JPS5517325A - Gelatinous drug for external use, and its preparation - Google Patents

Gelatinous drug for external use, and its preparation

Info

Publication number
JPS5517325A
JPS5517325A JP8978778A JP8978778A JPS5517325A JP S5517325 A JPS5517325 A JP S5517325A JP 8978778 A JP8978778 A JP 8978778A JP 8978778 A JP8978778 A JP 8978778A JP S5517325 A JPS5517325 A JP S5517325A
Authority
JP
Japan
Prior art keywords
solution
preparation
trichophytia
clotrimazole
external use
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP8978778A
Other languages
Japanese (ja)
Other versions
JPS5748090B2 (en
Inventor
Takuzo Joge
Kazuhiko Joge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toko Yakuhin Kogyo KK
Original Assignee
Toko Yakuhin Kogyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toko Yakuhin Kogyo KK filed Critical Toko Yakuhin Kogyo KK
Priority to JP8978778A priority Critical patent/JPS5517325A/en
Priority to US06/056,978 priority patent/US4267169A/en
Priority to DE7979102575T priority patent/DE2965280D1/en
Priority to CA000332237A priority patent/CA1117014A/en
Priority to EP79102575A priority patent/EP0007595B1/en
Priority to ES482723A priority patent/ES482723A1/en
Publication of JPS5517325A publication Critical patent/JPS5517325A/en
Publication of JPS5748090B2 publication Critical patent/JPS5748090B2/ja
Granted legal-status Critical Current

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  • Medicinal Preparation (AREA)

Abstract

PURPOSE: To obtain a gelatinous drug for external use, having pleasant feeling to the skin and high absorbability, by dissolving a fungicide "clotrimazole" in "crotamiton", and adding an alcohol and a polymer to the solution.
CONSTITUTION: Clotrimazole, 1-[(2-chloropheyl)diphenylmethyl]imidazole, which is a fungicide effective to trichophytia pompholyciformus, thnea trichophytia, trichophytia maculovesiculosa, etc., is dissolved in an oleophilic solvent "crotamiton". The solution is added with ethyl alcohol (which may contain ≤ 40% of propylene glycol) and a carboxyvinyl polymer. The solution is neutralized by adding an organic amine while stirring, to obtain the objective clotrimazole-containing preparation having a pH of 4-10 and a viscosity of 2,000-100,000 cps at 20°C. The preparation of this invention is superior to the conventional ethyl alcohol solution or poultice in its durability.
COPYRIGHT: (C)1980,JPO&Japio
JP8978778A 1978-07-22 1978-07-22 Gelatinous drug for external use, and its preparation Granted JPS5517325A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP8978778A JPS5517325A (en) 1978-07-22 1978-07-22 Gelatinous drug for external use, and its preparation
US06/056,978 US4267169A (en) 1978-07-22 1979-07-12 Novel preparation of clotrimazole
DE7979102575T DE2965280D1 (en) 1978-07-22 1979-07-20 Preparations of clotrimazole and process for preparing same
CA000332237A CA1117014A (en) 1978-07-22 1979-07-20 Preparation of clotrimazole
EP79102575A EP0007595B1 (en) 1978-07-22 1979-07-20 Preparations of clotrimazole and process for preparing same
ES482723A ES482723A1 (en) 1978-07-22 1979-07-20 Preparations of clotrimazole and process for preparing same.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8978778A JPS5517325A (en) 1978-07-22 1978-07-22 Gelatinous drug for external use, and its preparation

Publications (2)

Publication Number Publication Date
JPS5517325A true JPS5517325A (en) 1980-02-06
JPS5748090B2 JPS5748090B2 (en) 1982-10-14

Family

ID=13980385

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8978778A Granted JPS5517325A (en) 1978-07-22 1978-07-22 Gelatinous drug for external use, and its preparation

Country Status (1)

Country Link
JP (1) JPS5517325A (en)

Also Published As

Publication number Publication date
JPS5748090B2 (en) 1982-10-14

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