JPS5551096A - Antitumor protein polyglycoside - Google Patents

Antitumor protein polyglycoside

Info

Publication number
JPS5551096A
JPS5551096A JP12559678A JP12559678A JPS5551096A JP S5551096 A JPS5551096 A JP S5551096A JP 12559678 A JP12559678 A JP 12559678A JP 12559678 A JP12559678 A JP 12559678A JP S5551096 A JPS5551096 A JP S5551096A
Authority
JP
Japan
Prior art keywords
polyglycoside
protein
antitumor
soluble
moiety
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP12559678A
Other languages
Japanese (ja)
Other versions
JPS6116280B2 (en
Inventor
Denichi Mizuno
Masatoshi Yamazaki
Shigeru Abe
Ushio Mikawa
Shoji Shibata
Kunio Takahashi
Nobuo Kanda
Morihiro Kono
Kiyoshi Sato
Nobuyuki Azumabashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Pharmaceutical Co Ltd
Original Assignee
Daiichi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Pharmaceutical Co Ltd filed Critical Daiichi Pharmaceutical Co Ltd
Priority to JP12559678A priority Critical patent/JPS5551096A/en
Publication of JPS5551096A publication Critical patent/JPS5551096A/en
Publication of JPS6116280B2 publication Critical patent/JPS6116280B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

NEW MATERIAL:An antitumor protein polyglycoside DH-6665 comprising D-glucose (G) and D-mannose (M) in the glucide moiety at a ratio of (G) to (M) of 2:1, and glycine, alanine, glutamic acid, and dicyanopimelic acid in the protein moiety, readily soluble in water, soluble in formamide, and slightly soluble in DMSO. Elementary analysis: C, 35-43%; H, 4.8-6.4%; N, 0.5-2.5%, free from halogen and S. Molecular weight: 10,000-300,000. Specific rotatory power: [alpha]D<25>= +30-+70 deg.. USE:Antitumor agents capable of promoting the immunity of hosts. PROCESS:Microellobosporia grisea strains (IFO-12518) are cultured in a liquid medium at 28-37 deg.C, and the objective substance is collected from the filtrate, and purified by gel filtration to give the antitumor protein polyglycoside DH-6665.
JP12559678A 1978-10-12 1978-10-12 Antitumor protein polyglycoside Granted JPS5551096A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12559678A JPS5551096A (en) 1978-10-12 1978-10-12 Antitumor protein polyglycoside

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12559678A JPS5551096A (en) 1978-10-12 1978-10-12 Antitumor protein polyglycoside

Publications (2)

Publication Number Publication Date
JPS5551096A true JPS5551096A (en) 1980-04-14
JPS6116280B2 JPS6116280B2 (en) 1986-04-28

Family

ID=14914054

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12559678A Granted JPS5551096A (en) 1978-10-12 1978-10-12 Antitumor protein polyglycoside

Country Status (1)

Country Link
JP (1) JPS5551096A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63272472A (en) * 1987-04-28 1988-11-09 キユーピー株式会社 Drawing tool for article

Also Published As

Publication number Publication date
JPS6116280B2 (en) 1986-04-28

Similar Documents

Publication Publication Date Title
JPS54140707A (en) Hgi glycoprotein which stimulates proliferation of human granulocyte, preparation of hgi glycoprotein, and remedy for hypoleukocytosis containing hgi glycoprotein
IT8023051A0 (en) SPHERICAL PARTICLES OF ACTIVATED CARBON SUITABLE FOR USE IN PHARMACEUTICAL COMPOSITIONS TO CONTROL POISONING.
JPS5372891A (en) Purifying of microbiological enzyme extract by using synthesized high molecular electrolyte
FR2281340A1 (en) DERIVATIVES OF FOLIC ACID, THEIR PREPARATION PROCESS AND THEIR APPLICATION
FR2306939A1 (en) PROCESS FOR PURIFYING AND INCREASING THE WHITNESS OF NATURAL CALCITE MINERALS
AU568588B2 (en) Flocculating microscopic particles, collecting microalgae and purifying water
GB1502320A (en) Water soluble bacterial extracts containing diaminopimelic acid obtained from corynebacteria
BE877243A (en) PROCESS FOR THE PREPARATION OF O-METHALLYLOXYPHENOL BY SELECTIVE MONOETHERIFICATION OF PYROCATECHINE
JPS5551096A (en) Antitumor protein polyglycoside
BE853302A (en) PROCESS FOR PREPARING ALKYLTHIOMETHYLPHENOLS
BE864121A (en) COMPOSITIONS OF POLYPEPTIDES CONTAINING THE L-ARGININE-L-LYSINE- (L-ASPARTIC ACID) -L-VALINE-L-TYROSINE SEQUENCE, THE PROCESS OF OBTAINING THEM AND THERAPEUTIC COMPOSITIONS CONTAINING
PT69545A (en) NON-POLLUTING OXYHYDROCHLORIZATION PROCESS
EP0462792A3 (en) Process for obtaining cellular protein having anti-hiv activity
BE846141A (en) PROCESS FOR PREPARING 5-OXO-HEXANOIC ACID AND ITS DERIVATIVES
BE865774A (en) PROCESS FOR THE PREPARATION OF 1-AMINO-8-NAPHTOL-3,6-DISULPHONIC ACID (&#34;H&#34; ACID)
JPS5522650A (en) Novel bioactive substance
JPS5646819A (en) Related carcinoembryonic antigen substance
JPS54154792A (en) Novel antibiotic a-11079-b1b and its preparation
FR2308878A1 (en) METHOD AND DEVICE FOR COLLECTING SOLAR ENERGY
PT83787A (en) Improved process for the laboratory diagnosis of infections caused by htlv 222 virus in particular
JPS5387400A (en) Collection of protein
JPS5767593A (en) Novel antibiotic kg-2245 and its preparation
JPS5210492A (en) Preparation of xanthane gum
SU548224A1 (en) Separator for large manure inclusions
Jampani et al. Differential eutrophication of three water bodies in Tenali Town(AP, India) with emphasis on algae as pollution indicator.

Legal Events

Date Code Title Description
A131 Notification of reasons for refusal

Effective date: 20050621

Free format text: JAPANESE INTERMEDIATE CODE: A131

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20050921

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20051107

A521 Written amendment

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20051129

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20060302

A131 Notification of reasons for refusal

Effective date: 20060620

Free format text: JAPANESE INTERMEDIATE CODE: A131

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20060915

A602 Written permission of extension of time

Effective date: 20061106

Free format text: JAPANESE INTERMEDIATE CODE: A602

A521 Written amendment

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20061121

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20070123

A61 First payment of annual fees (during grant procedure)

Effective date: 20070222

Free format text: JAPANESE INTERMEDIATE CODE: A61

R150 Certificate of patent (=grant) or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

LAPS Cancellation because of no payment of annual fees