JPS5583790A - Preparation of 3-substituted thiomethylcephalosporin compound - Google Patents

Preparation of 3-substituted thiomethylcephalosporin compound

Info

Publication number
JPS5583790A
JPS5583790A JP15792478A JP15792478A JPS5583790A JP S5583790 A JPS5583790 A JP S5583790A JP 15792478 A JP15792478 A JP 15792478A JP 15792478 A JP15792478 A JP 15792478A JP S5583790 A JPS5583790 A JP S5583790A
Authority
JP
Japan
Prior art keywords
compound
formula
substituted
thiomethylcephalosporin
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP15792478A
Other languages
Japanese (ja)
Other versions
JPS6340795B2 (en
Inventor
Junichi Nakazawa
Teruo Hashimoto
Masanao Kaneko
Takeo Miyaoka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Priority to JP15792478A priority Critical patent/JPS5583790A/en
Publication of JPS5583790A publication Critical patent/JPS5583790A/en
Publication of JPS6340795B2 publication Critical patent/JPS6340795B2/ja
Granted legal-status Critical Current

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  • Cephalosporin Compounds (AREA)

Abstract

PURPOSE: To obtain the title compound having an antibacterial activity in a short time, by heating an 7-acylamino-3-carbamoyloxymethylcephalosporin compound or its salt with a specific thiol in the presence of a small amount of water.
CONSTITUTION: A compound (C) of formula I (R is H or acyl group; X is H or alkoxy group) or its salt is heated with a thiol of the formula R"SH [R" is (un)substituted heterocyclic group or formula II] in the presence of water in an amount of 5 times or less that of C in the absence of a catalyst to give the compound of formula III.
EFFECT: Simple procedures and high yield.
COPYRIGHT: (C)1980,JPO&Japio
JP15792478A 1978-12-18 1978-12-18 Preparation of 3-substituted thiomethylcephalosporin compound Granted JPS5583790A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP15792478A JPS5583790A (en) 1978-12-18 1978-12-18 Preparation of 3-substituted thiomethylcephalosporin compound

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15792478A JPS5583790A (en) 1978-12-18 1978-12-18 Preparation of 3-substituted thiomethylcephalosporin compound

Publications (2)

Publication Number Publication Date
JPS5583790A true JPS5583790A (en) 1980-06-24
JPS6340795B2 JPS6340795B2 (en) 1988-08-12

Family

ID=15660433

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15792478A Granted JPS5583790A (en) 1978-12-18 1978-12-18 Preparation of 3-substituted thiomethylcephalosporin compound

Country Status (1)

Country Link
JP (1) JPS5583790A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2513195Y2 (en) * 1988-10-31 1996-10-02 株式会社島津製作所 Heat treatment furnace
JPH02197792A (en) * 1989-01-25 1990-08-06 Ishikawajima Harima Heavy Ind Co Ltd Operation of sintering furnace
JPH02309184A (en) * 1989-05-23 1990-12-25 Ishikawajima Harima Heavy Ind Co Ltd Operating method for high pressure sintering furnace

Also Published As

Publication number Publication date
JPS6340795B2 (en) 1988-08-12

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