYME |
US06/179,783 US4306025A (en) | 1979-12-28 | 1980-08-20 | Method for recovering myeloperoxidase and pharmaceutical composition containing myeloperoxidase as major constituent |
DE3031990A DE3031990C2 (en) | 1979-12-28 | 1980-08-25 | Obtaining myeloperoxidase and medicinal products containing this enzyme as the main component |
FR8018581A FR2472609A1 (en) | 1979-12-28 | 1980-08-27 | PROCESS FOR SEPARATING MYELOPEROXIDASE AND PHARMACEUTICAL COMPOSITION CONTAINING MYELOPEROXIDASE |
AT0436780A AT370997B (en) | 1979-12-28 | 1980-08-28 | METHOD FOR OBTAINING MYELOPEROXIDASE |
IN758/CAL/81A IN153488B (en) | 1979-12-28 | 1981-07-08 | |
US06/297,418 US4379141A (en) | 1979-12-28 | 1981-08-28 | Method for recovering myeloperoxidase and pharmaceutical composition containing myeloperoxidase as major constituent |
GB8233109A GB2108387B (en) | 1979-12-28 | 1982-11-19 | A pharmaceutical composition containing myeloperoxidase |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2211380A JPS56118018A (en) | 1980-02-22 | 1980-02-22 | Drug composition containing myeloperoxidase as main constituent |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS56118018A true JPS56118018A (en) | 1981-09-16 |
Family
ID=12073825
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2211380A Pending JPS56118018A (en) | 1979-12-28 | 1980-02-22 | Drug composition containing myeloperoxidase as main constituent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56118018A (en) |
-
1980
- 1980-02-22 JP JP2211380A patent/JPS56118018A/en active Pending
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