JPS5498752A - Spiro compound and its preparation - Google Patents
Spiro compound and its preparationInfo
- Publication number
- JPS5498752A JPS5498752A JP15917777A JP15917777A JPS5498752A JP S5498752 A JPS5498752 A JP S5498752A JP 15917777 A JP15917777 A JP 15917777A JP 15917777 A JP15917777 A JP 15917777A JP S5498752 A JPS5498752 A JP S5498752A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- preparation
- decarboxylation
- spiro compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:Compounds of formula (ring A may be substituted with lower alkyls, nitro or halogens).
EXAMPLE: Spiro[benzo[b]furane-2(3H),1'-cyclopropane]-3-one.
USE: Antiulcer agent, anti-inflammatory or analgesic.
PREPARATION: The decarboxylation of a compound of formula II is effected in an adequate solvent in the presence of a catalyst promoting the decarboxylation as metal halide or quarternary ammonium salt under an inert gas atmosphere at 100W 200, preferably 140W160°C to produce the objective compound of formula I. The compound of formula II is prepared through processes shown in reaction equations.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15917777A JPS5498752A (en) | 1977-12-27 | 1977-12-27 | Spiro compound and its preparation |
DK574078A DK149891C (en) | 1977-12-27 | 1978-12-21 | METHOD OF ANALOGUE FOR THE PREPARATION OF SPIROBENZOFURANON COMPOUNDS OR SALTS THEREOF WITH INORGANIC OR ORGANIC ACIDS OR ALKALIMETALS |
HU78TA1504A HU179601B (en) | 1977-12-27 | 1978-12-21 | Process for producing spirobenzofuranone derivatives |
CA318,527A CA1113467A (en) | 1977-12-27 | 1978-12-22 | Spirobenzofuranone compounds |
NO78784367A NO151155C (en) | 1977-12-27 | 1978-12-22 | ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY EFFECTIVE SPIROBENZOFURANON COMPOUNDS |
AU42870/78A AU521851B2 (en) | 1977-12-07 | 1978-12-22 | Spirodenzofuranone compounds |
SU782700556A SU1044225A3 (en) | 1977-12-27 | 1978-12-26 | Process for preparing spirobenzofuran compounds |
ES476330A ES476330A1 (en) | 1977-12-27 | 1978-12-26 | Spirobenzofuranone compounds, processes for their preparation and their use as medicines. |
ZA00787296A ZA787296B (en) | 1977-12-27 | 1978-12-27 | Spirobenzofuranone compounds |
EP78300912A EP0003084B1 (en) | 1977-12-27 | 1978-12-27 | Spirobenzofuranone compounds, processes for their preparation and their use as medicines |
DE7878300912T DE2861651D1 (en) | 1977-12-27 | 1978-12-27 | Spirobenzofuranone compounds, processes for their preparation and their use as medicines |
AT0928478A AT372954B (en) | 1977-12-27 | 1978-12-27 | METHOD FOR PRODUCING NEW SPIROBENZOFURANONE COMPOUNDS |
ES488332A ES8102114A1 (en) | 1977-12-27 | 1980-02-07 | Spirobenzofuranone compounds, processes for their preparation and their use as medicines. |
US06/257,316 US4342779A (en) | 1977-12-27 | 1981-04-17 | 7-Acetylspirobenzofuranone compound |
SG838/84A SG83884G (en) | 1977-12-27 | 1984-11-23 | Spirobenzofuranone compounds,processes for their preparation and their use as medicines |
HK62/85A HK6285A (en) | 1977-12-27 | 1985-01-24 | Spirobenzofuranone compounds,processes for their preparation and their use as medicines |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15917777A JPS5498752A (en) | 1977-12-27 | 1977-12-27 | Spiro compound and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5498752A true JPS5498752A (en) | 1979-08-03 |
Family
ID=15687972
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP15917777A Pending JPS5498752A (en) | 1977-12-07 | 1977-12-27 | Spiro compound and its preparation |
Country Status (2)
Country | Link |
---|---|
JP (1) | JPS5498752A (en) |
ZA (1) | ZA787296B (en) |
-
1977
- 1977-12-27 JP JP15917777A patent/JPS5498752A/en active Pending
-
1978
- 1978-12-27 ZA ZA00787296A patent/ZA787296B/en unknown
Also Published As
Publication number | Publication date |
---|---|
ZA787296B (en) | 1979-12-27 |
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