JPS55105615A - Microcapsule comprising hydrophobic medical substance and its preparation - Google Patents
Microcapsule comprising hydrophobic medical substance and its preparationInfo
- Publication number
- JPS55105615A JPS55105615A JP1486279A JP1486279A JPS55105615A JP S55105615 A JPS55105615 A JP S55105615A JP 1486279 A JP1486279 A JP 1486279A JP 1486279 A JP1486279 A JP 1486279A JP S55105615 A JPS55105615 A JP S55105615A
- Authority
- JP
- Japan
- Prior art keywords
- high polymer
- water
- medical substance
- hydrophobic medical
- substance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicinal Preparation (AREA)
Abstract
PURPOSE: To obtain the title capsules stable for a long time, having double capsule films, mde from gelatin, an enteric high polymer electrolyte soluble in water of specific pH, and a specific high polymer as constituents, containing a hydrophobic medical substance.
CONSTITUTION: (A) A high polymer, e.g. polystyrene, which is soluble in organic solvents immiscible with water, but insoluble in those miscible with water, is dissolved in an organic solvent immiscible with water, and (B) a hydrophobic medical substance is incorporated into the solution. The core substances are then dissolved in (C) an enteric high polymer electrolyte, e.g. methyl acrylate, and subjected to complex coacervation with an adjusted pH, cooled and gelatinized to give microcapsules comprising double films, wherein (a) a wall film consists of the said high polymer (A) surrounding particles of the substance (B), and (b) a complex coacervated wall film consists of the gelatin and electrolyte (C) surrounding the film (a).
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1486279A JPS5910642B2 (en) | 1979-02-09 | 1979-02-09 | Microcapsules containing hydrophobic pharmaceutical substances and their production method |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1486279A JPS5910642B2 (en) | 1979-02-09 | 1979-02-09 | Microcapsules containing hydrophobic pharmaceutical substances and their production method |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS55105615A true JPS55105615A (en) | 1980-08-13 |
JPS5910642B2 JPS5910642B2 (en) | 1984-03-10 |
Family
ID=11872825
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1486279A Expired JPS5910642B2 (en) | 1979-02-09 | 1979-02-09 | Microcapsules containing hydrophobic pharmaceutical substances and their production method |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5910642B2 (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1736134A1 (en) * | 2005-06-22 | 2006-12-27 | L'Oréal | Spherical optical structure |
WO2008006762A2 (en) * | 2006-07-13 | 2008-01-17 | Basf Se | Polyelectrolyte-modified microcapsules |
JP2015034253A (en) * | 2013-08-09 | 2015-02-19 | 花王株式会社 | Method for treating hard surface |
JP2015518031A (en) * | 2012-06-01 | 2015-06-25 | ガルデルマ・リサーチ・アンド・デヴェロップメント | Retinoid-containing microcapsule, method for preparing the same, and pharmaceutical composition containing the retinoid-containing microcapsule |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62115338U (en) * | 1986-01-11 | 1987-07-22 |
-
1979
- 1979-02-09 JP JP1486279A patent/JPS5910642B2/en not_active Expired
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1736134A1 (en) * | 2005-06-22 | 2006-12-27 | L'Oréal | Spherical optical structure |
WO2008006762A2 (en) * | 2006-07-13 | 2008-01-17 | Basf Se | Polyelectrolyte-modified microcapsules |
WO2008006762A3 (en) * | 2006-07-13 | 2008-03-06 | Basf Ag | Polyelectrolyte-modified microcapsules |
US8460791B2 (en) | 2006-07-13 | 2013-06-11 | Basf Aktiengesellschaft | Polyelectrolyte-modified microcapsules |
JP2015518031A (en) * | 2012-06-01 | 2015-06-25 | ガルデルマ・リサーチ・アンド・デヴェロップメント | Retinoid-containing microcapsule, method for preparing the same, and pharmaceutical composition containing the retinoid-containing microcapsule |
JP2015034253A (en) * | 2013-08-09 | 2015-02-19 | 花王株式会社 | Method for treating hard surface |
Also Published As
Publication number | Publication date |
---|---|
JPS5910642B2 (en) | 1984-03-10 |
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