JPS5511586A - 1-n-(omega-amino-alpha-hydroxyalkanoyl) derivative of 4'-deoxy-6'-n- methylkanamycin a - Google Patents

1-n-(omega-amino-alpha-hydroxyalkanoyl) derivative of 4'-deoxy-6'-n- methylkanamycin a

Info

Publication number
JPS5511586A
JPS5511586A JP8390479A JP8390479A JPS5511586A JP S5511586 A JPS5511586 A JP S5511586A JP 8390479 A JP8390479 A JP 8390479A JP 8390479 A JP8390479 A JP 8390479A JP S5511586 A JPS5511586 A JP S5511586A
Authority
JP
Japan
Prior art keywords
derivative
formula
effected
methylkanamycin
hydroxyalkanoyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP8390479A
Other languages
English (en)
Japanese (ja)
Other versions
JPS636556B2 (en, 2012
Inventor
Takayuki Naito
Susumu Nakagawa
Soichiro Toda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BRISTOL MAYERS KENKYUSHO KK
Bristol Banyu Research Institute Ltd
Original Assignee
BRISTOL MAYERS KENKYUSHO KK
Bristol Banyu Research Institute Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BRISTOL MAYERS KENKYUSHO KK, Bristol Banyu Research Institute Ltd filed Critical BRISTOL MAYERS KENKYUSHO KK
Publication of JPS5511586A publication Critical patent/JPS5511586A/ja
Publication of JPS636556B2 publication Critical patent/JPS636556B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
JP8390479A 1978-07-10 1979-07-04 1-n-(omega-amino-alpha-hydroxyalkanoyl) derivative of 4'-deoxy-6'-n- methylkanamycin a Granted JPS5511586A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/923,283 US4181797A (en) 1978-07-10 1978-07-10 1-N-(ω-amino-α-hydroxyalkanoyl) derivatives of 4'-deoxy-6'-N-methylkanamycin A

Publications (2)

Publication Number Publication Date
JPS5511586A true JPS5511586A (en) 1980-01-26
JPS636556B2 JPS636556B2 (en, 2012) 1988-02-10

Family

ID=25448440

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8390479A Granted JPS5511586A (en) 1978-07-10 1979-07-04 1-n-(omega-amino-alpha-hydroxyalkanoyl) derivative of 4'-deoxy-6'-n- methylkanamycin a

Country Status (2)

Country Link
US (1) US4181797A (en, 2012)
JP (1) JPS5511586A (en, 2012)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60102350A (ja) * 1983-11-09 1985-06-06 Fuji Xerox Co Ltd 複写機
JPH0252854U (en, 2012) * 1988-10-04 1990-04-17

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7794713B2 (en) 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
US20080213274A1 (en) * 2005-10-28 2008-09-04 Sabbadini Roger A Compositions and methods for the treatment and prevention of fibrotic, inflammatory, and neovascularization conditions of the eye
US20090074720A1 (en) * 2005-10-28 2009-03-19 Sabbadini Roger A Methods for decreasing immune response and treating immune conditions
US7862812B2 (en) * 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3781268A (en) * 1972-01-27 1973-12-25 Bristol Myers Co Antibiotic derivatives of kanamycin
JPS5220991B2 (en, 2012) * 1972-08-23 1977-06-07
US3886139A (en) * 1973-02-23 1975-05-27 Bristol Myers Co Derivatives of kanamycin
US3904597A (en) * 1973-02-23 1975-09-09 Bristol Myers Co Antibiotic derivatives
US3886138A (en) * 1973-12-21 1975-05-27 Bristol Myers Co 4{40 -Deoxykanamycin A

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60102350A (ja) * 1983-11-09 1985-06-06 Fuji Xerox Co Ltd 複写機
JPH0252854U (en, 2012) * 1988-10-04 1990-04-17

Also Published As

Publication number Publication date
JPS636556B2 (en, 2012) 1988-02-10
US4181797A (en) 1980-01-01

Similar Documents

Publication Publication Date Title
Kobayashi et al. New phenylethanoid glycosides from Cistanche tubulosa (SCHRENK) HOOK. f. I.
US3923784A (en) Erythromycin a derivatives
US4056616A (en) Rosamicin derivatives and method of using same
JPS5615299A (en) Rhodomycin group antibiotic and its preparation
US4245045A (en) Method of producing anthracycline antibiotics
JPS5511586A (en) 1-n-(omega-amino-alpha-hydroxyalkanoyl) derivative of 4'-deoxy-6'-n- methylkanamycin a
Adegawa et al. Sesquiterpene lactones from Diaspananthus uniflorus (SCH. BIP.) KITAM
US4017607A (en) 9,3",4"-Triacyl ester of the antibiotic SF-837 M1 substance and the production thereof
US4209588A (en) Process for producing new antitumor anthracycline antibiotics
ITO et al. A new antiviral antibiotic SF-2140 produced by Actinomadura
US4291021A (en) Novel macrolide antibiotics and preparation thereof
Ahmad et al. Alkaloidal constituents of Fumaria indica
JPS5756494A (en) New anthracyclin derivative
US3792035A (en) Mono-acetyl derivatives of antibiotic sf-837 and sf-837-a2 substances and production thereof
JPS5515445A (en) Introduction of amino-protecting group by microorganism
US4282152A (en) Intermediates for preparing spectinomycin and analogs thereof
Tanahashi et al. Secoiridoid glucosides from Jasminum mesnyi
Umezawa et al. Synthesis of dihydrostreptobiosamine
US3372090A (en) Streptonigrin antibiotics and process for their production
Umezawa et al. The Partial Structureof Kanamycin
US3423398A (en) Sangivamycin and derivatives thereof
Miyase et al. Ionone and Bibenzyl Glycosides from Epimedium grandiflorum var. thunbergianum
Kawaguchi et al. Studies on Coumermycin, a New Antibiotic III. Structure of Coumermycin A2
Popov et al. A new iridoid precursor of gentiopicroside
KONDA et al. Structure of antitumor alkaloid AM-6201