JPS5492971A - Substitution and dequaternary method of pyridylethyl quaternary salt by pyridine and pyridine base - Google Patents

Substitution and dequaternary method of pyridylethyl quaternary salt by pyridine and pyridine base

Info

Publication number
JPS5492971A
JPS5492971A JP15357778A JP15357778A JPS5492971A JP S5492971 A JPS5492971 A JP S5492971A JP 15357778 A JP15357778 A JP 15357778A JP 15357778 A JP15357778 A JP 15357778A JP S5492971 A JPS5492971 A JP S5492971A
Authority
JP
Japan
Prior art keywords
pyridine
dequaternary
substitution
quaternary salt
base
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP15357778A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6130662B2 (enExample
Inventor
Dei Bairii Toomasu
Kei Matsukugiru Chiyaaruzu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Reilly Tar and Chemical Corp
Original Assignee
Reilly Tar and Chemical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reilly Tar and Chemical Corp filed Critical Reilly Tar and Chemical Corp
Publication of JPS5492971A publication Critical patent/JPS5492971A/ja
Publication of JPS6130662B2 publication Critical patent/JPS6130662B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/22—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing two or more pyridine rings directly linked together, e.g. bipyridyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/68—One oxygen atom attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP15357778A 1977-12-15 1978-12-12 Substitution and dequaternary method of pyridylethyl quaternary salt by pyridine and pyridine base Granted JPS5492971A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/860,787 US4158093A (en) 1977-12-15 1977-12-15 Process for substituting and dequaternizing pyridylethyl quaternary salts of pyridine and bypyridine bases

Publications (2)

Publication Number Publication Date
JPS5492971A true JPS5492971A (en) 1979-07-23
JPS6130662B2 JPS6130662B2 (enExample) 1986-07-15

Family

ID=25334010

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15357778A Granted JPS5492971A (en) 1977-12-15 1978-12-12 Substitution and dequaternary method of pyridylethyl quaternary salt by pyridine and pyridine base

Country Status (4)

Country Link
US (1) US4158093A (enExample)
EP (1) EP0002901B1 (enExample)
JP (1) JPS5492971A (enExample)
DE (1) DE2861828D1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202018101345U1 (de) 2018-03-09 2018-04-06 Lee Fook Yuen Bürste mit umspritzten Bürstenstreifen

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4513141A (en) * 1983-04-28 1985-04-23 General Electric Company Method for making aromatic ethers using diorganoamino pyridinum salt catalyst
US4772713A (en) * 1985-01-16 1988-09-20 Nepera, Inc. Quaternary pyridine salts useful for preparation of 4-substituted pyridines
US4672121A (en) * 1985-01-16 1987-06-09 Nepera Chemical Co. Preparation of 4-substituted pyridines using quaternary pyridine salts
GB8531625D0 (en) * 1985-12-23 1986-02-05 Shell Int Research Complex-forming polymers
DE19637043A1 (de) * 1996-09-12 1998-03-19 Boehringer Mannheim Gmbh Neue Aminoalkoholderivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel und Reagenzien
US7097854B2 (en) 1996-09-12 2006-08-29 Medigene Oncology Gmbh Amino alcohol derivatives, process for their production and pharmaceutical preparations and reagents containing these compounds
AU8681498A (en) * 1997-08-01 1999-02-22 Reilly Industries, Inc. Supernucleophilic 4-substituted-pyridine catalysts, and processes useful for preparing same
WO2000043363A1 (en) * 1999-01-21 2000-07-27 Reilly Industries, Inc. Low-dusting, flowable aminopyridine products
ATE309219T1 (de) * 2002-11-28 2005-11-15 Jubilant Organosys Ltd Verfahren zur herstellung von 4- dimethylaminopyridin (4-dmap)
CN102993144B (zh) * 2012-12-07 2016-04-13 青岛前线生物工程有限公司 4-氨基四氢吡喃的一锅法合成工艺
WO2017127654A1 (en) * 2016-01-21 2017-07-27 Archer Daniels Midland Company Methods for catalyst separation and recovery
CN111320572B (zh) * 2020-04-15 2021-07-23 杭州瑞思新材料有限公司 一种取代吡啶的制备方法
CN118638049A (zh) * 2024-08-15 2024-09-13 湖南斯派克科技股份有限公司 一种4-二甲氨基吡啶的制备工艺

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2742463A (en) * 1956-04-17 Dichlqrostyrylpyridinium compound
US2512789A (en) * 1946-10-24 1950-06-27 Francis E Cislak Pyridinium compounds
US3049547A (en) * 1961-05-31 1962-08-14 Reilly Tar & Chem Corp Dipyridyl quaternary salts
GB1244179A (en) * 1968-03-15 1971-08-25 Ici Ltd Synthesis of n,n'-disubstituted bipyridylium salts
GB1399099A (en) * 1971-11-15 1975-06-25 Ici Ltd Manufacture of bipyridyls

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202018101345U1 (de) 2018-03-09 2018-04-06 Lee Fook Yuen Bürste mit umspritzten Bürstenstreifen

Also Published As

Publication number Publication date
JPS6130662B2 (enExample) 1986-07-15
EP0002901A1 (en) 1979-07-11
US4158093A (en) 1979-06-12
DE2861828D1 (en) 1982-07-01
EP0002901B1 (en) 1982-05-12

Similar Documents

Publication Publication Date Title
JPS5218309A (en) Method of producing halogenated silver emulsion
DE2861828D1 (en) Process for substituting and dequaternizing pyridyl-ethyl quaternary salts of pyridine and bipyridine bases
GB1538670A (en) Method of preparing styrene
JPS52102282A (en) 11nitroo99alkylaminoalkylamino acridine and its salt and method of their preparation
JPS5398972A (en) Method of producing pyridones
JPS53116099A (en) Method of perforation
PT68907A (en) Method of preparing new quaternary ammonium salts of certain phenylpropylamines and phenylbutylamines
JPS537668A (en) Improved method of preparation of sulfinyl chloride
JPS5392782A (en) Method of producing pyridine and 33methylpyridine
GR60787B (en) Preparation process of n2-arylsulfonyl-l-argininamides and salts thereof
JPS53132576A (en) Method of producing pyridoxine
CS194843B2 (en) Method of preparing auranofine
JPS5392781A (en) Method of producing 22methlpyridine and 33 methylpyridine
JPS5211927A (en) Method of producing halogenated silver emulsion
JPS5419915A (en) Method of making organo polarity solution of acrylamidalkanesulfonate metal salt
SU755203A3 (en) Method of preparing 4-androsten-3-ones or their potassium salts
JPS5415984A (en) Method of forming airrinntire
JPS5399316A (en) Stbilyzing method of leserpine preparation
JPS5412363A (en) Heat stabilizing method of sterol
JPS5432478A (en) Preparation of substituted pyridine
IL52883A (en) Preparation of substituted pyridines
JPS5251372A (en) New 11sulphonyll44aminoo pyridinium salt and preparation method thereof
JPS5251376A (en) Benzylpyrimidines and salt and preparation method thereof
JPS5441892A (en) Quaternary salt derivative
JPS52105155A (en) Diphenylarylaminoalkanol quarternary salt derivatives and process for preparing same