JPS56112907A - Production of polymer composition including bioactive substance - Google Patents

Production of polymer composition including bioactive substance

Info

Publication number
JPS56112907A
JPS56112907A JP1576280A JP1576280A JPS56112907A JP S56112907 A JPS56112907 A JP S56112907A JP 1576280 A JP1576280 A JP 1576280A JP 1576280 A JP1576280 A JP 1576280A JP S56112907 A JPS56112907 A JP S56112907A
Authority
JP
Japan
Prior art keywords
bioactive substance
1w10wt
pieces
ionizing radiation
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1576280A
Other languages
Japanese (ja)
Other versions
JPH0255445B2 (en
Inventor
Fumio Yoshii
Isao Kaetsu
Taku Fujimura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japan Atomic Energy Agency
Original Assignee
Japan Atomic Energy Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Atomic Energy Research Institute filed Critical Japan Atomic Energy Research Institute
Priority to JP1576280A priority Critical patent/JPS56112907A/en
Publication of JPS56112907A publication Critical patent/JPS56112907A/en
Publication of JPH0255445B2 publication Critical patent/JPH0255445B2/ja
Granted legal-status Critical Current

Links

Abstract

PURPOSE: To produce titled composition firmly fixing a bioactive substance at low temperature within a short time, by adding glutaraldehyde to a mixture of a bioactive substance and a vinyl type polymerizable monomer, and irradiating the resulting mixture with an ionizing radiation.
CONSTITUTION: To an aqueous solution or buffer solution containing a bioactive substance such as human adult cornea or cellulase are added 1W10wt% at least one vinyl type polymerizable monomer such as ethylene glycol diacrylate and 1W10wt% glutaraldehyde, and the resulting mixture is irradiated with an ionizing radiation at 0W10°C and at a dosage of about 1×105 Roentgen to polymerize the monomer and to form a fixed product which is the entire system fixed to form a pudding-like material.
EFFECT: It is possible to keep the life for a ling time by cutting the fixed product into pieces of an appropriate size and storing the pieces in a buffer solution.
COPYRIGHT: (C)1981,JPO&Japio
JP1576280A 1980-02-12 1980-02-12 Production of polymer composition including bioactive substance Granted JPS56112907A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP1576280A JPS56112907A (en) 1980-02-12 1980-02-12 Production of polymer composition including bioactive substance

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1576280A JPS56112907A (en) 1980-02-12 1980-02-12 Production of polymer composition including bioactive substance

Publications (2)

Publication Number Publication Date
JPS56112907A true JPS56112907A (en) 1981-09-05
JPH0255445B2 JPH0255445B2 (en) 1990-11-27

Family

ID=11897793

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1576280A Granted JPS56112907A (en) 1980-02-12 1980-02-12 Production of polymer composition including bioactive substance

Country Status (1)

Country Link
JP (1) JPS56112907A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009014468A (en) * 2007-07-04 2009-01-22 Japan Atomic Energy Agency Manufacturing method of biological tissue hardened body

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51124094A (en) * 1975-04-10 1976-10-29 Yeda Res & Dev Method of providing explant
JPS54119585A (en) * 1978-03-09 1979-09-17 Japan Atom Energy Res Inst Production of polymer composition containing physiologically active substance

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51124094A (en) * 1975-04-10 1976-10-29 Yeda Res & Dev Method of providing explant
JPS54119585A (en) * 1978-03-09 1979-09-17 Japan Atom Energy Res Inst Production of polymer composition containing physiologically active substance

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009014468A (en) * 2007-07-04 2009-01-22 Japan Atomic Energy Agency Manufacturing method of biological tissue hardened body

Also Published As

Publication number Publication date
JPH0255445B2 (en) 1990-11-27

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