JPS55105615A - Microcapsule comprising hydrophobic medical substance and its preparation - Google Patents

Microcapsule comprising hydrophobic medical substance and its preparation

Info

Publication number
JPS55105615A
JPS55105615A JP1486279A JP1486279A JPS55105615A JP S55105615 A JPS55105615 A JP S55105615A JP 1486279 A JP1486279 A JP 1486279A JP 1486279 A JP1486279 A JP 1486279A JP S55105615 A JPS55105615 A JP S55105615A
Authority
JP
Japan
Prior art keywords
high polymer
water
medical substance
hydrophobic medical
substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1486279A
Other languages
Japanese (ja)
Other versions
JPS5910642B2 (en
Inventor
Masayoshi Samejima
Goichi Hirata
Yoshinori Kobayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Priority to JP1486279A priority Critical patent/JPS5910642B2/en
Publication of JPS55105615A publication Critical patent/JPS55105615A/en
Publication of JPS5910642B2 publication Critical patent/JPS5910642B2/en
Expired legal-status Critical Current

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  • Medicinal Preparation (AREA)

Abstract

PURPOSE: To obtain the title capsules stable for a long time, having double capsule films, mde from gelatin, an enteric high polymer electrolyte soluble in water of specific pH, and a specific high polymer as constituents, containing a hydrophobic medical substance.
CONSTITUTION: (A) A high polymer, e.g. polystyrene, which is soluble in organic solvents immiscible with water, but insoluble in those miscible with water, is dissolved in an organic solvent immiscible with water, and (B) a hydrophobic medical substance is incorporated into the solution. The core substances are then dissolved in (C) an enteric high polymer electrolyte, e.g. methyl acrylate, and subjected to complex coacervation with an adjusted pH, cooled and gelatinized to give microcapsules comprising double films, wherein (a) a wall film consists of the said high polymer (A) surrounding particles of the substance (B), and (b) a complex coacervated wall film consists of the gelatin and electrolyte (C) surrounding the film (a).
COPYRIGHT: (C)1980,JPO&Japio
JP1486279A 1979-02-09 1979-02-09 Microcapsules containing hydrophobic pharmaceutical substances and their production method Expired JPS5910642B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP1486279A JPS5910642B2 (en) 1979-02-09 1979-02-09 Microcapsules containing hydrophobic pharmaceutical substances and their production method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1486279A JPS5910642B2 (en) 1979-02-09 1979-02-09 Microcapsules containing hydrophobic pharmaceutical substances and their production method

Publications (2)

Publication Number Publication Date
JPS55105615A true JPS55105615A (en) 1980-08-13
JPS5910642B2 JPS5910642B2 (en) 1984-03-10

Family

ID=11872825

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1486279A Expired JPS5910642B2 (en) 1979-02-09 1979-02-09 Microcapsules containing hydrophobic pharmaceutical substances and their production method

Country Status (1)

Country Link
JP (1) JPS5910642B2 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1736134A1 (en) * 2005-06-22 2006-12-27 L'Oréal Spherical optical structure
WO2008006762A2 (en) * 2006-07-13 2008-01-17 Basf Se Polyelectrolyte-modified microcapsules
JP2015034253A (en) * 2013-08-09 2015-02-19 花王株式会社 Method for treating hard surface
JP2015518031A (en) * 2012-06-01 2015-06-25 ガルデルマ・リサーチ・アンド・デヴェロップメント Retinoid-containing microcapsule, method for preparing the same, and pharmaceutical composition containing the retinoid-containing microcapsule

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62115338U (en) * 1986-01-11 1987-07-22

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1736134A1 (en) * 2005-06-22 2006-12-27 L'Oréal Spherical optical structure
WO2008006762A2 (en) * 2006-07-13 2008-01-17 Basf Se Polyelectrolyte-modified microcapsules
WO2008006762A3 (en) * 2006-07-13 2008-03-06 Basf Ag Polyelectrolyte-modified microcapsules
US8460791B2 (en) 2006-07-13 2013-06-11 Basf Aktiengesellschaft Polyelectrolyte-modified microcapsules
JP2015518031A (en) * 2012-06-01 2015-06-25 ガルデルマ・リサーチ・アンド・デヴェロップメント Retinoid-containing microcapsule, method for preparing the same, and pharmaceutical composition containing the retinoid-containing microcapsule
JP2015034253A (en) * 2013-08-09 2015-02-19 花王株式会社 Method for treating hard surface

Also Published As

Publication number Publication date
JPS5910642B2 (en) 1984-03-10

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