JPS55127372A - 1,3-dioxo-1,2,3,4-tetrahydroisoquinoline derivative and its preparation - Google Patents

1,3-dioxo-1,2,3,4-tetrahydroisoquinoline derivative and its preparation

Info

Publication number
JPS55127372A
JPS55127372A JP3480779A JP3480779A JPS55127372A JP S55127372 A JPS55127372 A JP S55127372A JP 3480779 A JP3480779 A JP 3480779A JP 3480779 A JP3480779 A JP 3480779A JP S55127372 A JPS55127372 A JP S55127372A
Authority
JP
Japan
Prior art keywords
halogen
dioxo
alkyl
compound
tetrahydroisoquinoline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP3480779A
Other languages
Japanese (ja)
Inventor
Kazuo Kubo
Tokuki Ito
Yasuo Isomura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Priority to JP3480779A priority Critical patent/JPS55127372A/en
Publication of JPS55127372A publication Critical patent/JPS55127372A/en
Pending legal-status Critical Current

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  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A 1,3-dioxo-1,2,3,4-tetrahydroisoquinoline derivative of formula I [R1 is halogen or alkyl; R2 is H, halogen, nitro, alkyl, alkoxy, or II (R3,4 are H, alkyl, etc.); X is H, halogen, or II; Y is halogen, OH, alkoxy, or II; n is 2 or 3].
EXAMPLE: 3-( 4-Chloro-4-methyl-1,3-dioxo-1,2,3,4-tetrahydroisoquinoline-2-yl )propanesulfonyl chloride.
USE: Medicine having analgesic, antiphlogistic, muscle relaxing, blood platelet coagulation inhibiting, bacteriostatic, and CNS-suppressing effects, or its intermediate.
PROCESS: For example, a compound III (R1' is H or alkyl; m is 0 or 2) is converted to a compound IV (X' is halogen; Y' is halogen, etc.) by the oxidative halogenation. The compound IV is, if necessary, reduced, aminated and/or hydrolyzed.
COPYRIGHT: (C)1980,JPO&Japio
JP3480779A 1979-03-24 1979-03-24 1,3-dioxo-1,2,3,4-tetrahydroisoquinoline derivative and its preparation Pending JPS55127372A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP3480779A JPS55127372A (en) 1979-03-24 1979-03-24 1,3-dioxo-1,2,3,4-tetrahydroisoquinoline derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3480779A JPS55127372A (en) 1979-03-24 1979-03-24 1,3-dioxo-1,2,3,4-tetrahydroisoquinoline derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS55127372A true JPS55127372A (en) 1980-10-02

Family

ID=12424482

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3480779A Pending JPS55127372A (en) 1979-03-24 1979-03-24 1,3-dioxo-1,2,3,4-tetrahydroisoquinoline derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS55127372A (en)

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