JPS55127372A - 1,3-dioxo-1,2,3,4-tetrahydroisoquinoline derivative and its preparation - Google Patents
1,3-dioxo-1,2,3,4-tetrahydroisoquinoline derivative and its preparationInfo
- Publication number
- JPS55127372A JPS55127372A JP3480779A JP3480779A JPS55127372A JP S55127372 A JPS55127372 A JP S55127372A JP 3480779 A JP3480779 A JP 3480779A JP 3480779 A JP3480779 A JP 3480779A JP S55127372 A JPS55127372 A JP S55127372A
- Authority
- JP
- Japan
- Prior art keywords
- halogen
- dioxo
- alkyl
- compound
- tetrahydroisoquinoline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A 1,3-dioxo-1,2,3,4-tetrahydroisoquinoline derivative of formula I [R1 is halogen or alkyl; R2 is H, halogen, nitro, alkyl, alkoxy, or II (R3,4 are H, alkyl, etc.); X is H, halogen, or II; Y is halogen, OH, alkoxy, or II; n is 2 or 3].
EXAMPLE: 3-( 4-Chloro-4-methyl-1,3-dioxo-1,2,3,4-tetrahydroisoquinoline-2-yl )propanesulfonyl chloride.
USE: Medicine having analgesic, antiphlogistic, muscle relaxing, blood platelet coagulation inhibiting, bacteriostatic, and CNS-suppressing effects, or its intermediate.
PROCESS: For example, a compound III (R1' is H or alkyl; m is 0 or 2) is converted to a compound IV (X' is halogen; Y' is halogen, etc.) by the oxidative halogenation. The compound IV is, if necessary, reduced, aminated and/or hydrolyzed.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3480779A JPS55127372A (en) | 1979-03-24 | 1979-03-24 | 1,3-dioxo-1,2,3,4-tetrahydroisoquinoline derivative and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3480779A JPS55127372A (en) | 1979-03-24 | 1979-03-24 | 1,3-dioxo-1,2,3,4-tetrahydroisoquinoline derivative and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS55127372A true JPS55127372A (en) | 1980-10-02 |
Family
ID=12424482
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP3480779A Pending JPS55127372A (en) | 1979-03-24 | 1979-03-24 | 1,3-dioxo-1,2,3,4-tetrahydroisoquinoline derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55127372A (en) |
-
1979
- 1979-03-24 JP JP3480779A patent/JPS55127372A/en active Pending
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